Immunocytochemical study by two photons fluorescence microscopi of the distribution of GABAA receptor subunits in rat cerebellar granule cells in culture. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• Immunocytochemical study by two photons fluorescence microscopi of the distribution of GABAA receptor subunits in rat cerebellar granule cells in culture. (Articolo in rivista) (literal)

Anno

• 2004-01-01T00:00:00+01:00 (literal)

Alternative label

• Merlo F. 1, Balduzzi R. 1, Cupello A. 2, Robello M. 1 (2004)
  Immunocytochemical study by two photons fluorescence microscopi of the distribution of GABAA receptor subunits in rat cerebellar granule cells in culture.
  in Amino acids (Wien, Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Merlo F. 1, Balduzzi R. 1, Cupello A. 2, Robello M. 1 (literal)

Pagina inizio

• 77 (literal)

Pagina fine

• 84 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 26 (literal)

Rivista

• Amino acids (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1. INFM, Dipartimento di Fisica, Università di Genova, Genova, Italy. 2. Istituto di Bioimmagini e Fisiologia Molecolare, CNR, Sezione di Genova, Genova, Italy. (literal)

Titolo

• Immunocytochemical study by two photons fluorescence microscopi of the distribution of GABAA receptor subunits in rat cerebellar granule cells in culture. (literal)

Abstract

• An immunocytochemical investigation of the expression of alpha(1), alpha(6), beta(2/3), gamma(2) and delta subunits was performed on rat cerebellum granule cells in culture by the two photon microscopy technique.The first four subunits appear to be expressed abundantly in these cells, whereas the delta one seems to be expressed at a lower level. Another major difference in the distribution of these subunits is that whereas alpha(6), beta(2/3) and gamma(2) appear only on plasma membranes alpha(1) and delta are present mainly in the cell bodies cytoplasm. Still another difference was found in that the presence of gamma(2) on neurites is \"polarized\", preferentially labelling neurites with the appearance of dendrites. The subunits alpha(6) and beta(2/3) appear to label all types of neurites, with beta(2/3) being by far the most heavily expressed subunit type. A final distinct characteristic is that alpha(6) and, even more, gamma(2) appear to accumulate in the cytoplasmic domains immediately below the cone of emergence of neurites. This suggests a conspicuous transport of such subunits from the site of synthesis in the cell body to the site of final expression in the neurites (dendrites and axon terminals). (literal)

Prodotto di

• Institute of molecular bioimaging and physiology (IBFM) (Istituto)

Autore CNR

• AROLDO CUPELLO (Unità di personale interno)

Insieme di parole chiave

• Keywords of "Immunocytochemical study by two photons fluorescence microscopi of the distribution of GABAA receptor subunits in rat cerebellar granule cells in culture." (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute of molecular bioimaging and physiology (IBFM) (Istituto)

Autore CNR di

• AROLDO CUPELLO (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Amino acids (Rivista)

Insieme di parole chiave di

• Keywords of "Immunocytochemical study by two photons fluorescence microscopi of the distribution of GABAA receptor subunits in rat cerebellar granule cells in culture." (Insieme di parole chiave)