The combined disruption of microfilaments and microtubules affects the distribution and function of GABA-A receptors in rat cerebellum granule cells in culture. (Articolo in rivista)

Type

• Prodotto della ricerca (Classe)
• Articolo in rivista (Classe)

Label

• The combined disruption of microfilaments and microtubules affects the distribution and function of GABA-A receptors in rat cerebellum granule cells in culture. (Articolo in rivista) (literal)

Anno

• 2004-01-01T00:00:00+01:00 (literal)

Alternative label

• Luccardini C. 1, Casagrande S. 2, Cupello A. 1, Pellistri F. 2, Ramoino P. 3, Robello M. 2 (2004)
  The combined disruption of microfilaments and microtubules affects the distribution and function of GABA-A receptors in rat cerebellum granule cells in culture.
  in Neuroscience letters (Print)
  (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#autori

• Luccardini C. 1, Casagrande S. 2, Cupello A. 1, Pellistri F. 2, Ramoino P. 3, Robello M. 2 (literal)

Pagina inizio

• 25 (literal)

Pagina fine

• 28 (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#numeroVolume

• 359 (literal)

Rivista

• Neuroscience letters (Rivista)

Note

• ISI Web of Science (WOS) (literal)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#affiliazioni

• 1. Bioimaging and Molecular Physiology Institute, CNR, Genoa, Italy 2. INFM and Department of Physics, University of Genoa, Genoa, Italy 3. Department for the Study of Territory and its Resources, University of Genoa, Genoa, Italy (literal)

Titolo

• The combined disruption of microfilaments and microtubules affects the distribution and function of GABA-A receptors in rat cerebellum granule cells in culture. (literal)

Abstract

• The role of the microfilaments and microtubules cytoskeleton in the stability of the subcellular distribution and function of GABAA receptors has been studied in rat cerebellar granule cells in culture. The disruption of either the microfilaments or the microtubules structures did not result in detectable changes in the receptors distribution, as assessed by immunocytochemistry, or in their function, as assessed by the whole-cell patch-clamp approach. A distinct disruption of both the subcellular distribution and the function of the GABAA receptors was found only if both microfilaments and microtubules were destroyed. The results suggest that, in the short term, the plasma membrane localization/stabilization and function of these receptors in granule cells are largely independent from microfilaments and microtubules individually, although they obviously depend on the presence of an organized cellular framework. (literal)

Prodotto di

• Institute of molecular bioimaging and physiology (IBFM) (Istituto)

Autore CNR

• AROLDO CUPELLO (Unità di personale interno)

Insieme di parole chiave

• Parole chiave di "The combined disruption of microfilaments and microtubules affects the distribution and function of GABA-A receptors in rat cerebellum granule cells in culture." (Insieme di parole chiave)

Incoming links:

Prodotto

• Institute of molecular bioimaging and physiology (IBFM) (Istituto)

Autore CNR di

• AROLDO CUPELLO (Unità di personale interno)

Http://www.cnr.it/ontology/cnr/pubblicazioni.owl#rivistaDi

• Neuroscience letters (Rivista)

Insieme di parole chiave di

• Parole chiave di "The combined disruption of microfilaments and microtubules affects the distribution and function of GABA-A receptors in rat cerebellum granule cells in culture." (Insieme di parole chiave)