http://www.cnr.it/ontology/cnr/individuo/prodotto/ID102283
Seasonal Variation of DNA Integrity Assessed by Comet Assay in Buffalo (Bubalus bubalis) (Abstract/Poster in rivista)
- Type
- Label
- Seasonal Variation of DNA Integrity Assessed by Comet Assay in Buffalo (Bubalus bubalis) (Abstract/Poster in rivista) (literal)
- Anno
- 2006-01-01T00:00:00+01:00 (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#doi
- 10.1111/j.1439-0531.2006.00728.x (literal)
- Alternative label
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori
- Gliozzi T.M., Stacchezzini M.C., Arrighi S. and Cremonesi F. (literal)
- Pagina inizio
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#altreInformazioni
- Poster presentato a: 10th annual conference of the European Society for Domestic Animal Reproduction, 7th - 9th September 2006, Portoroz-Lipica, Slovenia. Abstract pubblicato sulla rivista Reproduction in domestic animals, 2006, 41: 211. (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume
- Rivista
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#note
- Abstract: Reproduction in Domestic Animals, 2006;41:311,P3. (literal)
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#descrizioneSinteticaDelProdotto
- Variazione stagionale dellintegrità del DNA in spermatozoi di bufalo valutata mediante Comet Assay. (literal)
- Note
- Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni
- GTM: IBBA, CNR; SMC, CF: Dipartimento di Scienze Cliniche Veterinarie, UNIMI; AS: Dipartimento di Scienze e Tecnologie Veterinarie per la Sicurezza Alimentare, UNIMI (literal)
- Titolo
- Seasonal Variation of DNA Integrity Assessed by Comet Assay in Buffalo (Bubalus bubalis) (literal)
- Abstract
- In buffalo, seasonal differences of sperm fertility might be related to
the occurrence of DNA damage. The occurrence of DNA strand
breakage damage was evaluated all year round using the comet assay.
Semen of buffaloes A and B was collected each month from December
to November. Ejaculates were assessed using a computer sperm
analyzer. Spermatozoa (106/ml) embedded in low melting point
agarose on a microscope slide were lysed, DNA was unwound and
electrophoresis carried out (pH 11). Four replicates were performed
for each sample. DNA was visualised after staining with ethidium
bromide, 200 sperm cells per slide were scored for the presence and
absence of comets (DNA-damaged cells). The percentage differences
among months and subjects were assessed by ANOVA. Comet percentages
were higher in June (A = 40 ± 2%; B = 20 ± 4%) and July
(A = 9 ± 1%; B = 44 ± 2%) than in April (A = 5 ± 1%;
B = 8 ± 1%) and September (A = 2 ± 1%; B = 1 ± 2%).
Observed values were significantly different (p < 0.01) in June (buffalo
A) and July (buffalo B) compared with the overall trend. Our data
suggest an increase of DNA damage in the summer period (despite an
observed increase in blood testosterone values), with a slight time shift
between subjects. It is concluded that seasonality may exert a
biological effect on the regulation of the apoptotic process at the
testicular level, which has negative consequences on sperm fertility.
This preliminary study addresses concerns that seasonal variations
observed in buffalo reproductive function are related to spermatozoa
integrity (Supported by MIUR COFIN). (literal)
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- Autore CNR
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