http://www.cnr.it/ontology/cnr/individuo/modulo/ID8529
Target molecolari, modelli preclinici ed immunoterapia in Oncologia (ME.P03.015.001)
- Type
- Label
- Target molecolari, modelli preclinici ed immunoterapia in Oncologia (ME.P03.015.001) (literal)
- Prodotto
- Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- The human topoisomerase 1B Arg634Ala mutation results in camptothecin resistance and loss of inter-domain motion correlation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Minimal residual disease as biomarker for optimal biologic dosing of ARA-C in patients with acute myeloid leukemia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Full-haplotype mismatched hematopoietic stem cell transplantation in patients with high risk hematological malignancies. (Abstract/Poster in convegno) (Prodotto della ricerca)
- Mutations of human DNA topoisomerase I at poly (ADP-ribose) binding sites: Modulation of camptothecin activity by ADP-ribose polymers (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- NK cells and T cells cooperate during the clinical course of colorectal cancer (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- HLA-DRB1*03:01 AND HLA-DRB1*11:01 ALLELES ARE ASSOCIATED WITH AN INCREASED RISK OF BREAST CANCER IN ITALIAN INDIVIDUALS (Articolo in rivista) (Prodotto della ricerca)
- Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Pharmacological inhibition of Notch1 and EGFR signaling differently affect cell growth and survival of core and peritumoral glioblastoma-derived stem cells (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- T-cell responses to peptide fragments of the BK virus T antigen: implications for cross-reactivity of immune response to JC virus (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Toxic epidermal necrolysis in patients with malignancies [1] (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Administration of a polyvalent mechanical bacterial lysate to elderly patients with COPD: Effects on circulating T, B and NK cells. (Articolo in rivista) (Prodotto della ricerca)
- High Nitric Oxide production, secondary to high inducible-nitric oxide synthase expression, is essential in regulating tumor initiating properties of colon cancer stem cells. (Abstract/Poster in convegno) (Prodotto della ricerca)
- Serum glucocorticoid inducible kinase (SGK)-1 protects endothelial cells against oxidative stress and apoptosis induced by hyperglycaemia. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Pivotal Role of PDGFR alpha in anti-Notch1 and EGFR Resistant Cancer Stem Cells Derived from Peritumor Tissue of Glioblastoma Multiforme. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- LINE-1 retrotransposon copies are amplified during murine early embryo development. (Articolo in rivista) (Prodotto della ricerca)
- Highly electroconductive multiwalled carbon nanotubes as potentially useful tools for modulating calcium balancing in biological environments. (Articolo in rivista) (Prodotto della ricerca)
- High sensitivity of flow cytometry improves detection of occult leptomeningeal disease in acute lymphoblastic leukemia and lymphoblastic lymphoma. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Interaction between natural compounds and human topoisomerase i (Articolo in rivista) (Prodotto della ricerca)
- A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- NF-kB IS ACTIVATED IN RESPONSE TO TEMOZOLOMIDE AND CONFERS PROTECTION AGAINST DRUG-INDUCED CELL GROWTH INHIBITION (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- Forskolin promotes neuronal differentiation on human Whartons jelly mesenchymal stem cells (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- Effetto stimolatorio dellolio essenziale di Eucalipto sullimmunità innata cellulare (Contributo in atti di convegno) (Prodotto della ricerca)
- Clinical impact of programmed cell death ligand 1 expression in colorectal cancer. (Articolo in rivista) (Prodotto della ricerca)
- Tumor infiltration by Fc gamma RIII (CD16)+ myeloid cells is associated with improved survival in patients with colorectal carcinoma (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- A pilot study on human Whartons jelly mesenchymal stem cells induced to neural differentiation (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- Single Mutation in the Linker Domain Confers Protein Flexibility and Camptothecin Resistance to Human Topoisomerase I (Articolo in rivista) (Prodotto della ricerca)
- PDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Dermal apoptosis is not influenced by the severity of clinical conditions in burned patients (Articolo in rivista) (Prodotto della ricerca)
- Cytokine Response to Ischemia/Reperfusion Injury in an Ex Vivo Perfused Porcine Liver Model (Articolo in rivista) (Prodotto della ricerca)
- Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Atrial Natriuretic Peptide: a Magic Bullet for Cancer Therapy Targeting Wnt Signaling and Cellular pH Regulators (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in Inflammatory Bowel Disease and sporadic colorectal cancer (Articolo in rivista) (Prodotto della ricerca)
- ASSOCIATIONS BETWEEN GENES FOR KILLER IMMUNOGLOBULIN-LIKE RECEPTORS (KIR) AND THEIR HLA-C LIGANDS IN PATIENTS WITH COLORECTAL TUMORS (Abstract in rivista) (Prodotto della ricerca)
- Melanoma Cells Inhibit NK Cell Functions-Letter (Articolo in rivista) (Prodotto della ricerca)
- Extensive toxic epidermal necrolysis following brentuximab vedotin administration (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- CONTRIBUTION OF KIR AND FCGR3A RECEPTORS GENE CONTENT IN NK MODULATION OF IMMUNE RESPONSE TO COLORECTAL MALIGNANT CELLS (Abstract in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1105)
- A SURVEY OF AUTOANTIBODIES TO SELF ANTIGENS IN GRAVES' DISEASE PATIENTS WITH THYROID-ASSOCIATED OPHTHALMOPATHY (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- New Molecular Biomarkers Candidates for the Development of Multiparametric Platforms for Hepatocellular carcinoma Diagnosis, Prognosis and Personalised Therapy (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
- Treatment of doxorubicin resistant MCF7/Dx cells with nitric oxide causes histone glutathionylation and reversal of drug resistance. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Antitumor effects of the benzophenanthridine alkaloid sanguinarine in a rat syngeneic model of colorectal cancer. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Effects of carbonaceous nanoparticles from low-emission and older diesel engines on human skin cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- The Cystine/Cysteine Cycle and GSH Are Independent and Crucial Antioxidant Systems in Malignant Melanoma Cells and Represent Druggable Targets. (Articolo in rivista) (Prodotto della ricerca)
- TCTP is a critical survival factor that protects cancer cells from oxidative stress-induced cell-death. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Gene expression Profiling of embryonic human neural stem cells and dopaminergic neurons from adult human substantia nigra (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Liver stem cells and possible clinical applications. (Articolo in rivista) (Prodotto della ricerca)
- MicroRNA-155 Targets the SKI Gene in Human Melanoma Cell Lines (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- The cyclin-dependent kinase inhibitor PHA-848125 suppresses the in vitro growth of human melanomas sensitive or resistant to temozolomide, and shows synergistic effects in combination with this triazene compound (Articolo in rivista) (Prodotto della ricerca)
- Human endogenous retroviruses and ADHD (Articolo in rivista) (Prodotto della ricerca)
- CD44-targeting for antitumor drug delivery: a new SN-38-hyaluronan bioconjugate for locoregional treatment of peritoneal carcinomatosis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genetic immunization with CDR3-based fusion vaccine confers protection and long-term tumor-free survival in a mouse model of lymphoma. (Articolo in rivista) (Prodotto della ricerca)
- Inhibitory effects of gangliosides and cyclosporine on lymphocyte activation: Analysis of cytokine gene mRNA transcripts (Articolo in rivista) (Prodotto della ricerca)
- CD44 cross-linking on peripheral blood t lymphocytes induces th1 cytokines production (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
- Thymosin alfa1 Activates Complement Receptor-Mediated Phagocytosis in Human Monocyte-Derived Macrophages (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Down-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125. (Articolo in rivista) (Prodotto della ricerca)
- CD44 ligation on peripheral blood polymorphonuclear cells induces interleukin-6 production (Articolo in rivista) (Prodotto della ricerca)
- More than two different bacterial species isolated from blood of toxic epidermal necrolysis patients significantly increase mortality (Articolo in rivista) (Prodotto della ricerca)
- High Myeloperoxidase Positive Cell Infiltration in Colorectal Cancer Is an Independent Favorable Prognostic Factor (Articolo in rivista) (Prodotto della ricerca)
- High Frequency of CD8 Positive Lymphocyte Infiltration Correlates with Lack of Lymph Node Involvement in Early Rectal Cancer (Articolo in rivista) (Prodotto della ricerca)
- In vitro effect of hyperthermia on natural cell-mediated cytotoxicity. (Articolo in rivista) (Prodotto della ricerca)
- Central nervous system involvement in adult acute lymphoblastic leukemia: diagnostic tools, prophylaxis, and therapy. (Articolo in rivista) (Prodotto della ricerca)
- GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- HLA Class II Antigen Expression in Colorectal Carcinoma Tumors as a Favorable Prognostic Marker (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Peroxiredoxin 6, a Novel Player in the Pathogenesis of Diabetes (Articolo in rivista) (Prodotto della ricerca)
- Role of Flexibility in Protein-DNA-Drug Recognition: The Case of Asp677Gly-Val703Ile Topoisomerase Mutant Hypersensitive to Camptothecin. (Articolo in rivista) (Prodotto della ricerca)
- Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing plasmodium parasites based on enzyme activity measurement (Articolo in rivista) (Prodotto della ricerca)
- Specific detection of topoisomerase I from the malaria causing P. falciparum parasite using isothermal rolling circle amplification. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Replacement of the Human Topoisomerase Linker Domain with the Plasmodial Counterpart Renders the Enzyme Camptothecin Resistant (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Codice
- Anno di chiusura previsto
- 2017-01-01T00:00:00+01:00 (literal)
- Istituto esecutore
- Abstract
- Uno degli approcci più promettenti per sviluppare strumenti diagnostici/prognostici più specifici è quello di combinare diversi indicatori positivi o negativi in piattaforme multiparametriche per il rilevamento simultaneo di più markers. Lo sviluppo di tali piattaforme, per il quale è essenziale la scoperta e validazioni di nuovi biomarcatori, può essere di utilità, in campo oncologico, non solo per la diagnosi precoce, la stadiazione e la prognosi dei tumori, ma anche per progettare terapie personalizzate target-specifiche.
L'attività del modulo si focalizza sui meccanismi coinvolti nell'oncogenesi e nella farmaco-resistenza, sulle relazioni tra processi infiammatori e neoplasie e sulla messa a punto di interventi preventivi/terapeutici innovativi. Principali obiettivi
1) Studio di nuovi bersagli molecolari, diagnostici e terapeutici e identificazione di nuovi biomarcatori;
2) Sviluppo di strategie terapeutiche/diagnostiche innovative e piattaforme di \"drug delivery\";
3) Studi sul ruolo del microambiente tumorale nella trasformazione neoplastica.
L'obiettivo finale è il trasferimento alla clinica dei risultati ottenuti da ricerca biomolecolare e sperimentazione preclinica (literal)
- Nome
- Target molecolari, modelli preclinici ed immunoterapia in Oncologia (literal)
- Descrizione
- Modulo di
- Gestore
Incoming links:
- Istituto esecutore di
- Gestore di
- Prodotto di
- A pilot study on human Whartons jelly mesenchymal stem cells induced to neural differentiation (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- TCTP is a critical survival factor that protects cancer cells from oxidative stress-induced cell-death. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Treatment of doxorubicin resistant MCF7/Dx cells with nitric oxide causes histone glutathionylation and reversal of drug resistance. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Antitumor effects of the benzophenanthridine alkaloid sanguinarine in a rat syngeneic model of colorectal cancer. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Effects of carbonaceous nanoparticles from low-emission and older diesel engines on human skin cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- CD44-targeting for antitumor drug delivery: a new SN-38-hyaluronan bioconjugate for locoregional treatment of peritoneal carcinomatosis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- MicroRNA-155 Targets the SKI Gene in Human Melanoma Cell Lines (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Liver stem cells and possible clinical applications. (Articolo in rivista) (Prodotto della ricerca)
- The Cystine/Cysteine Cycle and GSH Are Independent and Crucial Antioxidant Systems in Malignant Melanoma Cells and Represent Druggable Targets. (Articolo in rivista) (Prodotto della ricerca)
- Highly electroconductive multiwalled carbon nanotubes as potentially useful tools for modulating calcium balancing in biological environments. (Articolo in rivista) (Prodotto della ricerca)
- LINE-1 retrotransposon copies are amplified during murine early embryo development. (Articolo in rivista) (Prodotto della ricerca)
- NF-kB IS ACTIVATED IN RESPONSE TO TEMOZOLOMIDE AND CONFERS PROTECTION AGAINST DRUG-INDUCED CELL GROWTH INHIBITION (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- Forskolin promotes neuronal differentiation on human Whartons jelly mesenchymal stem cells (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
- Effetto stimolatorio dellolio essenziale di Eucalipto sullimmunità innata cellulare (Contributo in atti di convegno) (Prodotto della ricerca)
- New Molecular Biomarkers Candidates for the Development of Multiparametric Platforms for Hepatocellular carcinoma Diagnosis, Prognosis and Personalised Therapy (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
- Tumor infiltration by Fc gamma RIII (CD16)+ myeloid cells is associated with improved survival in patients with colorectal carcinoma (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Gene expression Profiling of embryonic human neural stem cells and dopaminergic neurons from adult human substantia nigra (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genetic immunization with CDR3-based fusion vaccine confers protection and long-term tumor-free survival in a mouse model of lymphoma. (Articolo in rivista) (Prodotto della ricerca)
- The cyclin-dependent kinase inhibitor PHA-848125 suppresses the in vitro growth of human melanomas sensitive or resistant to temozolomide, and shows synergistic effects in combination with this triazene compound (Articolo in rivista) (Prodotto della ricerca)
- Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Down-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125. (Articolo in rivista) (Prodotto della ricerca)
- Administration of a polyvalent mechanical bacterial lysate to elderly patients with COPD: Effects on circulating T, B and NK cells. (Articolo in rivista) (Prodotto della ricerca)
- Clinical impact of programmed cell death ligand 1 expression in colorectal cancer. (Articolo in rivista) (Prodotto della ricerca)
- Pharmacological inhibition of Notch1 and EGFR signaling differently affect cell growth and survival of core and peritumoral glioblastoma-derived stem cells (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- A SURVEY OF AUTOANTIBODIES TO SELF ANTIGENS IN GRAVES' DISEASE PATIENTS WITH THYROID-ASSOCIATED OPHTHALMOPATHY (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- In vitro effect of hyperthermia on natural cell-mediated cytotoxicity. (Articolo in rivista) (Prodotto della ricerca)
- Atrial Natriuretic Peptide: a Magic Bullet for Cancer Therapy Targeting Wnt Signaling and Cellular pH Regulators (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in Inflammatory Bowel Disease and sporadic colorectal cancer (Articolo in rivista) (Prodotto della ricerca)
- Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Extensive toxic epidermal necrolysis following brentuximab vedotin administration (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- CONTRIBUTION OF KIR AND FCGR3A RECEPTORS GENE CONTENT IN NK MODULATION OF IMMUNE RESPONSE TO COLORECTAL MALIGNANT CELLS (Abstract in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1105)
- ASSOCIATIONS BETWEEN GENES FOR KILLER IMMUNOGLOBULIN-LIKE RECEPTORS (KIR) AND THEIR HLA-C LIGANDS IN PATIENTS WITH COLORECTAL TUMORS (Abstract in rivista) (Prodotto della ricerca)
- Melanoma Cells Inhibit NK Cell Functions-Letter (Articolo in rivista) (Prodotto della ricerca)
- Cytokine Response to Ischemia/Reperfusion Injury in an Ex Vivo Perfused Porcine Liver Model (Articolo in rivista) (Prodotto della ricerca)
- Dermal apoptosis is not influenced by the severity of clinical conditions in burned patients (Articolo in rivista) (Prodotto della ricerca)
- CD44 cross-linking on peripheral blood t lymphocytes induces th1 cytokines production (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
- Pivotal Role of PDGFR alpha in anti-Notch1 and EGFR Resistant Cancer Stem Cells Derived from Peritumor Tissue of Glioblastoma Multiforme. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- High Nitric Oxide production, secondary to high inducible-nitric oxide synthase expression, is essential in regulating tumor initiating properties of colon cancer stem cells. (Abstract/Poster in convegno) (Prodotto della ricerca)
- PDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Peroxiredoxin 6, a Novel Player in the Pathogenesis of Diabetes (Articolo in rivista) (Prodotto della ricerca)
- High Frequency of CD8 Positive Lymphocyte Infiltration Correlates with Lack of Lymph Node Involvement in Early Rectal Cancer (Articolo in rivista) (Prodotto della ricerca)
- Central nervous system involvement in adult acute lymphoblastic leukemia: diagnostic tools, prophylaxis, and therapy. (Articolo in rivista) (Prodotto della ricerca)
- High Myeloperoxidase Positive Cell Infiltration in Colorectal Cancer Is an Independent Favorable Prognostic Factor (Articolo in rivista) (Prodotto della ricerca)
- Mutations of human DNA topoisomerase I at poly (ADP-ribose) binding sites: Modulation of camptothecin activity by ADP-ribose polymers (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- The human topoisomerase 1B Arg634Ala mutation results in camptothecin resistance and loss of inter-domain motion correlation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Replacement of the Human Topoisomerase Linker Domain with the Plasmodial Counterpart Renders the Enzyme Camptothecin Resistant (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Specific detection of topoisomerase I from the malaria causing P. falciparum parasite using isothermal rolling circle amplification. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing plasmodium parasites based on enzyme activity measurement (Articolo in rivista) (Prodotto della ricerca)
- Role of Flexibility in Protein-DNA-Drug Recognition: The Case of Asp677Gly-Val703Ile Topoisomerase Mutant Hypersensitive to Camptothecin. (Articolo in rivista) (Prodotto della ricerca)
- Single Mutation in the Linker Domain Confers Protein Flexibility and Camptothecin Resistance to Human Topoisomerase I (Articolo in rivista) (Prodotto della ricerca)
- Thymosin alfa1 Activates Complement Receptor-Mediated Phagocytosis in Human Monocyte-Derived Macrophages (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- HLA Class II Antigen Expression in Colorectal Carcinoma Tumors as a Favorable Prognostic Marker (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- More than two different bacterial species isolated from blood of toxic epidermal necrolysis patients significantly increase mortality (Articolo in rivista) (Prodotto della ricerca)
- CD44 ligation on peripheral blood polymorphonuclear cells induces interleukin-6 production (Articolo in rivista) (Prodotto della ricerca)
- Inhibitory effects of gangliosides and cyclosporine on lymphocyte activation: Analysis of cytokine gene mRNA transcripts (Articolo in rivista) (Prodotto della ricerca)
- Human endogenous retroviruses and ADHD (Articolo in rivista) (Prodotto della ricerca)
- A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Interaction between natural compounds and human topoisomerase i (Articolo in rivista) (Prodotto della ricerca)
- High sensitivity of flow cytometry improves detection of occult leptomeningeal disease in acute lymphoblastic leukemia and lymphoblastic lymphoma. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- T-cell responses to peptide fragments of the BK virus T antigen: implications for cross-reactivity of immune response to JC virus (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Toxic epidermal necrolysis in patients with malignancies [1] (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Full-haplotype mismatched hematopoietic stem cell transplantation in patients with high risk hematological malignancies. (Abstract/Poster in convegno) (Prodotto della ricerca)
- NK cells and T cells cooperate during the clinical course of colorectal cancer (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- HLA-DRB1*03:01 AND HLA-DRB1*11:01 ALLELES ARE ASSOCIATED WITH AN INCREASED RISK OF BREAST CANCER IN ITALIAN INDIVIDUALS (Articolo in rivista) (Prodotto della ricerca)
- Minimal residual disease as biomarker for optimal biologic dosing of ARA-C in patients with acute myeloid leukemia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Serum glucocorticoid inducible kinase (SGK)-1 protects endothelial cells against oxidative stress and apoptosis induced by hyperglycaemia. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- http://www.cnr.it/ontology/cnr/individuo/prodotto/ID301720
- Modulo
- Descrizione di
