Determinazione della struttura tridimensionale di biomolecole complesse con tecniche spettroscopiche e cristallografiche (PM.P01.022.001)

Type

• Modulo (Classe)

Label

• Determinazione della struttura tridimensionale di biomolecole complesse con tecniche spettroscopiche e cristallografiche (PM.P01.022.001) (literal)

Prodotto

• A new RNasesheds light on the RNase/angiogenin subfamily from zebrafish (Articolo in rivista) (Prodotto della ricerca)
• (In)organic anions as carbonic anhydrase inhibitors (Articolo in rivista) (Prodotto della ricerca)
• Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Expression,purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacteriumtuberculosis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Improving Protein Crystal Quality by the Without-Oil Microbatch Method: Crystallization and Preliminary X-ray Diffraction Analysis of Glutathione Synthetase from Pseudoalteromonas haloplanktis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbonic anhydraseinhibitors: X-ray crystallographic studies for the binding of N-substitutedbenzenesulfonamides to human isoform II (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• -RAY CRYSTALLOGRAPHY OF CARBONIC ANHYDRASE INHIBITORS AND ITS IMPORTANCE IN DRUG DESIGN. In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• A novel member of the protein disulfide oxidoreductase family from Aeropyrum pernix K1: structure, function and electrostatics. (Articolo in rivista) (Prodotto della ricerca)
• Structural characterization of ferric hemoglobins from three Antarctic fish species of the suborder Notothenioidei (Articolo in rivista) (Prodotto della ricerca)
• Functional and structural features of the oxyanion hole in a thermophilic esterase from Alicyclobacillus acidocaldarius (Articolo in rivista) (Prodotto della ricerca)
• Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• combined femtosecond fluorescence and TD-DFT study of uracil derivatives in aqueous solution Femtochemistry VII Fundamental Ultrafast Processes (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Inhibition of the R1 fragment of the cadmium-containing zeta-class carbonic anhydrase from the diatom Thalassiosira weissflogii with anions. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Dynamics and stability of amyloid-like steric zipper assemblies with hydrophobic dry interfaces. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Multiple catalytically active thioredoxin folds: a winning strategy for many functions. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Drug design studies of the novel antitumor targets carbonic anhydrase IX and XII (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish (Articolo in rivista) (Prodotto della ricerca)
• Structure and flexibility in cold-adapted iron superoxide dismutases: the case of the enzyme isolated from Pseudoalteromonas haloplanktis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• STRUCTURAL CHARACTERIZATION OF HUMAN CARBONIC ANHYDRASE (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• STRUCTURAL CHARACTERIZATION OF CARBONIC ANHYDRASE INHIBITORS INCORPORATING NEW METAL BINDING FUNCTIONALITIES (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• resolution X-ray structure of the complex of human alpha thrombin with a modified thrombin binding aptamer (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• CD and NMR conformational studies of a peptide encompassing the Mid Loop interface of Ship2-Sam (Articolo in rivista) (Prodotto della ricerca)
• Carbonic anhydrase inhibitors: bioreductive nitro-containing sulfonamides with selectivity for targeting the tumor associated isoforms IX and XII. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Heterotypic Sam-Sam association between Odin-Sam1 and Arap3-Sam: binding affinity and structural insights. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Solution structure of the first Sam domain of Odin and binding studies with the EphA2 receptor. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• HE CRYSTAL STRUCTURE OF A FERULOYL ESTERASE FROM THE PSYCHROPHILIC BACTERIUM PSEUDOALTEROMONAS HALOPLANKTIS TAC125 (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• An order-disorder transition plays a role in switching off the Root effect in fish hemoglobins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A combined Raman microscopy and X-ray crystallography approach to study protein single crystals (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• CRYSTAL STRUCTURE OF A PROTEIN DISULFIDE OXIDOREDUCTASE FROM AEROPYRUM PERNIX K1 (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• DEVELOPMENTS IN THE DESIGN OF ANTITUMOR CARBONIC ANHYDRASE INHIBITORS (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Structure and dimerization of the teleost transmembrane immunoglobulin region (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structural characterization of a thermostable thioredoxin reductase isolated from Sulfolobus solfataricus (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• 3D Structure of Archaeal Elongation Factors by Synchrotron Radiation (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• 3D domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structural insights into and activity analysis of the antimicrobial peptide myxinidin (Articolo in rivista) (Prodotto della ricerca)
• Towards the understanding the structural bases of collagen triple helix stability (Monografia o trattato scientifico) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1401)
• Thrombin-aptamer recognition: a revealed ambiguity (Articolo in rivista) (Prodotto della ricerca)
• Occurrence and formation of endogenous histidine hexa-coordination incold-adapted hemoglobins. IUBMB Life (Articolo in rivista) (Prodotto della ricerca)
• Protonation of histidine 55 affects the oxygen access to heme in the alpha chain of the hemoglobin from the Antarctic fish Trematomus bernacchii (Articolo in rivista) (Prodotto della ricerca)
• 3D Structural Characterization of a Thermostable Thioredoxin Reductase Isolated from Sulfolobus solfataricus (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Stereochemistry, formation and reactivity of hemichromes in Antarctic fish hemoglobins (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• A novel method for detection of Se-Met inclusion into protein crystals via Raman microscopy (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Physico-chemical effects influencing the rate of the dissociative electron transfer in polypeptide systems. (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• CARBONIC ANHYDRASE INHIBITORS: HYPOXIA-ACTIVATABLE SULFONAMIDES INCORPORATING DISULFIDE BONDS THAT TARGET THE TUMOR-ASSOCIATED ISOFORM I (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Raman-assisted biocrystallography” Gordon Conference: Vibrational Spectroscpy (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Raman-assisted biocrystallography of metal-proteins (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• THE CRYSTAL STRUCTURE OF HCA I/TOPIRAMATE COMPLEX PROVIDES USEFUL INSIGHTS INTO RATIONAL DRUG DESIGN OF ANTI-OBESITY DRUGS (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Crystal structure of the ribosome inactivating protein PD-L3 from Phytolacca dioica (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• bases of M. tuberculosis daughter cell separation (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• STRUCTURAL AND FUNCTIONAL INSIGHTS INTO BCP4: COMPONENT OF THE ANTIOXIDANT SYSTEM OF SULFOLOBUS SOLFATARICUS (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• KCTD7: a new substrate-specific adaptor for Cul3 involved in Progressive Myoclonic Epilepsy (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Structural and functional characterization of Resuscitatin-Promoting Factors from Mycobacterium tuberculosis (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Dormancy in Mycobacterium tuberculosis: the role of resuscitation-promoting factors (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Linkage between Root effect and hemichrome stability (Contributo in atti di convegno) (Prodotto della ricerca)
• Minimal structural requirements for root effect: Crystal structure of the cathodic hemoglobin isolated from the antarctic fish Trematomus newnesi. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A contribution to the solvation free energy in isotropic and anisotropic polarizable continuum model. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Crystallization and preliminary X-ray crystallographic analysis of the Sulfolobus solfataricus nucleotide-exchange factor 1b (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Correlation between Omega and Psi Dihedral Angles in Protein Structures (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Minimal structural requirements for Root effect: Crystal structure of the cathodic hemoglobin isolated from the antarctic fish Trematomus newnesi (Articolo in rivista) (Prodotto della ricerca)
• Design and NMR studies of cyclic peptides targeting the N-terminal domain of the protein tyrosine phosphatase YopH. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbonic anhydrase inhibitors: hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The first crystal structure of a thioacylenzyme intermediate in the ALDH family: New coenzyme conformation and relevance to catalysis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A Parameter Free Quantum Mechanical Approach to the Calculation of Electron Transfer Rates for Large Systems in Solution (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Dissociative Electron Transfer in Donor-Peptide-Acceptor Systems: Results for Kinetic Parameters from a Density Functional/Polarizable Continuum Model (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 2-Substituted Estradiol Bis-sulfamates, Multitargeted Antitumor Agents: Synthesis, In Vitro SAR, Protein Crystallography, and In Vivo Activity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Open interface and large quaternary structure movements in 3D domain swapped proteins: insights from molecular dynamics simulations of the C-terminal swapped dimer of ribonuclease A (Articolo in rivista) (Prodotto della ricerca)
• A crevice adjoining the ribosome tunnel: Hints for cotranslational folding. (Articolo in rivista) (Prodotto della ricerca)
• Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies. (Articolo in rivista) (Prodotto della ricerca)
• Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Very late onset in ataxia oculomotor apraxia type I. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The Root effect - a structural and evolutionary perspective. (Articolo in rivista) (Prodotto della ricerca)
• Approximate values for force constant and wave number associated with a low-frequency concerted motion in proteins can be evaluated by a comparison of X-ray structures (Articolo in rivista) (Prodotto della ricerca)
• Carbonic anhydrase inhibitors: binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties (Articolo in rivista) (Prodotto della ricerca)
• A novel method for detection of Se-Met inclusion into protein crystals via Raman microscopy (Articolo in rivista) (Prodotto della ricerca)
• Crystallization, preliminary X-ray diffraction studies and Raman microscopy of the major hemoglobin from the sub-Antarctic fish Eleginops maclovinus in the carbomonoxy form. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Hydrophobic Substituents of the Phenylmethylsulfamide Moiety Can Be Used for the Development of New Selective Carbonic Anhydrase Inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Crystallization and preliminary x-ray diffraction studies of a protein disulfide oxidoreductase from Aeropyrum pernix K1 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Five human phenylalanine hydroxylase proteins identified in mild hyperphenylalaninemia patients are disease-causing variants (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• In HspA from Helicobacter pylori vicinal disulfide bridges are a key determinant of domain B structure (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Conformational states and association mechanism of Yersinia pestis Caf1 subunits. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of Thr200 and Gln92 for obtaining tight-binding inhibitors. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Recent Advances in Research on the Most Novel Carbonic Anhydrases, CA XIII and XV (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Femtosecond study on the isomerization dynamics of NK88: I. Ground state dynamics after photoexcitation (Articolo in rivista) (Prodotto della ricerca)
• Hydroxamate represents a versatile zinc binding group for the development of new carbonic anhydrase inhibitors (Articolo in rivista) (Prodotto della ricerca)
• Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II \"selective\" inhibitor celecoxib. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Insight into Ribonuclease A Domain Swapping by Molecular Dynamics Unfolding Simulations (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The importance of dynamic effects on the enzyme activity: X-ray structure and molecular dynamics of onconase. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Spectroscopic and crystallographic characterization of hemichromes in tetrameric hemoglobins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A novel method for detection of Se-Met inclusion into protein crystals via Raman microscopy (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structural characterization of the oxidation pathway of antarctic fish hemoglobins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structural determinats of M. tuberculosis agglutination guided by heparin binding hemagglutinin (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Polyproline helices in protein structures: a statistical survey (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• CARBONIC ANHYDRASE INHIBITORS: X-RAY CRYSTALLOGRAPHIC STUDIES FOR THE BINDING OF 5-AMINO-1,3,4-THIADIZOLE-2-SULFONAMIDE AND 5-(4-AMINO-3-CHLORO-5-FLUOROPHENYLSULFONAMIDO)-1,3,4-THIADIAZOLE-2-SULFONAMIDE TO HUMAN ISOFORM II (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Insights on a new PDI-like family: structural and functional analysis of a protein disulfide oxidoreductase from the bacterium Aquifex aeolicus. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish (Articolo in rivista) (Prodotto della ricerca)
• Exploring the catalytic mechanism of the first dimeric Bcp: Functional, structural and docking analyses of Bcp4 from Sulfolobus solfataricus. (Articolo in rivista) (Prodotto della ricerca)
• The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex. (Articolo in rivista) (Prodotto della ricerca)
• Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis (Articolo in rivista) (Prodotto della ricerca)
• Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the peptidoglycan binding region of the Ser/Thr kinase PrkC from Staphylococcus aureus (Articolo in rivista) (Prodotto della ricerca)
• Biochemical characterization of CA IX, one of the most active Carbonic Anhydrase isozymes. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Crystallization and Preliminary X-Ray Crystallographic Analysis of the Complex of Human Alpha Thrombin With A Modified Thrombin Binding Aptamer (Articolo in rivista) (Prodotto della ricerca)
• Correlation between Raman and X-ray crystallography data of (Pro-Pro-Gly)10 (Articolo in rivista) (Prodotto della ricerca)
• Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (Articolo in rivista) (Prodotto della ricerca)
• Atomic resolution (1.1 A) structure the of Ribosome-Inactivating Protein PD-L4 from Phytolacca dioica L. leaves (Articolo in rivista) (Prodotto della ricerca)
• Molecular dynamics studies of the P pilus rod subunit PapA (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Ribosome's mode of function: myths, facts and recent results (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Biochemical characterisation of the D60A mutant of the elongation factor 1 from the archaeon Sulfolobus solfataricus (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Comment on Microfibrillar structure of type I collagen in situ by Orgel et al. (2006), Proc. Natl Acad. Sci. USA, 103, 9001-9005 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Raman-assisted Biocrystallography. Applications to metal proteins (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Monitoring the prepration of protein derivative crystals via Raman-microscopy (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• A CUL3-DERIVED PEPTIDE BINDING DIFFERENT MEMBERS OF THE KCTD FAMILY (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• PRELIMINARY CHARACTERIZATION OF BRUCELLA SUIS HYSTIDINOL DEHYDROGENASE (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Structural and functional characterization of the Cul3 adaptor RENKCTD11 (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Crystal structure of an S-formylglutathione hydrolase from pseudoalteromonas haloplanktis TAC125. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structural and functional characterisation of hemoglobins of Eleginops maclovinus, a sub-Antarctic notothenioid fish Proteine (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Recent advances in structural studies of the carbonic anhydrase family: the crystal structure of human CA IX and CA XIII. (Articolo in rivista) (Prodotto della ricerca)
• STRUCTURAL ANALYSIS OF THE TRANSCRIPTIONAL REGULATOR BALD16 FROM SULFOLOBUS SOLFATARICUS (Contributo in atti di convegno) (Prodotto della ricerca)
• Carbonic anhydrase IX: Biochemical and crystallographic characterization of a novel antitumor target. (Articolo in rivista) (Prodotto della ricerca)
• Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation (Articolo in rivista) (Prodotto della ricerca)
• Understanding the Structural Bases of Collagen Triple Helix Stability (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Role of side chains in collagen triple helix stabilization and partner recognition (Articolo in rivista) (Prodotto della ricerca)
• Bis-Histidyl adducts in tetrameric hemoglobins (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• ADVANCES IN THE INHIBITORY AND STRUCTURAL INVESTIGATIONS ON CARBONIC ANHYDRASE ISOZYMES XIII AND XV In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Insights Into The Catalytic Mechanism Of The Bcp Family: Functional And Structural Analysis Of Bcp1 From Sulfolobus Sulfataricus (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• DRUG DESIGN OF ANTIOBESITY CARBONIC ANHYDRASE INHIBITORS. In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• A molecular dynamics study of pilin subunits: insights into pilus biogenesis (Contributo in atti di convegno) (Prodotto della ricerca)
• Insight into old and new questions in structural biology by experimental and computational methodologies (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Heterodimeric peptide compounds displaying NGF activity and their use to treat neurodegenerative disorders (Brevetto) (Brevetto)
• Accurate computation of fluorescence spectra in solution: A time-dependent DFT study on the excited states of some uracil derivatives in water and acetonitrile solution (Contributo in atti di convegno) (Prodotto della ricerca)
• Electron Transfer To Flat Peptides (Contributo in atti di convegno) (Prodotto della ricerca)
• Reduction of ferric hemoglobin from Trematomus bernacchii in a partial bis-histidyl state produces a deoxy coordination even when encapsulated into the crystal phase (Articolo in rivista) (Prodotto della ricerca)
• Host-pathogen adhesion at an atomic level. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Root effect also functions modulating the hemichrome stability in tetrameric hemoglobins (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Identification and characterization of a new form of oncosuppressor KCTD11 (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Conformational Study of Self-Asembling Peptides (Contributo in atti di convegno) (Prodotto della ricerca)
• CARBONIC ANHYDRASE INHIBITORS: X-RAY AND MOLECULAR MODELING STUDY FOR THE INTERACTION OF A FLUORESCENT ANTITUMOR SULFONAMIDE WITH ISOZYME II AND IX (Contributo in atti di convegno) (Prodotto della ricerca)
• G-quadruplex DNA recognition by nucleophosmin: New insights from protein dissection (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II. (Articolo in rivista) (Prodotto della ricerca)
• Peptides targeting chemokine receptor CXCR4: Structural behavior and biological binding studies (Articolo in rivista) (Prodotto della ricerca)
• High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: the role of histidine residues in modulating the strength of the root effect (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The crystal structure of the superoxide dismutase from Helicobacter pylori reveals a structured C-terminal extension (Articolo in rivista) (Prodotto della ricerca)
• Exploring the antioxidant system of Sulfolobus solfataricus: structural and functional analysis of peroxiredoxin Bcp1 (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Carbonic Anhydrase inhibitors: bioreductive nitro-containing sulfonamides targeting the tumor-associated isoforms CA IX and XII (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Biophysical and biochemical characterization of a liposarcoma-derived recombinant MnSOD protein acting as an anticancer agent (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• nteractions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor. (Articolo in rivista) (Prodotto della ricerca)
• Unraveling the structural and functional features of an aldolase A mutant involved in the hemolytic anemia and severe rhabdomyolysis reported in a child (Articolo in rivista) (Prodotto della ricerca)
• he role of the hinge loop in domain-swapping: The special case of Bovine seminal Ribonuclease. (Articolo in rivista) (Prodotto della ricerca)
• Lessons from crystals grown in the Advanced Protein Crystallisation Facility for conventional crystallisation applied to structural biology. (Articolo in rivista) (Prodotto della ricerca)
• Evidence for an elongated dimeric structure of heparin-binding haemaglutinin from M. tuberculosis (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Crystallization and preliminary x-ray crystallographic analysis of Sulfolobus solfataricus thioredoxin reductase (Articolo in rivista) (Prodotto della ricerca)
• Multiple binding modes of inhibitors to carbonic anhydrases: How to design specific drugs targeting 15 different isoforms? (Articolo in rivista) (Prodotto della ricerca)
• Investigations of the esterase, phosphatase, and sulfatase activities of the cytosolic mammalian carbonic anhydrase isoforms I, II, and XIII with 4-nitrophenyl esters as substrates (Articolo in rivista) (Prodotto della ricerca)
• Carbonic anhydrase inhibitors: binding of indanesulfonamides to the human isoform II (Articolo in rivista) (Prodotto della ricerca)
• Revival of M. tuberculosis from latency. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• The hemoglobins of fishes living at polar latitudes- Current knowledge on structural adaptations in a challenging environment (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides - Solution and crystallographic studies (Articolo in rivista) (Prodotto della ricerca)
• Antiobesity carbonic anhydrase inhibitors (Articolo in rivista) (Prodotto della ricerca)
• Crystallization and preliminary X-ray diffraction analysis of PD-L1, a highly glycosylated ribosome inactivating protein with DNase activity (Articolo in rivista) (Prodotto della ricerca)
• Functional And Structural Charateristics Of The Oxyanion Hole In A Thermophilic Esterase From Alyciclobacillus Acidocaldarius (Articolo in rivista) (Prodotto della ricerca)
• Insights into the catalytic mechanism of the carbonic anhydrase family from the crystal structure of human isoform (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Atomic resolution (1.1 A) structure of the ribosome-inactivating protein PD-L4 from Phytolacca dioica L. leaves. (Articolo in rivista) (Prodotto della ricerca)
• Crystallization and preliminary X-ray diffraction studies of a psychrophilic iron superoxide dismutase from Pseudoalteromonas haloplanktis (Articolo in rivista) (Prodotto della ricerca)
• Anticancer steroid sulfatase inhibitors: Synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography. (Articolo in rivista) (Prodotto della ricerca)
• Crystallization and preliminary X-ray crystallographic analysis of ligand-free and arginine-bound forms of Thermotoga maritima arginine-binding protein (Articolo in rivista) (Prodotto della ricerca)
• Crystallographic studied of ribosome inactivating proteins (Comunicazione a convegno) (Prodotto della ricerca)
• Gene cloning andprotein expression of ?-glutamyltranspeptidases from Thermus thermophilus and Deinococcus radiodurans: comparison of molecular and structural properties withmesophilic counterparts (Articolo in rivista) (Prodotto della ricerca)
• A novel ErbB2 epitope targeted by humanantitumor immunoagents (Articolo in rivista) (Prodotto della ricerca)
• Molecular dynamics analyses of cross-b-spine steric zipper models: b-sheet twisting and aggregation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbonic Anhydrase Inhibitors: X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Chemical denaturation of the elongation factor 1a isolated from the hyperthermophilic archaeon Sulfolobus solfataricus (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Polyglutamine repeats and beta-helix structure: Molecular dynamics study (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 23S rRNA 2058A-->G alteration mediates ketolide resistance in combination with deletion in L22 (Articolo in rivista) (Prodotto della ricerca)
• A Novel Type of Zinc Finger DNA Binding Domain in the Agrobacterium tumefaciens Transcriptional Regulator Ros (Articolo in rivista) (Prodotto della ricerca)
• Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candidaalbicans and Candida glabrata (Articolo in rivista) (Prodotto della ricerca)

Codice

• PM.P01.022.001 (literal)

Anno di chiusura previsto

• 2016-01-01T00:00:00+01:00 (literal)

Istituto esecutore

• Institute of biostructure and bioimaging (IBB) (Istituto)

Primo anno di attività

• 2005-01-01T00:00:00+01:00 (literal)

Abstract

• La conoscenza della struttura di macromolecole coinvolte nei processi biologici e' un passaggio fondamentale per poter sviluppare strategie in grado di modularne l'attività'. Questo modulo della commessa prevede una serie di attività volte alla caratterizzazione strutturale di biomolecole complesse mediante tecniche spettroscopiche e diffrattometriche. In questo settore, l'Istituto di Biostrutture e Bioimmagini vanta una lunga tradizione ed attrezzature d'avanguardia. Indagini strutturali mediante tecniche sperimentali avranno un ruolo fondamentale per il raggiungimento dei seguenti obiettivi della commessa (a) caratterizzazione di target per antibiotici, (b) studio di sistemi macromolecolari implicati in patologie del sistema nervoso, (c) sviluppo di anticorpi e caratterizzazione di proteine coinvolte nei processi di coagulazione (d) sviluppo di nuovi inibitori di anidrasi carboniche per applicazioni diagnostiche e farmaceutiche, e (e) studio di enzimi e proteine globulari e fibrose di interesse biotecnologico. (literal)

Nome

• Determinazione della struttura tridimensionale di biomolecole complesse con tecniche spettroscopiche e cristallografiche (literal)

Descrizione

• Descrizione collaborazioni del modulo "Determinazione della struttura tridimensionale di biomolecole complesse con tecniche spettroscopiche e cristallografiche (PM.P01.022.001)" (Descrizione collaborazioni)
• Descrizione del modulo "Determinazione della struttura tridimensionale di biomolecole complesse con tecniche spettroscopiche e cristallografiche (PM.P01.022.001)" (Descrizione modulo)
• Descrizione dello stato di avanzamento delle attività del modulo "Determinazione della struttura tridimensionale di biomolecole complesse con tecniche spettroscopiche e cristallografiche (PM.P01.022.001)" (Descrizione stato avanzamento attività)

Modulo di

• Caratterizzazione strutturale di molecole complesse di interesse biomedico o biotecnologico (PM.P01.022) (Commessa)

Gestore

• GIUSEPPINA DE SIMONE (Persona)

Incoming links:

Prodotto di

• STRUCTURAL ANALYSIS OF THE TRANSCRIPTIONAL REGULATOR BALD16 FROM SULFOLOBUS SOLFATARICUS (Contributo in atti di convegno) (Prodotto della ricerca)
• Accurate computation of fluorescence spectra in solution: A time-dependent DFT study on the excited states of some uracil derivatives in water and acetonitrile solution (Contributo in atti di convegno) (Prodotto della ricerca)
• Electron Transfer To Flat Peptides (Contributo in atti di convegno) (Prodotto della ricerca)
• Conformational Study of Self-Asembling Peptides (Contributo in atti di convegno) (Prodotto della ricerca)
• CARBONIC ANHYDRASE INHIBITORS: X-RAY AND MOLECULAR MODELING STUDY FOR THE INTERACTION OF A FLUORESCENT ANTITUMOR SULFONAMIDE WITH ISOZYME II AND IX (Contributo in atti di convegno) (Prodotto della ricerca)
• A molecular dynamics study of pilin subunits: insights into pilus biogenesis (Contributo in atti di convegno) (Prodotto della ricerca)
• Raman-assisted Biocrystallography. Applications to metal proteins (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Monitoring the prepration of protein derivative crystals via Raman-microscopy (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• A CUL3-DERIVED PEPTIDE BINDING DIFFERENT MEMBERS OF THE KCTD FAMILY (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• PRELIMINARY CHARACTERIZATION OF BRUCELLA SUIS HYSTIDINOL DEHYDROGENASE (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Structural and functional characterization of the Cul3 adaptor RENKCTD11 (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Structural and functional characterisation of hemoglobins of Eleginops maclovinus, a sub-Antarctic notothenioid fish Proteine (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Linkage between Root effect and hemichrome stability (Contributo in atti di convegno) (Prodotto della ricerca)
• Physico-chemical effects influencing the rate of the dissociative electron transfer in polypeptide systems. (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• CARBONIC ANHYDRASE INHIBITORS: HYPOXIA-ACTIVATABLE SULFONAMIDES INCORPORATING DISULFIDE BONDS THAT TARGET THE TUMOR-ASSOCIATED ISOFORM I (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• 3D Structural Characterization of a Thermostable Thioredoxin Reductase Isolated from Sulfolobus solfataricus (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Stereochemistry, formation and reactivity of hemichromes in Antarctic fish hemoglobins (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• A novel method for detection of Se-Met inclusion into protein crystals via Raman microscopy (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Structural and functional characterization of Resuscitatin-Promoting Factors from Mycobacterium tuberculosis (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Dormancy in Mycobacterium tuberculosis: the role of resuscitation-promoting factors (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Raman-assisted biocrystallography” Gordon Conference: Vibrational Spectroscpy (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Raman-assisted biocrystallography of metal-proteins (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• THE CRYSTAL STRUCTURE OF HCA I/TOPIRAMATE COMPLEX PROVIDES USEFUL INSIGHTS INTO RATIONAL DRUG DESIGN OF ANTI-OBESITY DRUGS (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Crystal structure of the ribosome inactivating protein PD-L3 from Phytolacca dioica (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• bases of M. tuberculosis daughter cell separation (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• STRUCTURAL AND FUNCTIONAL INSIGHTS INTO BCP4: COMPONENT OF THE ANTIOXIDANT SYSTEM OF SULFOLOBUS SOLFATARICUS (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• KCTD7: a new substrate-specific adaptor for Cul3 involved in Progressive Myoclonic Epilepsy (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Open interface and large quaternary structure movements in 3D domain swapped proteins: insights from molecular dynamics simulations of the C-terminal swapped dimer of ribonuclease A (Articolo in rivista) (Prodotto della ricerca)
• A crevice adjoining the ribosome tunnel: Hints for cotranslational folding. (Articolo in rivista) (Prodotto della ricerca)
• Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies. (Articolo in rivista) (Prodotto della ricerca)
• Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Very late onset in ataxia oculomotor apraxia type I. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbonic anhydrase inhibitors: hypoxia-activatable sulfonamides incorporating disulfide bonds that target the tumor-associated isoform IX (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The first crystal structure of a thioacylenzyme intermediate in the ALDH family: New coenzyme conformation and relevance to catalysis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A Parameter Free Quantum Mechanical Approach to the Calculation of Electron Transfer Rates for Large Systems in Solution (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Dissociative Electron Transfer in Donor-Peptide-Acceptor Systems: Results for Kinetic Parameters from a Density Functional/Polarizable Continuum Model (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 2-Substituted Estradiol Bis-sulfamates, Multitargeted Antitumor Agents: Synthesis, In Vitro SAR, Protein Crystallography, and In Vivo Activity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (Articolo in rivista) (Prodotto della ricerca)
• Atomic resolution (1.1 A) structure the of Ribosome-Inactivating Protein PD-L4 from Phytolacca dioica L. leaves (Articolo in rivista) (Prodotto della ricerca)
• Correlation between Raman and X-ray crystallography data of (Pro-Pro-Gly)10 (Articolo in rivista) (Prodotto della ricerca)
• Spectroscopic and crystallographic characterization of hemichromes in tetrameric hemoglobins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A novel method for detection of Se-Met inclusion into protein crystals via Raman microscopy (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Role of side chains in collagen triple helix stabilization and partner recognition (Articolo in rivista) (Prodotto della ricerca)
• Recent advances in structural studies of the carbonic anhydrase family: the crystal structure of human CA IX and CA XIII. (Articolo in rivista) (Prodotto della ricerca)
• Carbonic anhydrase IX: Biochemical and crystallographic characterization of a novel antitumor target. (Articolo in rivista) (Prodotto della ricerca)
• Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation (Articolo in rivista) (Prodotto della ricerca)
• Crystallization and preliminary x-ray crystallographic analysis of Sulfolobus solfataricus thioredoxin reductase (Articolo in rivista) (Prodotto della ricerca)
• nteractions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor. (Articolo in rivista) (Prodotto della ricerca)
• Unraveling the structural and functional features of an aldolase A mutant involved in the hemolytic anemia and severe rhabdomyolysis reported in a child (Articolo in rivista) (Prodotto della ricerca)
• he role of the hinge loop in domain-swapping: The special case of Bovine seminal Ribonuclease. (Articolo in rivista) (Prodotto della ricerca)
• Lessons from crystals grown in the Advanced Protein Crystallisation Facility for conventional crystallisation applied to structural biology. (Articolo in rivista) (Prodotto della ricerca)
• Molecular dynamics analyses of cross-b-spine steric zipper models: b-sheet twisting and aggregation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbonic Anhydrase Inhibitors: X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Chemical denaturation of the elongation factor 1a isolated from the hyperthermophilic archaeon Sulfolobus solfataricus (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Polyglutamine repeats and beta-helix structure: Molecular dynamics study (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 23S rRNA 2058A-->G alteration mediates ketolide resistance in combination with deletion in L22 (Articolo in rivista) (Prodotto della ricerca)
• A Novel Type of Zinc Finger DNA Binding Domain in the Agrobacterium tumefaciens Transcriptional Regulator Ros (Articolo in rivista) (Prodotto della ricerca)
• Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides - Solution and crystallographic studies (Articolo in rivista) (Prodotto della ricerca)
• Antiobesity carbonic anhydrase inhibitors (Articolo in rivista) (Prodotto della ricerca)
• Crystallization and preliminary X-ray diffraction analysis of PD-L1, a highly glycosylated ribosome inactivating protein with DNase activity (Articolo in rivista) (Prodotto della ricerca)
• Functional And Structural Charateristics Of The Oxyanion Hole In A Thermophilic Esterase From Alyciclobacillus Acidocaldarius (Articolo in rivista) (Prodotto della ricerca)
• Atomic resolution (1.1 A) structure of the ribosome-inactivating protein PD-L4 from Phytolacca dioica L. leaves. (Articolo in rivista) (Prodotto della ricerca)
• Crystallization and preliminary X-ray diffraction studies of a psychrophilic iron superoxide dismutase from Pseudoalteromonas haloplanktis (Articolo in rivista) (Prodotto della ricerca)
• Anticancer steroid sulfatase inhibitors: Synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography. (Articolo in rivista) (Prodotto della ricerca)
• Investigations of the esterase, phosphatase, and sulfatase activities of the cytosolic mammalian carbonic anhydrase isoforms I, II, and XIII with 4-nitrophenyl esters as substrates (Articolo in rivista) (Prodotto della ricerca)
• Carbonic anhydrase inhibitors: binding of indanesulfonamides to the human isoform II (Articolo in rivista) (Prodotto della ricerca)
• Dynamics and stability of amyloid-like steric zipper assemblies with hydrophobic dry interfaces. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Inhibition of the R1 fragment of the cadmium-containing zeta-class carbonic anhydrase from the diatom Thalassiosira weissflogii with anions. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Multiple catalytically active thioredoxin folds: a winning strategy for many functions. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Drug design studies of the novel antitumor targets carbonic anhydrase IX and XII (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structure and flexibility in cold-adapted iron superoxide dismutases: the case of the enzyme isolated from Pseudoalteromonas haloplanktis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Minimal structural requirements for root effect: Crystal structure of the cathodic hemoglobin isolated from the antarctic fish Trematomus newnesi. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A contribution to the solvation free energy in isotropic and anisotropic polarizable continuum model. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Crystallization and preliminary X-ray crystallographic analysis of the Sulfolobus solfataricus nucleotide-exchange factor 1b (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Correlation between Omega and Psi Dihedral Angles in Protein Structures (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Insight into Ribonuclease A Domain Swapping by Molecular Dynamics Unfolding Simulations (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The importance of dynamic effects on the enzyme activity: X-ray structure and molecular dynamics of onconase. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structural characterization of the oxidation pathway of antarctic fish hemoglobins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II \"selective\" inhibitor celecoxib. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Polyproline helices in protein structures: a statistical survey (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• CARBONIC ANHYDRASE INHIBITORS: X-RAY CRYSTALLOGRAPHIC STUDIES FOR THE BINDING OF 5-AMINO-1,3,4-THIADIZOLE-2-SULFONAMIDE AND 5-(4-AMINO-3-CHLORO-5-FLUOROPHENYLSULFONAMIDO)-1,3,4-THIADIAZOLE-2-SULFONAMIDE TO HUMAN ISOFORM II (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Approximate values for force constant and wave number associated with a low-frequency concerted motion in proteins can be evaluated by a comparison of X-ray structures (Articolo in rivista) (Prodotto della ricerca)
• Carbonic anhydrase inhibitors: binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties (Articolo in rivista) (Prodotto della ricerca)
• A novel method for detection of Se-Met inclusion into protein crystals via Raman microscopy (Articolo in rivista) (Prodotto della ricerca)
• Five human phenylalanine hydroxylase proteins identified in mild hyperphenylalaninemia patients are disease-causing variants (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• In HspA from Helicobacter pylori vicinal disulfide bridges are a key determinant of domain B structure (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Conformational states and association mechanism of Yersinia pestis Caf1 subunits. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of Thr200 and Gln92 for obtaining tight-binding inhibitors. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Recent Advances in Research on the Most Novel Carbonic Anhydrases, CA XIII and XV (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Molecular dynamics studies of the P pilus rod subunit PapA (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Ribosome's mode of function: myths, facts and recent results (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Biochemical characterisation of the D60A mutant of the elongation factor 1 from the archaeon Sulfolobus solfataricus (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Comment on Microfibrillar structure of type I collagen in situ by Orgel et al. (2006), Proc. Natl Acad. Sci. USA, 103, 9001-9005 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Exploring the catalytic mechanism of the first dimeric Bcp: Functional, structural and docking analyses of Bcp4 from Sulfolobus solfataricus. (Articolo in rivista) (Prodotto della ricerca)
• The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex. (Articolo in rivista) (Prodotto della ricerca)
• Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis (Articolo in rivista) (Prodotto della ricerca)
• Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the peptidoglycan binding region of the Ser/Thr kinase PrkC from Staphylococcus aureus (Articolo in rivista) (Prodotto della ricerca)
• Crystallization and Preliminary X-Ray Crystallographic Analysis of the Complex of Human Alpha Thrombin With A Modified Thrombin Binding Aptamer (Articolo in rivista) (Prodotto della ricerca)
• A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish (Articolo in rivista) (Prodotto della ricerca)
• HE CRYSTAL STRUCTURE OF A FERULOYL ESTERASE FROM THE PSYCHROPHILIC BACTERIUM PSEUDOALTEROMONAS HALOPLANKTIS TAC125 (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• CRYSTAL STRUCTURE OF A PROTEIN DISULFIDE OXIDOREDUCTASE FROM AEROPYRUM PERNIX K1 (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• DEVELOPMENTS IN THE DESIGN OF ANTITUMOR CARBONIC ANHYDRASE INHIBITORS (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Structural characterization of a thermostable thioredoxin reductase isolated from Sulfolobus solfataricus (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• 3D Structure of Archaeal Elongation Factors by Synchrotron Radiation (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• A combined Raman microscopy and X-ray crystallography approach to study protein single crystals (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• STRUCTURAL CHARACTERIZATION OF HUMAN CARBONIC ANHYDRASE (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• STRUCTURAL CHARACTERIZATION OF CARBONIC ANHYDRASE INHIBITORS INCORPORATING NEW METAL BINDING FUNCTIONALITIES (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• resolution X-ray structure of the complex of human alpha thrombin with a modified thrombin binding aptamer (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Crystallographic studied of ribosome inactivating proteins (Comunicazione a convegno) (Prodotto della ricerca)
• Revival of M. tuberculosis from latency. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• The hemoglobins of fishes living at polar latitudes- Current knowledge on structural adaptations in a challenging environment (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Insights into the catalytic mechanism of the carbonic anhydrase family from the crystal structure of human isoform (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Evidence for an elongated dimeric structure of heparin-binding haemaglutinin from M. tuberculosis (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Exploring the antioxidant system of Sulfolobus solfataricus: structural and functional analysis of peroxiredoxin Bcp1 (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Carbonic Anhydrase inhibitors: bioreductive nitro-containing sulfonamides targeting the tumor-associated isoforms CA IX and XII (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Understanding the Structural Bases of Collagen Triple Helix Stability (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Bis-Histidyl adducts in tetrameric hemoglobins (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• ADVANCES IN THE INHIBITORY AND STRUCTURAL INVESTIGATIONS ON CARBONIC ANHYDRASE ISOZYMES XIII AND XV In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• DRUG DESIGN OF ANTIOBESITY CARBONIC ANHYDRASE INHIBITORS. In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Insight into old and new questions in structural biology by experimental and computational methodologies (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Host-pathogen adhesion at an atomic level. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Root effect also functions modulating the hemichrome stability in tetrameric hemoglobins (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Insights Into The Catalytic Mechanism Of The Bcp Family: Functional And Structural Analysis Of Bcp1 From Sulfolobus Sulfataricus (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• combined femtosecond fluorescence and TD-DFT study of uracil derivatives in aqueous solution Femtochemistry VII Fundamental Ultrafast Processes (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• -RAY CRYSTALLOGRAPHY OF CARBONIC ANHYDRASE INHIBITORS AND ITS IMPORTANCE IN DRUG DESIGN. In Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Towards the understanding the structural bases of collagen triple helix stability (Monografia o trattato scientifico) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1401)
• Insights on a new PDI-like family: structural and functional analysis of a protein disulfide oxidoreductase from the bacterium Aquifex aeolicus. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Heterodimeric peptide compounds displaying NGF activity and their use to treat neurodegenerative disorders (Brevetto) (Brevetto)
• High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: the role of histidine residues in modulating the strength of the root effect (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Biophysical and biochemical characterization of a liposarcoma-derived recombinant MnSOD protein acting as an anticancer agent (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Minimal structural requirements for Root effect: Crystal structure of the cathodic hemoglobin isolated from the antarctic fish Trematomus newnesi (Articolo in rivista) (Prodotto della ricerca)
• Crystallization and preliminary x-ray diffraction studies of a protein disulfide oxidoreductase from Aeropyrum pernix K1 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Crystallization, preliminary X-ray diffraction studies and Raman microscopy of the major hemoglobin from the sub-Antarctic fish Eleginops maclovinus in the carbomonoxy form. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Femtosecond study on the isomerization dynamics of NK88: I. Ground state dynamics after photoexcitation (Articolo in rivista) (Prodotto della ricerca)
• The Root effect - a structural and evolutionary perspective. (Articolo in rivista) (Prodotto della ricerca)
• Reduction of ferric hemoglobin from Trematomus bernacchii in a partial bis-histidyl state produces a deoxy coordination even when encapsulated into the crystal phase (Articolo in rivista) (Prodotto della ricerca)
• Biochemical characterization of CA IX, one of the most active Carbonic Anhydrase isozymes. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structural characterization of ferric hemoglobins from three Antarctic fish species of the suborder Notothenioidei (Articolo in rivista) (Prodotto della ricerca)
• Functional and structural features of the oxyanion hole in a thermophilic esterase from Alicyclobacillus acidocaldarius (Articolo in rivista) (Prodotto della ricerca)
• A novel member of the protein disulfide oxidoreductase family from Aeropyrum pernix K1: structure, function and electrostatics. (Articolo in rivista) (Prodotto della ricerca)
• An order-disorder transition plays a role in switching off the Root effect in fish hemoglobins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The crystal structure of the superoxide dismutase from Helicobacter pylori reveals a structured C-terminal extension (Articolo in rivista) (Prodotto della ricerca)
• Structural determinats of M. tuberculosis agglutination guided by heparin binding hemagglutinin (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Heterotypic Sam-Sam association between Odin-Sam1 and Arap3-Sam: binding affinity and structural insights. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Solution structure of the first Sam domain of Odin and binding studies with the EphA2 receptor. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structure and dimerization of the teleost transmembrane immunoglobulin region (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Crystal structure of an S-formylglutathione hydrolase from pseudoalteromonas haloplanktis TAC125. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Identification and characterization of a new form of oncosuppressor KCTD11 (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Carbonic anhydrase inhibitors: bioreductive nitro-containing sulfonamides with selectivity for targeting the tumor associated isoforms IX and XII. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II. (Articolo in rivista) (Prodotto della ricerca)
• Design and NMR studies of cyclic peptides targeting the N-terminal domain of the protein tyrosine phosphatase YopH. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Crystallization and preliminary X-ray crystallographic analysis of ligand-free and arginine-bound forms of Thermotoga maritima arginine-binding protein (Articolo in rivista) (Prodotto della ricerca)
• A new RNasesheds light on the RNase/angiogenin subfamily from zebrafish (Articolo in rivista) (Prodotto della ricerca)
• (In)organic anions as carbonic anhydrase inhibitors (Articolo in rivista) (Prodotto della ricerca)
• Carbonic anhydraseinhibitors: X-ray crystallographic studies for the binding of N-substitutedbenzenesulfonamides to human isoform II (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candidaalbicans and Candida glabrata (Articolo in rivista) (Prodotto della ricerca)
• Thrombin-aptamer recognition: a revealed ambiguity (Articolo in rivista) (Prodotto della ricerca)
• Occurrence and formation of endogenous histidine hexa-coordination incold-adapted hemoglobins. IUBMB Life (Articolo in rivista) (Prodotto della ricerca)
• Protonation of histidine 55 affects the oxygen access to heme in the alpha chain of the hemoglobin from the Antarctic fish Trematomus bernacchii (Articolo in rivista) (Prodotto della ricerca)
• Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Expression,purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacteriumtuberculosis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Improving Protein Crystal Quality by the Without-Oil Microbatch Method: Crystallization and Preliminary X-ray Diffraction Analysis of Glutathione Synthetase from Pseudoalteromonas haloplanktis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Gene cloning andprotein expression of ?-glutamyltranspeptidases from Thermus thermophilus and Deinococcus radiodurans: comparison of molecular and structural properties withmesophilic counterparts (Articolo in rivista) (Prodotto della ricerca)
• A novel ErbB2 epitope targeted by humanantitumor immunoagents (Articolo in rivista) (Prodotto della ricerca)
• CD and NMR conformational studies of a peptide encompassing the Mid Loop interface of Ship2-Sam (Articolo in rivista) (Prodotto della ricerca)
• Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish (Articolo in rivista) (Prodotto della ricerca)
• Structural insights into and activity analysis of the antimicrobial peptide myxinidin (Articolo in rivista) (Prodotto della ricerca)
• Hydrophobic Substituents of the Phenylmethylsulfamide Moiety Can Be Used for the Development of New Selective Carbonic Anhydrase Inhibitors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• G-quadruplex DNA recognition by nucleophosmin: New insights from protein dissection (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 3D domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Peptides targeting chemokine receptor CXCR4: Structural behavior and biological binding studies (Articolo in rivista) (Prodotto della ricerca)
• Multiple binding modes of inhibitors to carbonic anhydrases: How to design specific drugs targeting 15 different isoforms? (Articolo in rivista) (Prodotto della ricerca)
• Hydroxamate represents a versatile zinc binding group for the development of new carbonic anhydrase inhibitors (Articolo in rivista) (Prodotto della ricerca)

Modulo

• Caratterizzazione strutturale di molecole complesse di interesse biomedico o biotecnologico (PM.P01.022) (Commessa)

Gestore di

• GIUSEPPINA DE SIMONE (Persona)

Istituto esecutore di

• Institute of biostructure and bioimaging (IBB) (Istituto)

Descrizione di

• Descrizione del modulo "Determinazione della struttura tridimensionale di biomolecole complesse con tecniche spettroscopiche e cristallografiche (PM.P01.022.001)" (Descrizione modulo)
• Descrizione dello stato di avanzamento delle attività del modulo "Determinazione della struttura tridimensionale di biomolecole complesse con tecniche spettroscopiche e cristallografiche (PM.P01.022.001)" (Descrizione stato avanzamento attività)
• Descrizione collaborazioni del modulo "Determinazione della struttura tridimensionale di biomolecole complesse con tecniche spettroscopiche e cristallografiche (PM.P01.022.001)" (Descrizione collaborazioni)