Neurobiologia e Neuropatologia (ME.P02.005.001)

Type

• Modulo (Classe)

Label

• Neurobiologia e Neuropatologia (ME.P02.005.001) (literal)

Prodotto

• Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Double anchorage to the membrane and intact inter-chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Translocation of signalling proteins to the plasma membrane revealed by a new bioluminescent procedure (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Activation of the mitochondrial permeability transition pore modulates Ca2+ responses to physiological stimuli in adult neurons (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Time course and temperature dependence of the membrane translocation of tetanus and botulinum neurotoxins C and D in neurons (Articolo in rivista) (Prodotto della ricerca)
• Tetanus neurotoxin (Articolo in rivista) (Prodotto della ricerca)
• Pyrvinium pamoate does not activate protein kinase CK1, but promotes Akt/PKB down-regulation and GSK3 activation (Articolo in rivista) (Prodotto della ricerca)
• Quercetin mitochondriotropic derivatives antagonize nitrate tolerance and endothelial dysfunction of isolated rat aorta rings (Articolo in rivista) (Prodotto della ricerca)
• The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase (Articolo in rivista) (Prodotto della ricerca)
• Neurotoxicity of European viperids in Italy: Pavia Poison Control Centre case series 2001-2011 (Articolo in rivista) (Prodotto della ricerca)
• Botulinum neurotoxin type A is internalized and translocated from small synaptic vesicles at the neuromuscular junction (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Why myotoxin-containing snake venoms possess powerful nucleotidases? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca2+-activated K+ channel mtKCa3.1. (Articolo in rivista) (Prodotto della ricerca)
• Botulinum neurotoxin serotype D is poorly effective in humans: An in vivo electrophysiological study (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• NIM811, a cyclophilin inhibitor without immunosuppressive activity, is beneficial in collagen VI congenital muscular dystrophy models (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial dysfunction in the pathogenesis of Ullrich congenital muscular dystrophy and prospective therapy with cyclosporins. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Induction of the permeability transition pore in cells depleted of mitochondrial DNA (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The permeability transition pore as a Ca2+ release channel: New answers to an old question (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Monoamine oxidase inhibition prevents mitochondrial dysfunction and apoptosis in myoblasts from patients with collagen VI myopathies (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effects of the CK2 Inhibitors CX-4945 and CX-5011 on Drug-Resistant Cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Emerging Protein Targets for Anticancer Metallodrugs: Inhibition of Thioredoxin Reductase and Cathepsin B by Antitumor Ruthenium (II)-Arene Compounds. (Articolo in rivista) (Prodotto della ricerca)
• Src-Tyrosine kinases are major agents in mitochondrial tyrosine phosphorylation. (Articolo in rivista) (Prodotto della ricerca)
• Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels. (Articolo in rivista) (Prodotto della ricerca)
• Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect fuctional links with cystic fibrosis pathogenesis. (Articolo in rivista) (Prodotto della ricerca)
• Mass spectrometry analysis of a protein kinase CK2beta subunit interactome isolated from mouse brain by affinity chromatography. (Articolo in rivista) (Prodotto della ricerca)
• Ca2+ oscillation frequency decoding in cardiac cell hypertrophy: role of calcineurin/NFAT as Ca2+ signal integrators. (Articolo in rivista) (Prodotto della ricerca)
• Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage. (Articolo in rivista) (Prodotto della ricerca)
• A mitochondriotropic derivative of quercetin: a strategy to increase the effectiveness of polyphenols. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Development of mitochondrial-targeted derivatives o resveratrol. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The role of autophagy in neonatal tissues: just a response to starvation? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Thiol chemistry in peroxidase catalysis and redox signaling. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Gold(I) complexes determine apoptosis with limited oxidative stress in Jurkat T cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Correlation between fluidising effects on phospholipid membranes and mitochondrial respiration of propofol and p-nitrosophenol homologues. (Articolo in rivista) (Prodotto della ricerca)
• Altered threshold of the mitochondrial permeability transition pore in Ullrich congenital muscular dystrophy. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• High glucose induces adipogenic differentiation of muscle-derived stem cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cardiac cell hypertrophy in vitro: role of calcineurin/NFAT as Ca2+ signal integrators. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Stable interactions between mitochondrial and endoplasmic reticulum allow rapid accumulation of calcium in a subpopultatin of mitochondria. (Articolo in rivista) (Prodotto della ricerca)
• Looking forward to seeing calcium. (Articolo in rivista) (Prodotto della ricerca)
• The Theodore Bucher lecture. Investigating signal transduction with genetically encoded fluorescent probes. (Articolo in rivista) (Prodotto della ricerca)
• Binding of N-terminal fragments of anthraz edema factor (EF (N)) and lethal factor (LF (N)) to the protective antigen pore. (Articolo in rivista) (Prodotto della ricerca)
• Eukaryotic translation-initiation factor eIF2beta binds to protein kinase CK2: effects on CK2alpha activity. (Articolo in rivista) (Prodotto della ricerca)
• Altered sensitivity to nociceptive stimuli in mice lacking the CaV2.1ƒalpha1 subunit of P/Q-type Ca2+ channels. (Contributo in atti di convegno) (Prodotto della ricerca)
• Inheruted neuronal ion channelopathies: new windows on complex neurological diseases. (Articolo in rivista) (Prodotto della ricerca)
• Human Keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores. (Articolo in rivista) (Prodotto della ricerca)
• Tyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic actvity. (Articolo in rivista) (Prodotto della ricerca)
• Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Neuromuscular paralysis and recovery in mice injected with botulinum neurotoxins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondria-endoplasmic reticulum choreography: structure and signaling dynamics. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial Ca2+ as a key regulator of cell life and death.. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Direct Detection of Soil-Bound Prions (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Fast spiking interneuron control of seizure propagation in a cortical slice model of focal epilepsy (Articolo in rivista) (Prodotto della ricerca)
• A rapid and sensitive assay of intercellular coupling by voltage imaging of gap junction networks (Articolo in rivista) (Prodotto della ricerca)
• ATP-dependent intercellular Ca2+ signaling in the developing cochlea: Facts, fantasies and perspectives (Articolo in rivista) (Prodotto della ricerca)
• Gold(III)-dithiocarbamato complexes induce cancer cell death triggered by (Articolo in rivista) (Prodotto della ricerca)
• The crystal structure of CagS from the Helicobacter pylori pathogenicity island. (Articolo in rivista) (Prodotto della ricerca)
• Peculiar binding of botulinum neurotoxins. (Articolo in rivista) (Prodotto della ricerca)
• Altered pain sensitivity in mice lacking the CaV2.1alpha1 subunit of P/Q-type Ca2+ channels (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Pain-related behaviours in mice lacking the CaV2.1alpha1 subunit of PQ-type Ca2+ channels (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Properties of Ca2+ Transport in Mitochondria of Drosophila melanogaster (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Redox regulation of T-cell turnover by the p13 protein of human T-cell leukemia virus type 1: distinct effects in primary versus transformed cells. (Articolo in rivista) (Prodotto della ricerca)
• ATP-sensitive cation channel in wheat (Triticum durum Desf.): identification and characterization of a plant mitochondrial channel by patch-clamp. (Articolo in rivista) (Prodotto della ricerca)
• Regioselective O-derivatization of quercetin via ester intermediates. An improved synthesis of rhamnetin and development of a new mitochondriotropic derivative. (Articolo in rivista) (Prodotto della ricerca)
• Role of Kv1.3 mitochondrial potassium channel in apoptotic signalling in lymphocytes. (Articolo in rivista) (Prodotto della ricerca)
• Impact of mitochondriotropic quercetin derivatives on mitochondria. (Articolo in rivista) (Prodotto della ricerca)
• Ca2+ hot spots on the mitochondrial surface are generated by Ca2+ mobilization from stores, but not by activation of store operated Ca2+ channels. (Articolo in rivista) (Prodotto della ricerca)
• Unique characteristics of Ca2+ homeostasis of the trans-Golgi compartment. (Articolo in rivista) (Prodotto della ricerca)
• Golgi apparatus casein kinase phosphorylates bioactive Ser-6 of bone morphogenetic protein 15 and growth and differentiation factor 9. (Articolo in rivista) (Prodotto della ricerca)
• Prion and TNF(alpha): TAC(E)it agreement between the prion protein and cell signaling. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondria: The calcium connection. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial Ca2+ transport and permeability transition in zebrafish (Danio rerio) (Articolo in rivista) (Prodotto della ricerca)
• Functional and structural alterations in the endoplasmic reticulum and mitochondria during apoptosis triggered by C-2-ceramide and CD95/APO-1/FAS receptor stimulation. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition. (Articolo in rivista) (Prodotto della ricerca)
• Myosin Va cooperates with PKA RIa to mediate maintenance of the endplate in vivo. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity and thioredoxin reductase inhibition of a series of gold(I) complexes containing hydrophilic phosphine ligands (Articolo in rivista) (Prodotto della ricerca)
• Addiction to protein kinase CK2: a common denominator of diverse cancer cells? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Thiol redox systems and protein kinases in hepatic stellate cell regulatory processes. (Articolo in rivista) (Prodotto della ricerca)
• Cellular prion protein promotes regeneration of adult muscle tissue. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The mitochondrial permeability transition from yeast to mammals. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cyclophilin D in mitochondrial pathophysiology. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial thioredoxin reductase: purification, inhibitor studies, and role in cell signaling. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Bothrop snake myotoxins induce a large efflux of ATP and potassium with spreading of cell damage and pain. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Imaging the cell entry of the anthrax oedema and lethal toxins with fluorescent protein chimeras. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A new experimental model of focal seizures in the entorhinal cortex (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial matrix pH controls oxidative phosphorylation and metabolism-secretion coupling in INS-1E clonal beta cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• beta(2)-Adrenoceptors, NADPH oxidase, ROS and p38 MAPK: another 'radical' road to heart failure? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Lysophospholipids are evolutionary ancient venom components. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1.3, as a new and selective therapeutic strategy in chronic lymphocytic leukemia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Retinal pigment epithelium (RPE) exosomes contain signaling phosphoproteins affected by oxidative stress (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Dimers of mitochondrial ATP synthase form the permeability transition pore (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Apoptosis to necrosis switching downstream of apoptosome formation requires inhibition of both glycolysis and oxidative phosphorylation in a BCL-X-L- and PKB/AKT-independent fashion (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Kinase CK2 inhibition: An update (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Exploiting the repertoire of CK2 inhibitors to target DYRK and PIM kinases (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Secreted protein kinases? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• CFTR mutations altering CFTR fragmentation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pathophysiology of migraine (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Propagation of chaos and commotion in the wake of cortical spreading depression and spreading depolarizations (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Calcium channels and migraine (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Intracellular ion channels and cancer (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Acetal derivatives as prodrugs of resveratrol (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mass spectrometry analysis of the phospholipase A(2) activity of snake pre-synaptic neurotoxins in cultured neurons. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain (Articolo in rivista) (Prodotto della ricerca)
• Evidence for a radial snare super-complex mediating neurotransmitter release at the drosophila neuromuscular junction (Articolo in rivista) (Prodotto della ricerca)
• Neurotoxicity of inverted-cone shaped lipids (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Measurements of mitochondrial calcium in vivo. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The thioredoxin reductase-thioredoxin system is involved in the entry of tetanus and botulinum neurotoxins in the cytosol of nerve terminals (Articolo in rivista) (Prodotto della ricerca)
• CK1delta Kinase Activity Is Modulated by Chk1-Mediated Phosphorylation (Articolo in rivista) (Prodotto della ricerca)
• Odorant receptors at the growth cone are coupled to localized cAMP and Ca2+ increases (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Modulation of mitochondrial K+ permeability and reactive oxygen species production by the p13 protein of human T-cell leukemia virus type 1. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• From cell protection to death: may Ca2+ signals explain the chameleonic attributes of the mammalian prion protein? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cyclophilin D modulates mitochondrial F0F1-ATP aynthase by interacting with the lateral stalk of the complex. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Novel channels of the inner mitochondrial membrane (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Treatment of human cancer cells with selenite or tellurite in combination with auranofin enhances (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Intermediate conductance Ca2+-activated potassium channel (KCa3.1) in the inner mitochondrial membrane of human colon cancer cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cyclosporin A corrects mitochondrial dysfunction and muscle apoptosis in patients with collagen VI myopathies. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial Ca2+ Uptake Induces Cyclic AMP Generation in the Matrix and Modulates Organelle ATP Levels (Articolo in rivista) (Prodotto della ricerca)
• Quercetin can act either as an inhibitor or an inducer of the Mitochondrial Permeability Transition Pore: a demonstration of the ambivalent redox character of polyphenols (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Soluble polyphenols: synthesis and bioavailability of 3,4',5-tri(alpha-D-glucose-3-O-succinyl)resveratrol. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pathophysiology of mitochondrial volume homeostasis: Potassium transport and permeability transition. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Respiratory Complex I Dysfunction Due to Mitochondrial DNA Mutations Shifts the Voltage Threshold for Opening of the Permeability Transition Pore toward Resting Levels. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A CaPful of mechanisms regulating the mitochondrial permeability transition (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Different mechanisms of inhibition of nerve terminals by botulinum and snake presynaptic neurotoxins. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• High cortical spreading depression susceptibility and migraine-associated symptoms in Ca(v)2.1 S218L mice. (Articolo in rivista) (Prodotto della ricerca)
• The 3.5 angstrom X-ray structure of the human connexin26 gap junction channel is unlikely that of a fully open channel (Articolo in rivista) (Prodotto della ricerca)
• Red wine and green tea reduce H pylori- or VacA-induced gastritis in a mouse model (Articolo in rivista) (Prodotto della ricerca)
• Behavioural effects due to injection of botulinum neurotoxins in central nervous system (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Central injection of botulinum neurotoxins: toxicology and behavioural effects in mice (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Altered sensitivity to nociception stimuli in mice lacking the CaV2.1alpha1 subunit of PQ-type Ca2+ channels (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• pH dependence of human CaV2.1 channels and its alteration by a familial hemiplegic migraine mutation (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• pH dependence of human CaV2.1 channels and its alteration by a familial hemiplegic migraine mutation (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• PH dependence of human CaV2.1 channels and its alteration by a familial hemiplegic migraine mutation. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Central injection of botulinum neurotoxins: toxicology, brain localization and bahavioural effects in mice (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Toxicological and behavioural effects of botulinum neurotoxins injected in central nervous system (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• The lysine-specific demethylase 1 is a novel substrate of protein kinase CK2 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mechanism underlying unaltered cortical inhibitory synaptic transmission in contrast with enhanced excitatory transmission in Ca(V)2.1 knockin migraine mice (Articolo in rivista) (Prodotto della ricerca)
• Synthesis and Properties of a Selective Inhibitor of Homeodomain-Interacting Protein Kinase 2 (HIPK2) (Articolo in rivista) (Prodotto della ricerca)
• Identification of the PLK2-Dependent Phosphopeptidome by Quantitative Proteomics (Articolo in rivista) (Prodotto della ricerca)
• CK2 involvement in ESCRT-III complex phosphorylation (Articolo in rivista) (Prodotto della ricerca)
• Molecular dynamics simulations highlight structural and functional alterations in deafness-related M34T mutation of connexin 26 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects in Col6a1(-/-) myopathic mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Phosphorylation and activation of the atypical kinase P53-related protein kinase (PRPK) by Akt/PKB. (Articolo in rivista) (Prodotto della ricerca)
• Calcium dynamics in the peroxisomal lumen of living cells. (Articolo in rivista) (Prodotto della ricerca)
• A maxi chloride channel in the inner membrane of mammalian mitochondria. (Articolo in rivista) (Prodotto della ricerca)
• Cross-talk between PDGF and S1P signalling elucidates the inhibitory effect and potential antifibrotic action of the immunomodulator FTY720 in activated HSC-cultures. (Articolo in rivista) (Prodotto della ricerca)
• The regulatory beta subunit of protein kinase CK2 contributes to the recognition of the substrate consensus sequence. A study with an eIF2 beta-derived peptide. (Articolo in rivista) (Prodotto della ricerca)
• The selectivity of inhibitors of protein kinase CK2: an uptade. (Articolo in rivista) (Prodotto della ricerca)
• Snake PLA2 neurotoxins enter neurons, bind specifically to mitochondria and open their transition pores. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Comparative analysis of CK2 expression and function in tumor cell lines displaying sensitivity vs. resistance to chemical induced apoptosis. (Articolo in rivista) (Prodotto della ricerca)
• Actin reorganization is abnormal and cellular ATP is decreased in Hailey-Hayley keratinocytes. (Articolo in rivista) (Prodotto della ricerca)
• One-thousand-and-one substrates of protein kinase CK2? (Articolo in rivista) (Prodotto della ricerca)
• Plant polyphenols inhibit VacA, toxin secreted by the gastic pathogen Helecobacter pylory. (Articolo in rivista) (Prodotto della ricerca)
• Traffic of botulinum toxins A and E in excitatory and inhibitory neurons. (Articolo in rivista) (Prodotto della ricerca)
• Differential effect of calcium ions on the cytosolic and mitochondrial thioredoxin reductase. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Astrocytic glutamate is not necessary for the generation of epileptiform neuronal activity in hippocampal slices. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Preface to Mitochondria and Cardioprotection (Articolo in rivista) (Prodotto della ricerca)
• Construction and test of a GRIN-based optical objective (Articolo in rivista) (Prodotto della ricerca)
• A glutamine synthetase inhibitor increases survival and decreases cytokine response in a mouse model of acute liver failure (Articolo in rivista) (Prodotto della ricerca)
• Bax does not directly partecipate in the Ca2+ - induced permeability transition of isolated mitochondria (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The modulation of thiol redox state affects the production and metabolism and hydrogen peroxide by heart mitochondrial. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial function and myocardial aging. A critical analysis of the role of permeability transition (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial Ca2+ homeostasis: mechanism, role, and tissue specificities (Articolo in rivista) (Prodotto della ricerca)
• Human doppel and prion protein share common membrane microdomains and internalization pathways. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK-MAPK activation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Inhibition of complex I regulates the mitochondrial permeability transition through a phosphate-sensitive inhibitory site masked by cyclophilin D (Articolo in rivista) (Prodotto della ricerca)
• The Pathophysiology of LETM1 (Articolo in rivista) (Prodotto della ricerca)
• Phosphate is essential for inhibition of the mitochondrial permeability transition pore by cyclosporin A and by cyclophilin D ablation. (Articolo in rivista) (Prodotto della ricerca)
• Migraine: a disorder of brain excitatory-inhibitory balance? (Articolo in rivista) (Prodotto della ricerca)
• Glutamate-mediated astrocyte-to-neuron signalling in the rat dorsal horn. (Articolo in rivista) (Prodotto della ricerca)
• Permeation Pathway of Homomeric Connexin 26 and Connexin 30 Channels Investigated by Molecular Dynamics (Articolo in rivista) (Prodotto della ricerca)
• The contribution of astrocyte signalling to neurovascular coupling. (Articolo in rivista) (Prodotto della ricerca)
• Reduced phosphatidylinositol 4,5-bisphosphate synthesis impairs inner ear Ca2+ signaling and high-frequency hearing acquisition (Articolo in rivista) (Prodotto della ricerca)
• Astrocyte dysfunction in epilepsy. (Articolo in rivista) (Prodotto della ricerca)
• Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2. (Articolo in rivista) (Prodotto della ricerca)
• Signal transduction to the permeability transition pore. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrially targeted anti-cancer agents (Articolo in rivista) (Prodotto della ricerca)
• Contribution of voltage-gated potassium channels to the regulation of apoptosis. (Articolo in rivista) (Prodotto della ricerca)
• Electrophysiology clarifies the megariddles of the mitochondrial permeability transition pore. (Articolo in rivista) (Prodotto della ricerca)
• Altered store operated calcium entry increases cyclic 3',5'-adenosine monophosphate production and extracellular signal-regulated kinases 1 and 2 phosphorylation in polycystin-2-defective cholangiocytes (Articolo in rivista) (Prodotto della ricerca)
• Ca2+ signalling in the Golgi apparatus (Articolo in rivista) (Prodotto della ricerca)
• Copper (II) binding to the human Doppel protein may mark its functional diversità from the prion protein (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• No evidence for inositol 1,4,5-trisphosphate-dependent Ca2+ release in isolated fibers of adult mouse skeletal muscle (Articolo in rivista) (Prodotto della ricerca)
• The anthrax lethal factor and its MAPK kinase-specific metalloprotease activity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Calcium overload in nerve terminals of cultured neurons intoxicated by alpha-latrotoxin and snake PLA2 neurotoxins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Dephosphorylation and inactivation of Akt/PKB is counteracted by protein kinase CK2 in HEK 293T cells. (Articolo in rivista) (Prodotto della ricerca)
• Calcium elevation in mitochondria is the main Ca2+ requirement for mitochondrial permeability transition pore (mPTP) opening. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Is indeed the prion protein an Harlequin servant of “many” masters? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Enhanced excitatory transmission at cortical synapses as the basic for facilitated spreading depression in Ca(v) 2.1 knockin migraine mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Heterogeneity and standardization of Phase II metabolism in cultured cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Absorption and metabolism of resveratrol carboxyesters and methanesulfonate by explanted rat intestinal segments. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Ca 2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2 (Articolo in rivista) (Prodotto della ricerca)
• Fluorescent silver(i) and gold(i)-N-heterocyclic carbene complexes with cytotoxic properties: Mechanistic insights (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Principles in redox signaling: From chemistry to functional significance (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Developmental Shift of Cyclophilin D Contribution to Hypoxic-Ischemic Brain Injury. (Articolo in rivista) (Prodotto della ricerca)
• The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondria and vascular pathology. (Articolo in rivista) (Prodotto della ricerca)
• Calpain activity contributes to the control of SNAP-25 levels in neurons. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Aberrant signalling by protein kinase CK2 in imatinib-resistant chronic myeloid leukaemia cells: Biochemical evidence and therapeutic perspectives (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Phosphorylation of cystic fibrosis transmembrane conductance regulator (CFTR) serine-511 by the combined action of tyrosine kinases and CK2: The implication of tyrosine-512 and phenylalanine-508 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Response to Wang et al.: Secreted protein kinases? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Detection of Phospho-Sites Generated by Protein Kinase CK2 in CFTR: Mechanistic Aspects of Thr1471 Phosphorylation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Heterogeneity of Ca2+ handling among and within Golgi compartments (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Peptide-based carbon nanotubes for mitochondrial targeting (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Myotonic dystrophy protein kinase (DMPK) prevents ROS-induced cell death by assembling a hexokinase II-Src complex on the mitochondrial surface (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Muscle phospholipid hydrolysis by Bothrops asper Asp49 and Lys49 phospholipase A2 myotoxins - Distinct mechanisms of action (Articolo in rivista) (Prodotto della ricerca)
• Botulinum neurotoxins (Articolo in rivista) (Prodotto della ricerca)
• Calpains participate in nerve terminal degeneration induced by spider and snake presynaptic neurotoxins (Articolo in rivista) (Prodotto della ricerca)
• Presynaptic functional trkB receptors mediate the release of excitatory neurotransmitters for primary afferent terminals in lamina II (substantia gelatinosa) of postnatal rat spinal cord. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination (Articolo in rivista) (Prodotto della ricerca)
• Pain sensitivity in mice lacking the Ca(v)2.1alpha1 subunit of P/Q-type Ca2+ channels. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• cAMP imaging of cells treated with pertussis toxin, cholera toxin, and anthrax edema toxin. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mechanisms of cytotoxicity of selected organogold(III) compounds (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Presynaptic neurotoxins with enzymatic activities. (Articolo in rivista) (Prodotto della ricerca)
• The prion protein and its paralogue Doppel affect calcium signaling in Chinese hamster ovary cells (Articolo in rivista) (Prodotto della ricerca)
• Cell entry and cAMP imaging of anthrax edema toxin. (Articolo in rivista) (Prodotto della ricerca)
• Ratio of lethal and edema factors in rabbit systemic anthrax. (Articolo in rivista) (Prodotto della ricerca)
• Anthrax toxins: A paradigm of bacterial immune suppression. (Articolo in rivista) (Prodotto della ricerca)
• Streptococcus pneumoniae induces mast cell degranulation. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondria and ischemia-reperfusion injury of the heart: fixing a hole. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cloning, expression, purification, and characterization of Streptococcus pneumoniae IgA1 protease. (Articolo in rivista) (Prodotto della ricerca)
• The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Protein kinase CK2: a newcomer in the 'druggable kinome'. (Articolo in rivista) (Prodotto della ricerca)
• The mitochondrial permeability transition from in vitro artifact to disease target. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Thrombin-induced tyrosine phosphorylation of HS1 in human platelets is sequentially catalyzed by Syk and Lyn tyrosine kinases and associated with the cellular migration of the protein. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Presynaptic enzymatic neurotoxins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The first armadillo repeat is involved in the recognition and regulation of beta-catenin phosphorylation by protein kinase CK1. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Electrophysiological characterization of the Cyclophilin D-deleted mitochondrial permeability transition pore. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Heterogeneous PrP C metabolism in skeletal muscle cells (Articolo in rivista) (Prodotto della ricerca)
• Anthrax edema factor, voltage-dependent binding to the protective antigen ion channel and comparison to LF binding. (Articolo in rivista) (Prodotto della ricerca)
• Stable peptide inhibitors prevent binding of lethal and oedema factors to protective antigen and neutralize anthrax toxin in vivo (Articolo in rivista) (Prodotto della ricerca)
• Ester-based precursors to increase the bioavailability of quercetin (Articolo in rivista) (Prodotto della ricerca)
• A novel potassium channel in lymphocyte mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• SNARE complexes and neuroexocytosis: how many, how close? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Impaired permeability to IP3 in a mutant connexin underlies recessive hereditary deafness. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Discrimination between two step in the mitochondrial permeability transition process (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Specific kinetic alterations of human CaV2.1 calcium channels produced by mutation S218L causing familial hemiplegic migraine and delayed cerebral edema and coma after minor head trauma (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Botulinal neurotoxins: revival of an old killer. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effect of auranofin on the mitochondrial generation of hydrogen peroxide. Role of thioredoxin reductase (Articolo in rivista) (Prodotto della ricerca)
• Presenilin-2 modulation of ER-mitochondria interactions: FAD mutations, mechanisms and pathological consequences. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial permeability transition: how many doors to the house? (Articolo in rivista) (Prodotto della ricerca)
• Extracellular copper ions regulate cellular prion protein (PrPC) expression and metabolism in neuronal cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Improved strategies for the delivery of GFP based Ca2+ sensors into the mitochondrial matrix. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Taipoxin induces F-actin fragmentation and enhances release of catecholamines in bovine chromaffin cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk (Articolo in rivista) (Prodotto della ricerca)
• Modal gating of human CaV2.1 (P/Q-type) calcium channels: I. The slow and the fast gating modes and their modulation by beta subunits. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Phosphorylation and activation of the atypical kinase p53-related protein kinase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Activity of rat cytosolic thioredoxin reductase is strongly decreased by (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• p66SHC promotes T cell apoptosis by inducing mitochondrial dysfunction and impaired Ca(2+) homeostasis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Enhanced astrocytic Ca2+ signals contribute to neuronal excitotoxicity after (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondria and cardioprotection. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pharmacological inhibition of protein kinase CK2 reverts the multidrug resistance phenotype of a CEM cell line characterized by high CK2 level. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anthrax lethal factor (LF) mediated block of the anthrax protective antigen (PA) ion channel: effect of ionic strength and voltage. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Reversible skeletal neuromuscular paralysis induced by different lysophospholipids. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A molecular model of the Vibrio cholerae cytolysin transmembrane pore. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Polyphenols reduce gastritis induced by Helicobacter pylori infection of VacA toxin administration in mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Protective activity and immunogenicity of two recombinant anthrax vaccines for veterinary use. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Calcium Influx and Mitochondrial Alterations at Synapses Exposed to Snake Neurotoxins or Their Phospholipid Hydrolysis Products. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A lysolecithin/fatty acid mixture promotes and then blocks neurotransmitter release at the Drosophila melanogaster larval neuromuscular junction (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Direct in vivo monitoring of sarcoplasmic reticulum Ca2+ and cytosolic cAMP dynamics in mouse skeletal muscle. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury (Articolo in rivista) (Prodotto della ricerca)
• After half a century mitochondrial calcium in- and efflux machineries reveal themselves (Articolo in rivista) (Prodotto della ricerca)
• Targeting of Cameleons to various subcellular compartments reveals a strict cytoplasmic/mitochondrial Ca2+ handling relationship in plant cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial Matrix Calcium Is an Activating Signal for Hormone Secretion (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial Ca2+ uptake contributes to buffering cytoplasmic Ca2+ peaks in cardiomyocytes (Articolo in rivista) (Prodotto della ricerca)
• Shedding light on the mitochondrial permeability transition (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Botulinum neurotoxins: genetic, structural and mechanistic insights (Articolo in rivista) (Prodotto della ricerca)
• Species-specific modulation of the mitochondrial permeability transition by norbormide (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Switch from inhibition to activation of the mitochondrial permeability transition during hematoporphyrin-mediated photooxidative stress. Unmasking pore-regulating external thiols (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Assessing the molecular basis for rat-selective induction of the mitochondrial permeability transition by norbormide (Articolo in rivista) (Prodotto della ricerca)
• An excitatory loop with astrocytes contributes to drive neurons to seizure threshold. (Articolo in rivista) (Prodotto della ricerca)
• Synaptobrevin2-expressing vesicles in rat astrocytes: insights into molecular characterization, dynamics and exocytosis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Enhancement of anxiety, facilitation of avoidance behavior, and occurrence of adult-onset obesity in mice lacking mitochondrial cyclophilin D (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The mitochondrial permeability transition pore and its adaptive responses in tumor cells (Articolo in rivista) (Prodotto della ricerca)
• Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction (Articolo in rivista) (Prodotto della ricerca)
• Oxidative stress in muscular dystrophy: from generic evidence to specific sources and targets (Articolo in rivista) (Prodotto della ricerca)
• Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential (Articolo in rivista) (Prodotto della ricerca)
• Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation (Articolo in rivista) (Prodotto della ricerca)
• Characterization of a plant glutamate receptor activity. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Role of gamma carboxylated Glu47 in connexin 26 hemichannel regulation by extracellular Ca2+: Insight from a local quantum chemistry study (Articolo in rivista) (Prodotto della ricerca)
• SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I (Articolo in rivista) (Prodotto della ricerca)
• UCP4C mediates uncoupled respiration in larvae of Drosophila melanogaster (Articolo in rivista) (Prodotto della ricerca)
• Regulation of the Mitochondrial Permeability Transition Pore by the Outer Membrane Does Not Involve the Peripheral Benzodiazepine Receptor ( Translocator Protein of 18 kDa ( TSPO)) (Articolo in rivista) (Prodotto della ricerca)
• Antamanide, a Derivative of Amanita phalloides, Is a Novel Inhibitor of the Mitochondrial Permeability Transition Pore (Articolo in rivista) (Prodotto della ricerca)
• Understanding protein kinase CK2 mis-regulation upon F508del CFTR expression (Articolo in rivista) (Prodotto della ricerca)
• ATP Site-Directed Inhibitors of Protein Kinase CK2: An Update (Articolo in rivista) (Prodotto della ricerca)
• Possible Role for Ca2+ in the pathophysiology of the prion protein? (Articolo in rivista) (Prodotto della ricerca)
• MITOCHONDRIAL CHANNELS: ION FLUXES AND MORE (Articolo in rivista) (Prodotto della ricerca)
• Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Differential phosphorylation of Akt1 and Akt2 by protein kinase CK2 may account for isoform specific functions (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• BAAV Mediated GJB2 Gene Transfer Restores Gap Junction Coupling in Cochlear Organotypic Cultures from Deaf Cx26Sox10Cre Mice (Articolo in rivista) (Prodotto della ricerca)
• Ca2+ homeostasis defects and hereditary hearing loss (Articolo in rivista) (Prodotto della ricerca)
• Multiphoton Fluorescence Microscopy with GRIN Objective Aberration Correction by Low Order Adaptive Optics (Articolo in rivista) (Prodotto della ricerca)
• The blockade of the neurotransmitter release apparatus by botulinum neurotoxins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A \"SYDE\" effect of hierarchical phosphorylation: possible relevance to the cystic fibrosis basic defect (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Casein kinase: the triple meaning of a misnomer (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The mitochondrial permeability transition pore and cyclophilin D in cardioprotection (Articolo in rivista) (Prodotto della ricerca)
• Thioredoxin and Its Reductase Are Present on Synaptic Vesicles, and Their Inhibition Prevents the Paralysis Induced by Botulinum Neurotoxins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Superiority of PLK-2 as alpha-synuclein phosphorylating agent relies on unique specificity determinants (Articolo in rivista) (Prodotto della ricerca)

Codice

• ME.P02.005.001 (literal)

Anno di chiusura previsto

• 2014-01-01T00:00:00+01:00 (literal)

Istituto esecutore

• Istituto di neuroscienze (IN) (Istituto)

Primo anno di attività

• 2005-01-01T00:00:00+01:00 (literal)

Abstract

• Le attività della commessa comprendono lo studio dei meccanismi cellulari e dell' eziogenesi di disordini del sistema nervoso, in particolare l'epilessia e l'emicrania. Vengono investigati anche aspetti del funzionamento e dello sviluppo dei sistemi uditivo ed olfattivo. Un programma di rilievo riguarda la segnalazione intracellulare - in particolare da Ca2+, cAMP, fosforilazioni – e il suo ruolo in disordini quali la sindrome di Alzheimer. Un altro filone si occupa di caratterizzare meccanicisticamente l'azione di neurotossine, di sfruttare la loro azione a scopi terapeutici, e di sviluppare inibitori dell'azione tossica. Importante è la ricerca su vari aspetti della fisiopatologia mitocondriale, sui fenomeni ossidoriduttivi nel funzionamento e in patologie cellulari e d'organo, in particolare in sindromi ischemiche, e sul ruolo fisiologico della proteina prionica. (literal)

Nome

• Neurobiologia e Neuropatologia (literal)

Descrizione

• Descrizione del modulo "Neurobiologia e Neuropatologia (ME.P02.005.001)" (Descrizione modulo)
• Descrizione dello stato di avanzamento delle attività del modulo "Neurobiologia e Neuropatologia (ME.P02.005.001)" (Descrizione stato avanzamento attività)
• Descrizione collaborazioni del modulo "Neurobiologia e Neuropatologia (ME.P02.005.001)" (Descrizione collaborazioni)

Modulo di

• Neurobiologia e Neuropatologia (ME.P02.005) (Commessa)

Gestore

• CESARE MONTECUCCO (Unità di personale esterno)

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Prodotto di

• Altered pain sensitivity in mice lacking the CaV2.1alpha1 subunit of P/Q-type Ca2+ channels (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Pain-related behaviours in mice lacking the CaV2.1alpha1 subunit of PQ-type Ca2+ channels (Contributo in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1301)
• Phosphate is essential for inhibition of the mitochondrial permeability transition pore by cyclosporin A and by cyclophilin D ablation. (Articolo in rivista) (Prodotto della ricerca)
• Differential effect of calcium ions on the cytosolic and mitochondrial thioredoxin reductase. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Astrocytic glutamate is not necessary for the generation of epileptiform neuronal activity in hippocampal slices. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pain sensitivity in mice lacking the Ca(v)2.1alpha1 subunit of P/Q-type Ca2+ channels. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Human doppel and prion protein share common membrane microdomains and internalization pathways. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Bax does not directly partecipate in the Ca2+ - induced permeability transition of isolated mitochondria (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Modal gating of human CaV2.1 (P/Q-type) calcium channels: I. The slow and the fast gating modes and their modulation by beta subunits. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Extracellular copper ions regulate cellular prion protein (PrPC) expression and metabolism in neuronal cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Improved strategies for the delivery of GFP based Ca2+ sensors into the mitochondrial matrix. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Impaired permeability to IP3 in a mutant connexin underlies recessive hereditary deafness. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Discrimination between two step in the mitochondrial permeability transition process (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Specific kinetic alterations of human CaV2.1 calcium channels produced by mutation S218L causing familial hemiplegic migraine and delayed cerebral edema and coma after minor head trauma (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Botulinal neurotoxins: revival of an old killer. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Heterogeneous PrP C metabolism in skeletal muscle cells (Articolo in rivista) (Prodotto della ricerca)
• Anthrax edema factor, voltage-dependent binding to the protective antigen ion channel and comparison to LF binding. (Articolo in rivista) (Prodotto della ricerca)
• Stable peptide inhibitors prevent binding of lethal and oedema factors to protective antigen and neutralize anthrax toxin in vivo (Articolo in rivista) (Prodotto della ricerca)
• Cell entry and cAMP imaging of anthrax edema toxin. (Articolo in rivista) (Prodotto della ricerca)
• Anthrax toxins: A paradigm of bacterial immune suppression. (Articolo in rivista) (Prodotto della ricerca)
• Streptococcus pneumoniae induces mast cell degranulation. (Articolo in rivista) (Prodotto della ricerca)
• Cloning, expression, purification, and characterization of Streptococcus pneumoniae IgA1 protease. (Articolo in rivista) (Prodotto della ricerca)
• Protein kinase CK2: a newcomer in the 'druggable kinome'. (Articolo in rivista) (Prodotto della ricerca)
• Presynaptic neurotoxins with enzymatic activities. (Articolo in rivista) (Prodotto della ricerca)
• cAMP imaging of cells treated with pertussis toxin, cholera toxin, and anthrax edema toxin. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Neuromuscular paralysis and recovery in mice injected with botulinum neurotoxins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondria-endoplasmic reticulum choreography: structure and signaling dynamics. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial Ca2+ as a key regulator of cell life and death.. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Direct Detection of Soil-Bound Prions (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Stable interactions between mitochondrial and endoplasmic reticulum allow rapid accumulation of calcium in a subpopultatin of mitochondria. (Articolo in rivista) (Prodotto della ricerca)
• Looking forward to seeing calcium. (Articolo in rivista) (Prodotto della ricerca)
• The Theodore Bucher lecture. Investigating signal transduction with genetically encoded fluorescent probes. (Articolo in rivista) (Prodotto della ricerca)
• Eukaryotic translation-initiation factor eIF2beta binds to protein kinase CK2: effects on CK2alpha activity. (Articolo in rivista) (Prodotto della ricerca)
• Correlation between fluidising effects on phospholipid membranes and mitochondrial respiration of propofol and p-nitrosophenol homologues. (Articolo in rivista) (Prodotto della ricerca)
• Emerging Protein Targets for Anticancer Metallodrugs: Inhibition of Thioredoxin Reductase and Cathepsin B by Antitumor Ruthenium (II)-Arene Compounds. (Articolo in rivista) (Prodotto della ricerca)
• Src-Tyrosine kinases are major agents in mitochondrial tyrosine phosphorylation. (Articolo in rivista) (Prodotto della ricerca)
• Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels. (Articolo in rivista) (Prodotto della ricerca)
• Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect fuctional links with cystic fibrosis pathogenesis. (Articolo in rivista) (Prodotto della ricerca)
• Mass spectrometry analysis of a protein kinase CK2beta subunit interactome isolated from mouse brain by affinity chromatography. (Articolo in rivista) (Prodotto della ricerca)
• Ca2+ oscillation frequency decoding in cardiac cell hypertrophy: role of calcineurin/NFAT as Ca2+ signal integrators. (Articolo in rivista) (Prodotto della ricerca)
• Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage. (Articolo in rivista) (Prodotto della ricerca)
• Modulation of mitochondrial K+ permeability and reactive oxygen species production by the p13 protein of human T-cell leukemia virus type 1. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cyclophilin D modulates mitochondrial F0F1-ATP aynthase by interacting with the lateral stalk of the complex. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Treatment of human cancer cells with selenite or tellurite in combination with auranofin enhances (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mass spectrometry analysis of the phospholipase A(2) activity of snake pre-synaptic neurotoxins in cultured neurons. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Neurotoxicity of inverted-cone shaped lipids (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Measurements of mitochondrial calcium in vivo. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Lysophospholipids are evolutionary ancient venom components. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondria: The calcium connection. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Functional and structural alterations in the endoplasmic reticulum and mitochondria during apoptosis triggered by C-2-ceramide and CD95/APO-1/FAS receptor stimulation. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Myosin Va cooperates with PKA RIa to mediate maintenance of the endplate in vivo. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Addiction to protein kinase CK2: a common denominator of diverse cancer cells? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cellular prion protein promotes regeneration of adult muscle tissue. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The mitochondrial permeability transition from yeast to mammals. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cyclophilin D in mitochondrial pathophysiology. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial thioredoxin reductase: purification, inhibitor studies, and role in cell signaling. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Antamanide, a Derivative of Amanita phalloides, Is a Novel Inhibitor of the Mitochondrial Permeability Transition Pore (Articolo in rivista) (Prodotto della ricerca)
• Snake PLA2 neurotoxins enter neurons, bind specifically to mitochondria and open their transition pores. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Calpain activity contributes to the control of SNAP-25 levels in neurons. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Copper (II) binding to the human Doppel protein may mark its functional diversità from the prion protein (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The modulation of thiol redox state affects the production and metabolism and hydrogen peroxide by heart mitochondrial. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial function and myocardial aging. A critical analysis of the role of permeability transition (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Calcium Influx and Mitochondrial Alterations at Synapses Exposed to Snake Neurotoxins or Their Phospholipid Hydrolysis Products. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A lysolecithin/fatty acid mixture promotes and then blocks neurotransmitter release at the Drosophila melanogaster larval neuromuscular junction (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Direct in vivo monitoring of sarcoplasmic reticulum Ca2+ and cytosolic cAMP dynamics in mouse skeletal muscle. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anthrax lethal factor (LF) mediated block of the anthrax protective antigen (PA) ion channel: effect of ionic strength and voltage. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Reversible skeletal neuromuscular paralysis induced by different lysophospholipids. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A molecular model of the Vibrio cholerae cytolysin transmembrane pore. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Polyphenols reduce gastritis induced by Helicobacter pylori infection of VacA toxin administration in mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Protective activity and immunogenicity of two recombinant anthrax vaccines for veterinary use. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Activity of rat cytosolic thioredoxin reductase is strongly decreased by (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• p66SHC promotes T cell apoptosis by inducing mitochondrial dysfunction and impaired Ca(2+) homeostasis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Enhanced astrocytic Ca2+ signals contribute to neuronal excitotoxicity after (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondria and cardioprotection. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pharmacological inhibition of protein kinase CK2 reverts the multidrug resistance phenotype of a CEM cell line characterized by high CK2 level. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Phosphorylation and activation of the atypical kinase p53-related protein kinase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effect of auranofin on the mitochondrial generation of hydrogen peroxide. Role of thioredoxin reductase (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial permeability transition: how many doors to the house? (Articolo in rivista) (Prodotto della ricerca)
• A novel potassium channel in lymphocyte mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• SNARE complexes and neuroexocytosis: how many, how close? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Ester-based precursors to increase the bioavailability of quercetin (Articolo in rivista) (Prodotto della ricerca)
• Mitochondria and ischemia-reperfusion injury of the heart: fixing a hole. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The mitochondrial permeability transition from in vitro artifact to disease target. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Presynaptic enzymatic neurotoxins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The first armadillo repeat is involved in the recognition and regulation of beta-catenin phosphorylation by protein kinase CK1. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Electrophysiological characterization of the Cyclophilin D-deleted mitochondrial permeability transition pore. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The prion protein and its paralogue Doppel affect calcium signaling in Chinese hamster ovary cells (Articolo in rivista) (Prodotto della ricerca)
• Ratio of lethal and edema factors in rabbit systemic anthrax. (Articolo in rivista) (Prodotto della ricerca)
• Gold(III)-dithiocarbamato complexes induce cancer cell death triggered by (Articolo in rivista) (Prodotto della ricerca)
• The crystal structure of CagS from the Helicobacter pylori pathogenicity island. (Articolo in rivista) (Prodotto della ricerca)
• Peculiar binding of botulinum neurotoxins. (Articolo in rivista) (Prodotto della ricerca)
• Human Keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores. (Articolo in rivista) (Prodotto della ricerca)
• Tyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic actvity. (Articolo in rivista) (Prodotto della ricerca)
• Binding of N-terminal fragments of anthraz edema factor (EF (N)) and lethal factor (LF (N)) to the protective antigen pore. (Articolo in rivista) (Prodotto della ricerca)
• Inheruted neuronal ion channelopathies: new windows on complex neurological diseases. (Articolo in rivista) (Prodotto della ricerca)
• Thiol chemistry in peroxidase catalysis and redox signaling. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Gold(I) complexes determine apoptosis with limited oxidative stress in Jurkat T cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Altered threshold of the mitochondrial permeability transition pore in Ullrich congenital muscular dystrophy. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• High glucose induces adipogenic differentiation of muscle-derived stem cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cardiac cell hypertrophy in vitro: role of calcineurin/NFAT as Ca2+ signal integrators. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A mitochondriotropic derivative of quercetin: a strategy to increase the effectiveness of polyphenols. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Development of mitochondrial-targeted derivatives o resveratrol. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The role of autophagy in neonatal tissues: just a response to starvation? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pathophysiology of mitochondrial volume homeostasis: Potassium transport and permeability transition. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Respiratory Complex I Dysfunction Due to Mitochondrial DNA Mutations Shifts the Voltage Threshold for Opening of the Permeability Transition Pore toward Resting Levels. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A CaPful of mechanisms regulating the mitochondrial permeability transition (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Different mechanisms of inhibition of nerve terminals by botulinum and snake presynaptic neurotoxins. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Odorant receptors at the growth cone are coupled to localized cAMP and Ca2+ increases (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• From cell protection to death: may Ca2+ signals explain the chameleonic attributes of the mammalian prion protein? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Novel channels of the inner mitochondrial membrane (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Intermediate conductance Ca2+-activated potassium channel (KCa3.1) in the inner mitochondrial membrane of human colon cancer cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Quercetin can act either as an inhibitor or an inducer of the Mitochondrial Permeability Transition Pore: a demonstration of the ambivalent redox character of polyphenols (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Soluble polyphenols: synthesis and bioavailability of 3,4',5-tri(alpha-D-glucose-3-O-succinyl)resveratrol. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Bothrop snake myotoxins induce a large efflux of ATP and potassium with spreading of cell damage and pain. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Imaging the cell entry of the anthrax oedema and lethal toxins with fluorescent protein chimeras. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A new experimental model of focal seizures in the entorhinal cortex (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial matrix pH controls oxidative phosphorylation and metabolism-secretion coupling in INS-1E clonal beta cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Ca2+ hot spots on the mitochondrial surface are generated by Ca2+ mobilization from stores, but not by activation of store operated Ca2+ channels. (Articolo in rivista) (Prodotto della ricerca)
• Unique characteristics of Ca2+ homeostasis of the trans-Golgi compartment. (Articolo in rivista) (Prodotto della ricerca)
• Golgi apparatus casein kinase phosphorylates bioactive Ser-6 of bone morphogenetic protein 15 and growth and differentiation factor 9. (Articolo in rivista) (Prodotto della ricerca)
• Prion and TNF(alpha): TAC(E)it agreement between the prion protein and cell signaling. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial Ca2+ transport and permeability transition in zebrafish (Danio rerio) (Articolo in rivista) (Prodotto della ricerca)
• Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition. (Articolo in rivista) (Prodotto della ricerca)
• Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity and thioredoxin reductase inhibition of a series of gold(I) complexes containing hydrophilic phosphine ligands (Articolo in rivista) (Prodotto della ricerca)
• Thiol redox systems and protein kinases in hepatic stellate cell regulatory processes. (Articolo in rivista) (Prodotto della ricerca)
• Redox regulation of T-cell turnover by the p13 protein of human T-cell leukemia virus type 1: distinct effects in primary versus transformed cells. (Articolo in rivista) (Prodotto della ricerca)
• ATP-sensitive cation channel in wheat (Triticum durum Desf.): identification and characterization of a plant mitochondrial channel by patch-clamp. (Articolo in rivista) (Prodotto della ricerca)
• Regioselective O-derivatization of quercetin via ester intermediates. An improved synthesis of rhamnetin and development of a new mitochondriotropic derivative. (Articolo in rivista) (Prodotto della ricerca)
• Role of Kv1.3 mitochondrial potassium channel in apoptotic signalling in lymphocytes. (Articolo in rivista) (Prodotto della ricerca)
• Impact of mitochondriotropic quercetin derivatives on mitochondria. (Articolo in rivista) (Prodotto della ricerca)
• Actin reorganization is abnormal and cellular ATP is decreased in Hailey-Hayley keratinocytes. (Articolo in rivista) (Prodotto della ricerca)
• One-thousand-and-one substrates of protein kinase CK2? (Articolo in rivista) (Prodotto della ricerca)
• Plant polyphenols inhibit VacA, toxin secreted by the gastic pathogen Helecobacter pylory. (Articolo in rivista) (Prodotto della ricerca)
• Cross-talk between PDGF and S1P signalling elucidates the inhibitory effect and potential antifibrotic action of the immunomodulator FTY720 in activated HSC-cultures. (Articolo in rivista) (Prodotto della ricerca)
• The regulatory beta subunit of protein kinase CK2 contributes to the recognition of the substrate consensus sequence. A study with an eIF2 beta-derived peptide. (Articolo in rivista) (Prodotto della ricerca)
• The selectivity of inhibitors of protein kinase CK2: an uptade. (Articolo in rivista) (Prodotto della ricerca)
• Comparative analysis of CK2 expression and function in tumor cell lines displaying sensitivity vs. resistance to chemical induced apoptosis. (Articolo in rivista) (Prodotto della ricerca)
• Phosphorylation and activation of the atypical kinase P53-related protein kinase (PRPK) by Akt/PKB. (Articolo in rivista) (Prodotto della ricerca)
• Calcium dynamics in the peroxisomal lumen of living cells. (Articolo in rivista) (Prodotto della ricerca)
• A maxi chloride channel in the inner membrane of mammalian mitochondria. (Articolo in rivista) (Prodotto della ricerca)
• Developmental Shift of Cyclophilin D Contribution to Hypoxic-Ischemic Brain Injury. (Articolo in rivista) (Prodotto della ricerca)
• The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondria and vascular pathology. (Articolo in rivista) (Prodotto della ricerca)
• The anthrax lethal factor and its MAPK kinase-specific metalloprotease activity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Calcium overload in nerve terminals of cultured neurons intoxicated by alpha-latrotoxin and snake PLA2 neurotoxins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Dephosphorylation and inactivation of Akt/PKB is counteracted by protein kinase CK2 in HEK 293T cells. (Articolo in rivista) (Prodotto della ricerca)
• Calcium elevation in mitochondria is the main Ca2+ requirement for mitochondrial permeability transition pore (mPTP) opening. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Is indeed the prion protein an Harlequin servant of “many” masters? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Enhanced excitatory transmission at cortical synapses as the basic for facilitated spreading depression in Ca(v) 2.1 knockin migraine mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Heterogeneity and standardization of Phase II metabolism in cultured cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Absorption and metabolism of resveratrol carboxyesters and methanesulfonate by explanted rat intestinal segments. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Glutamate-mediated astrocyte-to-neuron signalling in the rat dorsal horn. (Articolo in rivista) (Prodotto della ricerca)
• The contribution of astrocyte signalling to neurovascular coupling. (Articolo in rivista) (Prodotto della ricerca)
• Astrocyte dysfunction in epilepsy. (Articolo in rivista) (Prodotto della ricerca)
• Cystic fibrosis transmembrane regulator fragments with the Phe508 deletion exert a dual allosteric control over the master kinase CK2. (Articolo in rivista) (Prodotto della ricerca)
• Signal transduction to the permeability transition pore. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrially targeted anti-cancer agents (Articolo in rivista) (Prodotto della ricerca)
• Contribution of voltage-gated potassium channels to the regulation of apoptosis. (Articolo in rivista) (Prodotto della ricerca)
• Electrophysiology clarifies the megariddles of the mitochondrial permeability transition pore. (Articolo in rivista) (Prodotto della ricerca)
• An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca2+-activated K+ channel mtKCa3.1. (Articolo in rivista) (Prodotto della ricerca)
• Presynaptic functional trkB receptors mediate the release of excitatory neurotransmitters for primary afferent terminals in lamina II (substantia gelatinosa) of postnatal rat spinal cord. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Altered sensitivity to nociceptive stimuli in mice lacking the CaV2.1ƒalpha1 subunit of P/Q-type Ca2+ channels. (Contributo in atti di convegno) (Prodotto della ricerca)
• Behavioural effects due to injection of botulinum neurotoxins in central nervous system (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Central injection of botulinum neurotoxins: toxicology and behavioural effects in mice (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Altered sensitivity to nociception stimuli in mice lacking the CaV2.1alpha1 subunit of PQ-type Ca2+ channels (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• pH dependence of human CaV2.1 channels and its alteration by a familial hemiplegic migraine mutation (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• pH dependence of human CaV2.1 channels and its alteration by a familial hemiplegic migraine mutation (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• PH dependence of human CaV2.1 channels and its alteration by a familial hemiplegic migraine mutation. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Central injection of botulinum neurotoxins: toxicology, brain localization and bahavioural effects in mice (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Toxicological and behavioural effects of botulinum neurotoxins injected in central nervous system (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Mechanisms of cytotoxicity of selected organogold(III) compounds (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Assessing the molecular basis for rat-selective induction of the mitochondrial permeability transition by norbormide (Articolo in rivista) (Prodotto della ricerca)
• An excitatory loop with astrocytes contributes to drive neurons to seizure threshold. (Articolo in rivista) (Prodotto della ricerca)
• Red wine and green tea reduce H pylori- or VacA-induced gastritis in a mouse model (Articolo in rivista) (Prodotto della ricerca)
• Taipoxin induces F-actin fragmentation and enhances release of catecholamines in bovine chromaffin cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Apoptosis to necrosis switching downstream of apoptosome formation requires inhibition of both glycolysis and oxidative phosphorylation in a BCL-X-L- and PKB/AKT-independent fashion (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Properties of Ca2+ Transport in Mitochondria of Drosophila melanogaster (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial dysfunction in the pathogenesis of Ullrich congenital muscular dystrophy and prospective therapy with cyclosporins. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cyclosporin A corrects mitochondrial dysfunction and muscle apoptosis in patients with collagen VI myopathies. (Articolo in rivista) (Prodotto della ricerca)
• Thrombin-induced tyrosine phosphorylation of HS1 in human platelets is sequentially catalyzed by Syk and Lyn tyrosine kinases and associated with the cellular migration of the protein. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK-MAPK activation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• High cortical spreading depression susceptibility and migraine-associated symptoms in Ca(v)2.1 S218L mice. (Articolo in rivista) (Prodotto della ricerca)
• Enhancement of anxiety, facilitation of avoidance behavior, and occurrence of adult-onset obesity in mice lacking mitochondrial cyclophilin D (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synaptobrevin2-expressing vesicles in rat astrocytes: insights into molecular characterization, dynamics and exocytosis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Species-specific modulation of the mitochondrial permeability transition by norbormide (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Switch from inhibition to activation of the mitochondrial permeability transition during hematoporphyrin-mediated photooxidative stress. Unmasking pore-regulating external thiols (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Characterization of a plant glutamate receptor activity. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects in Col6a1(-/-) myopathic mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Traffic of botulinum toxins A and E in excitatory and inhibitory neurons. (Articolo in rivista) (Prodotto della ricerca)
• Shedding light on the mitochondrial permeability transition (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A glutamine synthetase inhibitor increases survival and decreases cytokine response in a mouse model of acute liver failure (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial Ca2+ Uptake Induces Cyclic AMP Generation in the Matrix and Modulates Organelle ATP Levels (Articolo in rivista) (Prodotto della ricerca)
• Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain (Articolo in rivista) (Prodotto della ricerca)
• Evidence for a radial snare super-complex mediating neurotransmitter release at the drosophila neuromuscular junction (Articolo in rivista) (Prodotto della ricerca)
• The thioredoxin reductase-thioredoxin system is involved in the entry of tetanus and botulinum neurotoxins in the cytosol of nerve terminals (Articolo in rivista) (Prodotto della ricerca)
• CK1delta Kinase Activity Is Modulated by Chk1-Mediated Phosphorylation (Articolo in rivista) (Prodotto della ricerca)
• Kinase CK2 inhibition: An update (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Exploiting the repertoire of CK2 inhibitors to target DYRK and PIM kinases (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Secreted protein kinases? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• CFTR mutations altering CFTR fragmentation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pathophysiology of migraine (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Calcium channels and migraine (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Intracellular ion channels and cancer (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Acetal derivatives as prodrugs of resveratrol (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1.3, as a new and selective therapeutic strategy in chronic lymphocytic leukemia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Retinal pigment epithelium (RPE) exosomes contain signaling phosphoproteins affected by oxidative stress (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Dimers of mitochondrial ATP synthase form the permeability transition pore (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Ca 2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2 (Articolo in rivista) (Prodotto della ricerca)
• No evidence for inositol 1,4,5-trisphosphate-dependent Ca2+ release in isolated fibers of adult mouse skeletal muscle (Articolo in rivista) (Prodotto della ricerca)
• Altered store operated calcium entry increases cyclic 3',5'-adenosine monophosphate production and extracellular signal-regulated kinases 1 and 2 phosphorylation in polycystin-2-defective cholangiocytes (Articolo in rivista) (Prodotto della ricerca)
• Ca2+ signalling in the Golgi apparatus (Articolo in rivista) (Prodotto della ricerca)
• Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury (Articolo in rivista) (Prodotto della ricerca)
• The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination (Articolo in rivista) (Prodotto della ricerca)
• Muscle phospholipid hydrolysis by Bothrops asper Asp49 and Lys49 phospholipase A2 myotoxins - Distinct mechanisms of action (Articolo in rivista) (Prodotto della ricerca)
• Botulinum neurotoxins (Articolo in rivista) (Prodotto della ricerca)
• Calpains participate in nerve terminal degeneration induced by spider and snake presynaptic neurotoxins (Articolo in rivista) (Prodotto della ricerca)
• Aberrant signalling by protein kinase CK2 in imatinib-resistant chronic myeloid leukaemia cells: Biochemical evidence and therapeutic perspectives (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Phosphorylation of cystic fibrosis transmembrane conductance regulator (CFTR) serine-511 by the combined action of tyrosine kinases and CK2: The implication of tyrosine-512 and phenylalanine-508 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Response to Wang et al.: Secreted protein kinases? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Detection of Phospho-Sites Generated by Protein Kinase CK2 in CFTR: Mechanistic Aspects of Thr1471 Phosphorylation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Heterogeneity of Ca2+ handling among and within Golgi compartments (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Peptide-based carbon nanotubes for mitochondrial targeting (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Myotonic dystrophy protein kinase (DMPK) prevents ROS-induced cell death by assembling a hexokinase II-Src complex on the mitochondrial surface (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Fluorescent silver(i) and gold(i)-N-heterocyclic carbene complexes with cytotoxic properties: Mechanistic insights (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Principles in redox signaling: From chemistry to functional significance (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The 3.5 angstrom X-ray structure of the human connexin26 gap junction channel is unlikely that of a fully open channel (Articolo in rivista) (Prodotto della ricerca)
• Monoamine oxidase inhibition prevents mitochondrial dysfunction and apoptosis in myoblasts from patients with collagen VI myopathies (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• NIM811, a cyclophilin inhibitor without immunosuppressive activity, is beneficial in collagen VI congenital muscular dystrophy models (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• MITOCHONDRIAL CHANNELS: ION FLUXES AND MORE (Articolo in rivista) (Prodotto della ricerca)
• Targeting of Cameleons to various subcellular compartments reveals a strict cytoplasmic/mitochondrial Ca2+ handling relationship in plant cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• After half a century mitochondrial calcium in- and efflux machineries reveal themselves (Articolo in rivista) (Prodotto della ricerca)
• Botulinum neurotoxins: genetic, structural and mechanistic insights (Articolo in rivista) (Prodotto della ricerca)
• Molecular dynamics simulations highlight structural and functional alterations in deafness-related M34T mutation of connexin 26 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mechanism underlying unaltered cortical inhibitory synaptic transmission in contrast with enhanced excitatory transmission in Ca(V)2.1 knockin migraine mice (Articolo in rivista) (Prodotto della ricerca)
• Synthesis and Properties of a Selective Inhibitor of Homeodomain-Interacting Protein Kinase 2 (HIPK2) (Articolo in rivista) (Prodotto della ricerca)
• Identification of the PLK2-Dependent Phosphopeptidome by Quantitative Proteomics (Articolo in rivista) (Prodotto della ricerca)
• CK2 involvement in ESCRT-III complex phosphorylation (Articolo in rivista) (Prodotto della ricerca)
• The lysine-specific demethylase 1 is a novel substrate of protein kinase CK2 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Migraine: a disorder of brain excitatory-inhibitory balance? (Articolo in rivista) (Prodotto della ricerca)
• Permeation Pathway of Homomeric Connexin 26 and Connexin 30 Channels Investigated by Molecular Dynamics (Articolo in rivista) (Prodotto della ricerca)
• Reduced phosphatidylinositol 4,5-bisphosphate synthesis impairs inner ear Ca2+ signaling and high-frequency hearing acquisition (Articolo in rivista) (Prodotto della ricerca)
• The Pathophysiology of LETM1 (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial Ca2+ homeostasis: mechanism, role, and tissue specificities (Articolo in rivista) (Prodotto della ricerca)
• Inhibition of complex I regulates the mitochondrial permeability transition through a phosphate-sensitive inhibitory site masked by cyclophilin D (Articolo in rivista) (Prodotto della ricerca)
• Preface to Mitochondria and Cardioprotection (Articolo in rivista) (Prodotto della ricerca)
• Construction and test of a GRIN-based optical objective (Articolo in rivista) (Prodotto della ricerca)
• Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk (Articolo in rivista) (Prodotto della ricerca)
• Presenilin-2 modulation of ER-mitochondria interactions: FAD mutations, mechanisms and pathological consequences. (Articolo in rivista) (Prodotto della ricerca)
• Botulinum neurotoxin type A is internalized and translocated from small synaptic vesicles at the neuromuscular junction (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Why myotoxin-containing snake venoms possess powerful nucleotidases? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Botulinum neurotoxin serotype D is poorly effective in humans: An in vivo electrophysiological study (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Time course and temperature dependence of the membrane translocation of tetanus and botulinum neurotoxins C and D in neurons (Articolo in rivista) (Prodotto della ricerca)
• Tetanus neurotoxin (Articolo in rivista) (Prodotto della ricerca)
• Pyrvinium pamoate does not activate protein kinase CK1, but promotes Akt/PKB down-regulation and GSK3 activation (Articolo in rivista) (Prodotto della ricerca)
• Quercetin mitochondriotropic derivatives antagonize nitrate tolerance and endothelial dysfunction of isolated rat aorta rings (Articolo in rivista) (Prodotto della ricerca)
• The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase (Articolo in rivista) (Prodotto della ricerca)
• Fast spiking interneuron control of seizure propagation in a cortical slice model of focal epilepsy (Articolo in rivista) (Prodotto della ricerca)
• A rapid and sensitive assay of intercellular coupling by voltage imaging of gap junction networks (Articolo in rivista) (Prodotto della ricerca)
• ATP-dependent intercellular Ca2+ signaling in the developing cochlea: Facts, fantasies and perspectives (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial Ca2+ uptake contributes to buffering cytoplasmic Ca2+ peaks in cardiomyocytes (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial Matrix Calcium Is an Activating Signal for Hormone Secretion (Articolo in rivista) (Prodotto della ricerca)
• beta(2)-Adrenoceptors, NADPH oxidase, ROS and p38 MAPK: another 'radical' road to heart failure? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Thioredoxin and Its Reductase Are Present on Synaptic Vesicles, and Their Inhibition Prevents the Paralysis Induced by Botulinum Neurotoxins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The blockade of the neurotransmitter release apparatus by botulinum neurotoxins (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A \"SYDE\" effect of hierarchical phosphorylation: possible relevance to the cystic fibrosis basic defect (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Casein kinase: the triple meaning of a misnomer (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Differential phosphorylation of Akt1 and Akt2 by protein kinase CK2 may account for isoform specific functions (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Induction of the permeability transition pore in cells depleted of mitochondrial DNA (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The permeability transition pore as a Ca2+ release channel: New answers to an old question (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effects of the CK2 Inhibitors CX-4945 and CX-5011 on Drug-Resistant Cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Activation of the mitochondrial permeability transition pore modulates Ca2+ responses to physiological stimuli in adult neurons (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Double anchorage to the membrane and intact inter-chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Translocation of signalling proteins to the plasma membrane revealed by a new bioluminescent procedure (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Propagation of chaos and commotion in the wake of cortical spreading depression and spreading depolarizations (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Role of gamma carboxylated Glu47 in connexin 26 hemichannel regulation by extracellular Ca2+: Insight from a local quantum chemistry study (Articolo in rivista) (Prodotto della ricerca)
• SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I (Articolo in rivista) (Prodotto della ricerca)
• UCP4C mediates uncoupled respiration in larvae of Drosophila melanogaster (Articolo in rivista) (Prodotto della ricerca)
• Regulation of the Mitochondrial Permeability Transition Pore by the Outer Membrane Does Not Involve the Peripheral Benzodiazepine Receptor ( Translocator Protein of 18 kDa ( TSPO)) (Articolo in rivista) (Prodotto della ricerca)
• The mitochondrial permeability transition pore and its adaptive responses in tumor cells (Articolo in rivista) (Prodotto della ricerca)
• Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction (Articolo in rivista) (Prodotto della ricerca)
• Oxidative stress in muscular dystrophy: from generic evidence to specific sources and targets (Articolo in rivista) (Prodotto della ricerca)
• Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential (Articolo in rivista) (Prodotto della ricerca)
• Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation (Articolo in rivista) (Prodotto della ricerca)
• Superiority of PLK-2 as alpha-synuclein phosphorylating agent relies on unique specificity determinants (Articolo in rivista) (Prodotto della ricerca)
• The mitochondrial permeability transition pore and cyclophilin D in cardioprotection (Articolo in rivista) (Prodotto della ricerca)
• BAAV Mediated GJB2 Gene Transfer Restores Gap Junction Coupling in Cochlear Organotypic Cultures from Deaf Cx26Sox10Cre Mice (Articolo in rivista) (Prodotto della ricerca)
• Ca2+ homeostasis defects and hereditary hearing loss (Articolo in rivista) (Prodotto della ricerca)
• Multiphoton Fluorescence Microscopy with GRIN Objective Aberration Correction by Low Order Adaptive Optics (Articolo in rivista) (Prodotto della ricerca)
• Understanding protein kinase CK2 mis-regulation upon F508del CFTR expression (Articolo in rivista) (Prodotto della ricerca)
• ATP Site-Directed Inhibitors of Protein Kinase CK2: An Update (Articolo in rivista) (Prodotto della ricerca)
• Possible Role for Ca2+ in the pathophysiology of the prion protein? (Articolo in rivista) (Prodotto della ricerca)
• Neurotoxicity of European viperids in Italy: Pavia Poison Control Centre case series 2001-2011 (Articolo in rivista) (Prodotto della ricerca)
• http://www.cnr.it/ontology/cnr/individuo/prodotto/ID321647
• http://www.cnr.it/ontology/cnr/individuo/prodotto/ID321646

Modulo

• Neurobiologia e Neuropatologia (ME.P02.005) (Commessa)

Gestore di

• CESARE MONTECUCCO (Unità di personale esterno)

Istituto esecutore di

• Istituto di neuroscienze (IN) (Istituto)

Descrizione di

• Descrizione collaborazioni del modulo "Neurobiologia e Neuropatologia (ME.P02.005.001)" (Descrizione collaborazioni)
• Descrizione dello stato di avanzamento delle attività del modulo "Neurobiologia e Neuropatologia (ME.P02.005.001)" (Descrizione stato avanzamento attività)
• Descrizione del modulo "Neurobiologia e Neuropatologia (ME.P02.005.001)" (Descrizione modulo)