Interrelazione nucleo/citoplasma/mitocondri nell'omeostasi cellulare. (SV.P15.003.001)

Type

• Modulo (Classe)

Label

• Interrelazione nucleo/citoplasma/mitocondri nell'omeostasi cellulare. (SV.P15.003.001) (literal)

Prodotto

• Mitochondrial dysfunction in cancer chemoresistance (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Tissue-specific mtDNA abundance from exome data and its correlation with mitochondrial transcription, mass and respiratory activity. (Articolo in rivista) (Prodotto della ricerca)
• Il lievito Saccharomyces cerevisiae: un modello di eucariote unicellulare idoneo per studi di diversità genotipica e fenotipica. (Comunicazione a convegno) (Prodotto della ricerca)
• A new detergent to purify CNS myelin basic protein isoforms in lipid-bound form. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• On the Spontaneous Adherence of Myelin Basic Protein to Normal Lymphocytes. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Interaction of Cations with Lipid Free Myelin Basic Protein: A Spectroscopic Study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Myelin basic protein interaction with zinc and phosphate: fluorescence studies on the water-soluble form of the protein. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 21-hydroxylase deficiency in Italy: a distinct pattern of CYP21 mutations in a sample from southern Italy (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Lack of cytochrome c release en route to acetic acid-induced programmed cell death in caspase-like gene knockout yeast cells. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• The molecular evolution of B6 enzymes: ribonuclease A as a model pyridoxal-5’-phosphate-dependent protoenzyme. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Programmed cell death in Saccharomyces cerevisiae. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Glutamate neurotoxicity, oxidative stress and mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• How Saccharomyces cerevisiae cells die as a function of time in response to acetic acid: relations among ROS, cytochrome c and caspase-like activity. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Characterization of the CYP21 gene 5' flanking region in patients affected by 21-OH deficiency. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Yeast programmed cell death triggered by aceti acid: ROS involvement and cytochrome c release. (Comunicazione a convegno) (Prodotto della ricerca)
• NITRIC OXIDE SYNTHASE UPREGULATION IN THE EARLY PHASE OF CEREBELLAR GRANULE CELLS APOPTOSIS (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Preservation of mitochondrial functional integrity in mitochondria isolated from small cryopreserved mouse brain areas (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The mitochondrial genome encodes abundant small noncoding RNAs. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• IMPAIRMENT OF OXIDATIVE PHOSPHORYLATION APPARATUS AND OVERPRODUCTION OF RADICAL SPECIES BY MITOCHONDRIA IN DOWN SYNDROME (Abstract/Comunicazione in atti di convegno) (Prodotto della ricerca)
• Cytochrome c, released from cerebellar granule cells undergoing apoptosis or excytotoxic death, can generate protonmotive force and drive ATP synthesis in isolated mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anion transport in rat brain mitochondria: fumarate uptake via the dicarboxylate carrier. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Ornithine/phosphate antiport in rat kidney mitochondria. Some characteristics of the process. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial retrograde signaling contributes to acetic acid-induced programmed cell death resistance in yeast (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• IL MITOCONDRIO - Permeabilità e metabolismo (Curatela) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1501)
• Glutamine transport in normal and acidotic rat kidney mitochondria (Articolo in rivista) (Prodotto della ricerca)
• SPECTROSCOPIC STUDY OF HYDROXYPROLINE TRANSPORT IN RAT-KIDNEY MITOCHONDRIA (Articolo in rivista) (Prodotto della ricerca)
• Characterization of phenylketonuria alleles in the Italian population. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The mechanism of proline/glutamate antiport in rat kidney mitochondria. Energy dependence and glutamate-carrier involvement (Articolo in rivista) (Prodotto della ricerca)
• Expression of cDNAs encoding the precursor and the mature form of chicken mitochondrial aspartate aminotransferase in Escherichia coli. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Fumarate permeation in rat liver mitochondria: fumarate/malate and fumarate/phosphate translocators. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Rapid uncoupling of oxidative phosphorylation accompanies glutamate toxicity in rat cerebellar granule cells (Articolo in rivista) (Prodotto della ricerca)
• Carrier-mediated transport controls hydroxyproline catabolism in heart mitochondria from spontaneously hypertensive rat (Articolo in rivista) (Prodotto della ricerca)
• Dissecting the molecular mechanism by which NH2htau and Abeta1-42 peptides impair mitochondrial ANT-1 in Alzheimer disease (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Glutamate stimulates 2-deoxyglucose uptake in rat cerebellar granule cells. (Articolo in rivista) (Prodotto della ricerca)
• Metabolite transport in rat kidney mitochondria: ornithine/phosphate translocator. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The in vitro-synthesized precursor and mature mitochondrial aspartate aminotransferase share the same import pathway in isolated mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Phenylketonuria mutations and linked haplotypes in the Lithuanian population: origin of the most common R408W mutation. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Increase in the ADP/ATP exchange in rat liver mitochondria irradiated in vitro by helium-neon laser. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• UPTAKE OF ASPARTATE-AMINOTRANSFERASE INTO MITOCHONDRIA INVITRO CAUSES EFFLUX OF MALATE-DEHYDROGENASE AND VICE VERSA (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Haematoporphyrin derivative (Photofrin II) photosensitization of isolated mitochondria: inhibition of ADP/ATP translocator. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The STR252-IVS10nt546-VNTR7 phenylalanine hydroxylase minihaplotype in five Mediterranean samples. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carrier thiols are targets of Photofrin II photosensitization of isolated rat liver mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effects of rhodamine 123 in the dark and after irradiation on mitochondrial energy metabolism. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Phenylalanine and tyrosine metabolism in PKU heterozygotes: influence of different PAH mutations. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Phenylketonuria in Italy: distinct distribution pattern of three mutations of the phenylalanine hydroxylase gene. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The apoptosis/necrosis transition in cerebellar granule cells depends on the mutual relationship of the antioxidant and the proteolytic systems which regulate ROS production and cytochrome c release en route to death. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A sensitive method to assay the xanthine oxidase activity in primary cultures of cerebellar granule cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Kinetic properties and thermal stabilities of mutant forms of mitochondrial aspartate aminotransferase. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Yeast growth in raffinose results in resistance to acetic-acid induced programmed cell death mostly due to the activation of the mitochondrial retrograde pathway. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Substrate-HeNe laser interaction: a contribution to the knowledge of the stimulation mechanism. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Fumarate permeation in normal and acidotic rat kidney mitochondria: fumarate/malate and fumarate/aspartate translocators. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• AZT side effect on mitochondria does not depend on either inhibition of electron flow or mitochondrial uncoupling (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Shift in pH-rate profile and enhanced discrimination between dicarboxylic and aromatic substrates in mitochondrial aspartate aminotransferase Y70H. (Articolo in rivista) (Prodotto della ricerca)
• Ultrastructural zonal heterogeneity of hepatocytes and mitochondria within the hepatic acinus during liver regeneration after partial hepatectomy. (Articolo in rivista) (Prodotto della ricerca)
• Cytochrome c Is Released in a Reactive Oxygen Species-Dependent Manner and Is Degraded via Caspase-Like Proteases in Tobacco Bright-Yellow 2 Cells en Route to Heat Shock-Induced Cell Death. (Articolo in rivista) (Prodotto della ricerca)
• Plant uncoupling protein in mitochondria from aged-dehydrated slices of Jerusalem artichoke tubers becomes sensitive to superoxide and to hydrogen peroxide without increase in protein level. (Articolo in rivista) (Prodotto della ricerca)
• Down-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation. (Articolo in rivista) (Prodotto della ricerca)
• Production of reactive oxygen species, alteration of cytosolic ascorbate peroxidase, and impairment of mitochondrial metabolism are early events in heat shock-induced programmed cell death in tobacco Bright-Yellow 2 cells. (Articolo in rivista) (Prodotto della ricerca)
• Thyroid hormone treatment of hypothyroid rats restores the regenerative capacity and the mitochondrial membrane permeability properties of the liver after partial hepatectomy. (Articolo in rivista) (Prodotto della ricerca)
• Molecular screening of genetic defects with RNA-SSCP analysis: the PKU and cystinuria model (Articolo in rivista) (Prodotto della ricerca)
• Over-expression in Escherichia coli and characterization of two recombinant isoforms of human FAD synthetase. (Articolo in rivista) (Prodotto della ricerca)
• Use of protease sensitivity to probe the conformations of newly synthesised mutant forms of mitochondrial aspartate aminotransferase. (Articolo in rivista) (Prodotto della ricerca)
• The expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2. (Articolo in rivista) (Prodotto della ricerca)
• Carrier mediated GABA translocation into rat brain mitochondria. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial dysfunction as a central actor in intellectual disability-related diseases: An overview of Down syndrome, autism, Fragile X and Rett syndrome (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Oxaloacetate uptake into rat brain mitochondria and reconstruction of the malate/oxaloacetate shuttle. (Articolo in rivista) (Prodotto della ricerca)
• Clusterin Expression in Endometrial Cancer (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• The role of metal ions in the uptake of aspartate aminotransferase and malate dehydrogenase into isolated rat liver mitochondria in vitro (Articolo in rivista) (Prodotto della ricerca)
• Upregulation of Skp2 after Prostate Cancer Cell Adhesion to Extracellular Matrix Proteins (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Photosensitivity of DNA replication and respiration to haematoporphyrin derivative (photofrin II) in mammalian CV-1 cells. (Articolo in rivista) (Prodotto della ricerca)
• Alzheimer's proteins, oxidative stress, and mitochondrial dysfunction interplay in a neuronal model of Alzheimer's disease (Articolo in rivista) (Prodotto della ricerca)
• A DOUBLE ALTERATION OF THE ADP/ATP TRANSLOCATOR, WHICH DEPENDS ON BOTH ROS PRODUCTION AND CASPASES, TRIGGERS THE MITOCHONDRIAL PERMEABILITY TRANSITION, DISPENSABLE DURING CEREBELLAR GRANULE CELL APOPTOSIS (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• The occurrence of riboflavin kinase and FAD synthetase ensures FAD synthesis in tobacco mitochondria and maintenance of cellular redox status (Articolo in rivista) (Prodotto della ricerca)
• Stress-related mitochondrial components and mitochondrial genome as targets of anticancer therapy (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Yeast as a tool to study mitochondrial retrograde pathway en route to cell stress response. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Genistein and daidzein prevent low potassium-dependent apoptosis of cerebellar granule cells (Articolo in rivista) (Prodotto della ricerca)
• Deficit of complex I activity in human skin fibroblasts with chromosome 21 trisomy and overproduction of reactive oxygen species by mitochondria: involvement of the cAMP/PKA signalling pathway (Articolo in rivista) (Prodotto della ricerca)
• Human fad synthase (isoform 2): a component of the machinery that delivers fad to apo-flavoproteins. (Articolo in rivista) (Prodotto della ricerca)
• Achievements and perspectives in yeast acetic acid-induced programmed cell death pathways (Articolo in rivista) (Prodotto della ricerca)
• Active-site Arg --> Lys substitutions alter reaction and substrate specificity of aspartate aminotransferase. (Articolo in rivista) (Prodotto della ricerca)
• L-lactate metabolism can occur in normal and cancer prostate cells via the novel mitochondrial L-lactate dehydrogenase (Articolo in rivista) (Prodotto della ricerca)
• Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cells (Articolo in rivista) (Prodotto della ricerca)
• Cytochrome c Trp65Ser substitution results in inhibition of acetic acid-induced programmed cell death in Saccharomyces cerevisiae (Articolo in rivista) (Prodotto della ricerca)
• Estrogen receptor beta activation impairs mitochondrial oxidative metabolism and affects malignant mesothelioma cell growth in vitro and in vivo. (Articolo in rivista) (Prodotto della ricerca)
• Yeast acetic acid-induced programmed cell death can occur without cytochrome c release which requires metacaspase YCA1 (Articolo in rivista) (Prodotto della ricerca)
• L-lactate generates hydrogen peroxide in purified rat liver mitochondria due to the putative L-lactate oxidase localized in the intermembrane space. (Articolo in rivista) (Prodotto della ricerca)
• Hydrogen peroxide and superoxide anion production during acetic acid-induced yeast programmed cell death. (Articolo in rivista) (Prodotto della ricerca)
• Cumulative effects of mutations in newly synthesised mitochondrial aspartate aminotransferase on uptake into mitochondria. (Articolo in rivista) (Prodotto della ricerca)
• A transient proteasome activation is needed for acetic acid-induced programmed cell death to occur in Saccharomyces cerevisiae. (Articolo in rivista) (Prodotto della ricerca)
• Over-expression in Escherichia coli, purification and characterization of isoform 2 of human FAD synthetase. (Articolo in rivista) (Prodotto della ricerca)
• Succinate dehydrogenase flavoprotein subunit expression in Saccharomyces cerevisiae- involvement of the mitochondrial FAD transporter, Flx1p. (Articolo in rivista) (Prodotto della ricerca)
• Yeast as a tool to study signalling pathways in mitochondrial stress response and cytoprotection (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The IGF-I axis in thyroid carcinoma (Articolo in rivista) (Prodotto della ricerca)
• Teaching the role of mitochondrial transport in energy metabolism (Articolo in rivista) (Prodotto della ricerca)
• Transport and metabolism of L-lactate occur in mitochondria from cerebellar granule cells and are modified in cells undergoing low potassium dependent apoptosis (Articolo in rivista) (Prodotto della ricerca)
• Phosphoenolpyruvate metabolism in Jerusalem artichoke mitochondria (Articolo in rivista) (Prodotto della ricerca)
• Partial reconstruction of in vitro gluconeogenesis arising from mitochondrial l-lactate uptake/metabolism and oxaloacetate export via novel L-lactate translocators. (Articolo in rivista) (Prodotto della ricerca)
• Over-expression in Escherichia coli, functional characterization and refolding of rat dimethylglycine dehydrogenase. (Articolo in rivista) (Prodotto della ricerca)
• Photomodulation of cellular and subcellular activities by He-Ne laser (Articolo in rivista) (Prodotto della ricerca)
• Upregulation of Skp2 after prostate cancer cell adhesion to basement membranes results in BRCA2 degradation and cell proliferation (Articolo in rivista) (Prodotto della ricerca)
• The purified recombinant precursor of rat mitochondrial dimethylglycine dehydrogenase binds FAD via an autocatalytic reaction. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial DNA depletion in prostate epithelial cells promotes anoikisis resistance and invasion through activation of PI3K/Akt2 (Articolo in rivista) (Prodotto della ricerca)
• Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme. (Articolo in rivista) (Prodotto della ricerca)
• Different sources of reactive oxygen species contribute to low-potassium induced apoptosis in cerebellar granule cells (Articolo in rivista) (Prodotto della ricerca)
• Identification of a caspase-derived n-terminal tau fragment in cellular and animal alzheimer disease models (Articolo in rivista) (Prodotto della ricerca)
• Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Import of mutant forms of mitochondrial aspartate aminotransferase into isolated mitochondria (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The N-terminal region of mature mitochondrial aspartate aminotransferase can direct cytosolic dihydrofolate reductase into mitochondria in vitro. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pro-death and pro-life cellular strategies in yeast: the role of mitochondria (Comunicazione a convegno) (Prodotto della ricerca)
• Genetic history of phenylketonuria mutations in Italy. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Novel missense mutation in the phenylalanine hydroxylase gene leading to complete loss of enzymatic activity. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Yeast programmed cell death pathway: a new experimental platform for biomedical and agri-food sciences (Abstract/Poster in convegno) (Prodotto della ricerca)
• Certain N-terminal peptides inhibit uptake of mature aspartate aminotransferase by isolated mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Is there a pyruvate kinase in pig liver mitochondria? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• How Saccharomyces cerevisiae cells die as a function of time in response to acetic acid: the role of superoxide dismutase, catalane, released cytochrome c, proteasome and metacaspase. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• The yeast Saccharomyces cerevisiae is a model to elucidate the mechanism of programmed cell death in eukaryotes. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• The caspase dependent alteration of the ADP/ATP translocator triggers the mitochondrial permeability transition in apoptosis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Nitric oxide production, NOS activity and nNOS protein expression in the early phase of cerebellar granule cells apoptosis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• ADP/ATP carrier/PTP component metamorphosis in cerebellar granule cells undergoing apoptosis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Antioxidant role of hydroxytyrosol on oxidative stress in cadmium-intoxicated rats: Different effect in spleen and testes (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Impairment of F1F0-ATPase, adenine nucleotide translocator and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with chromosome 21 trisomy (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Early release and subsequent caspase-mediated degradation of cytochrome c in apoptotic cerebellar granule cells. (Articolo in rivista) (Prodotto della ricerca)
• Yeast programmed cell death: integration of cell adaptation and death pathways through mitochondrial stress response pathways (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Neuronal apoptosis in rats is accompanied by rapid impairment of cellular respiration and is prevented by scavengers of reactive oxygen species. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial energy metabolism in the left ventricular tissue of spontaneously hypertensive rats: abnormalities in both adeninenucleotide and phosphate translocators and enzyme adenylate-kinase and creatine-phosphokinase activities (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Glutamate neurotoxicity in rat cerebellar granule cells involves cytochrome c release from mitochondria and mitochondrial shuttle impairment. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Abnormal transport of inorganic phosphate in left ventricular mitochondria from spontaneously hypertensive rats. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Glycolytic enzyme upregulation and numbness of mitochondrial activity characterize the early phase of apoptosis in cerebellar granule cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Morphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink-parkin pathway (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Extracellular ADP prevents neuronal apoptosis via activation of cell antioxidant enzymes and protection of mitochondrial ANT-1 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Molecular mechanisms of Saccharomyces cerevisiae stress adaptation and programmed cell death in response to acetic acid. (Articolo in rivista) (Prodotto della ricerca)
• Thioredoxin/thioredoxin reductase system involvement in cerebellar granule cell apoptosis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Light-biological system interaction: mitochondria and isolated enzymes as light targets (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Changes in enzyme levels in hypertensive heart tissue. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• ROLE OF MITOCHONDRIAL DYSFUNCTIONS IN DOWN SYNDROME PATHOGENESIS: NEW MOLECULAR TARGETS AND THERAPEUTIC STRATEGIES (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Molecular targets and role of mitochondria dysfunction in Down syndrome pathogenesis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• A novel property of adenine nucleotides: sensitivity to helium-neon laser in mitochondrial reactions (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The mitochondria in cerebellar granule cells (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• ATP at a Crossroads: Cell Life or Death? (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• The role of mitochondrial transport in energy metabolism. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Changes in mitochondrial function and ultrastructure during rat liver regeneration (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Jerusalem artichoke mitochondria can export reducing equivalents in the form of malate as a result of D-lactate uptake and metabolism. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Transport and metabolism of D-lactate in Jerusalem artichoke mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Hepatocyte 'priming' and increase in transforming growth factor-beta1 mRNA expression are delayed in hypothyroid versus euthyroid rats during liver regeneration. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Inhibition of phosphate transport in rat heart mitochondria by 3'-azido-3'-deoxythymidine due to stimulation of superoxide anion mitochondrial production (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Yeast Stress, Aging, and Death (Articolo in rivista) (Prodotto della ricerca)
• Proteasome inhibitors prevent cytochrome c release during apoptosis but not in excitotoxic death of cerebellar granule neurons (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Beta1 integrin cytoplasmic variants differentially regulate expression of the antiangiogenic extracellular matrix protein thrombospondin 1. (Articolo in rivista) (Prodotto della ricerca)
• Native Myelin Proteins and Myelin Assembly in the Central Nervous System. (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• CNS Myelin Proteins in Lipid Bound Native Form as Tools for Study, Detection and Treatment of Multiple Sclerosis. (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Mitochondrial DNA depletion reduces PARP-1 levels and promotes progression of the neoplastic phenotype in prostate carcinoma (Articolo in rivista) (Prodotto della ricerca)
• Cytochrome c is released from coupled mitochondria of yeast en route to acetic acid-induced programmed cell death and can work as an electron donor and a ROS scavenger. (Articolo in rivista) (Prodotto della ricerca)
• The rate of ATP export in the extramitochondrial phase via the adenine nucleotide translocator changes in aging in mitochondria isolated from heart left ventricle of either normotensive or spontaneously hypertensive rats (Articolo in rivista) (Prodotto della ricerca)
• Interaction between NH2-tau fragment and A_beta in AD mitochondria contributes to the synaptic deterioration (Articolo in rivista) (Prodotto della ricerca)
• Skp2 overexpression is associated with loss of BRCA2 protein in human prostate cancer (Articolo in rivista) (Prodotto della ricerca)
• Silencing of BRCA2 decreases anoikis and its heterologous expression sensitizes yeast cells to acetic acid-induced programmed cell death. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pyruvate kinase in pig liver mitochondria (Articolo in rivista) (Prodotto della ricerca)
• Knock-out of metacaspase and/or cytochrome c results in the activation of a ROS-independent acetic acid-induced programmed cell death pathway in yeast (Articolo in rivista) (Prodotto della ricerca)
• Apoptosis and cytochrome c release in cerebellar granule cells. (Articolo in rivista) (Prodotto della ricerca)
• Two separate pathways for d-lactate oxidation by Saccharomyces cerevisiae mitochondria which differ in energy production and carrier involvement. (Articolo in rivista) (Prodotto della ricerca)
• T Lymphocytes Possess Receptors for Brain Myelin Small Protein. (Articolo in rivista) (Prodotto della ricerca)
• In vitro Binding of Myelin Basic Protein to Human Peripheral Blood T Lymphocytes from Healthy Donors. A Comparison between Lipid Bound and Lipid Free Protein. (Articolo in rivista) (Prodotto della ricerca)
• A peptide containing residues 26-44 of tau protein impairs mithocondrial oxidative phosphorylation acting ... (Articolo in rivista) (Prodotto della ricerca)
• Estimation of Protein Secondary Structure from Circular Dichroism Spectra: a Critical Examination of the Contin Program. (Articolo in rivista) (Prodotto della ricerca)
• Molecular and functional characteristics of erbB2 in normal and cancer breast cells. (Articolo in rivista) (Prodotto della ricerca)
• Biogenesi dei mitocondri e patologie mitocondriali. (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Perspectives of protein engineering in the study of molecular basis of human inherited diseases. (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Catalase T and Cu,Zn-superoxide dismutase in the acetic acid-induced programmed cell death in Saccharomyces cerevisiae. (Articolo in rivista) (Prodotto della ricerca)
• A New Protein of the Brain Myelin: Isolation and Chemical Characterization. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The Structural and functional features of the mitochondrial DNA. (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• YCA1 participates in the acetic acid induced yeast programmed cell death also in a manner unrelated to its caspase-like activity. (Articolo in rivista) (Prodotto della ricerca)
• Inhibition of E Rosette Formation and Bacterial Adherence to Human Peripheral Blood Lymphocytes by the Phosphatidylserine Binding Protein of Brain Myelin. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• In the early phase of programmed cell death in Tobacco Bright Yellow 2 cells the mitochondrial adenine nucleotide translocator, adenylate kinase and nucleoside diphosphate kinase are impaired in a reactive oxygen species-dependent manner. (Articolo in rivista) (Prodotto della ricerca)
• An efficient method for PCR analysis of mitochondrial DNA from paraffin-embedded archival heart tissue. (Articolo in rivista) (Prodotto della ricerca)
• Spontaneous Adhesiveness of Lipid Free Myelin Basic Protein to Immune Cells as Detected by a Double Labelling Technique. (Articolo in rivista) (Prodotto della ricerca)
• Detection of microsatellites by ethidium bromide staining. The analysis of the STR system in the human phenylalanine hydroxylase gene. (Articolo in rivista) (Prodotto della ricerca)
• Characterization of mitochondrial DNA in primary cardiomyopathies. (Articolo in rivista) (Prodotto della ricerca)
• Specificity of zinc binding to myelin basic protein. (Articolo in rivista) (Prodotto della ricerca)
• Cytochrome c is released from mitochondria in a reactive oxygen species (ROS)-dependent fashion and can operate as a ROS scavenger and as a respiratory substrate in cerebellar neurons undergoing excitotoxic death. (Articolo in rivista) (Prodotto della ricerca)
• Characterization of CAH alleles with non-radioactive DNA single strand conformation polymorphism analysis of the CYP21 gene. (Articolo in rivista) (Prodotto della ricerca)
• A Regulatory Role of NAD Redox Status on Flavin Cofactor Homeostasis in S. cerevisiae Mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• On the role of mitochondria in cell life and death decisions in a yeast model (Comunicazione a convegno) (Prodotto della ricerca)
• Detection of reactive oxygen species in primary cultures of cerebellar granule cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Bioenergetica e ipertensione genetica: quale ruolo per i mitocondri nell'ipertrofia ventricolare sinistra? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• ATP synthesis and export in heart left ventricle mitochondria from spontaneously hypertensive rat. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Glucose-6-phosphate tips the balance in modulating apoptosis in cerebellar granule cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• FAD Synthesis and Degradation in the Nucleus Create a Local Flavin Cofactor Pool (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Hematoporphyrin derivative (Photofrin II) photosensitization of isolated mitochondria: impairment of anion translocation. (Articolo in rivista) (Prodotto della ricerca)
• Oxaloacetate permeation in rat kidney mitochondria: pyruvate/oxaloacetate and malate/oxaloacetate translocators. (Articolo in rivista) (Prodotto della ricerca)
• Inhibition of the uptake of mitochondrial aspartate aminotransferase by cytoplasmically synthesized protein (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial retrograde signaling involvement in acetic acid-induced programmed cell death in yeast Saccharomyces cerevisiae (Comunicazione a convegno) (Prodotto della ricerca)
• The role of mitochondria in yeast programmed cell death (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The N-acetylcysteine-insensitive acetic acid-induced yeast programmed cell death occurs without macroautophagy (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Yeast between life and death: a summary of the Ninth International Meeting on Yeast Apoptosis in Rome, Italy, 17-20 September 2012. (Articolo in rivista) (Prodotto della ricerca)
• Glutamate Neurotoxicity in Rat Cerebellar Granule Cells: a major role for xanthine oxidase in oxygen radical formation (Articolo in rivista) (Prodotto della ricerca)
• Photosensitization of isolated mitochondria by hematoporphyrin derivative (Photofrin): effects on bioenergetics. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Proline transport in rat kidney mitochondria (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pyruvate/malate antiporter in rat liver mitochondria (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial stress response and cell adaptation in Saccharomyces cerevisiae (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Corrigendum to AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons, [Neurobioly of Disease (2014) 62, 489-507] DOI: 10.1016/j.nbd.2013.10.018 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Caspase-dependent alteration of the ADP/ATP translocator triggers the mitochondrial permeability transition which is not required for the low-potassium-dependent apoptosis of cerebellar granule cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Molecular mechanisms of Saccharomyces cerevisiae stress adaptation and programmed cell death in response to acetic acid (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Nitric oxide has dual opposite roles during early and late phases of apoptosis in cerebellar granule neurons (Articolo in rivista) (Prodotto della ricerca)
• Biosynthesis of flavin cofactors in man: implications in health and disease. (Articolo in rivista) (Prodotto della ricerca)
• A transient proteasome activation is needed for acetic acid-induce programmed cell death to occur in Saccharomyces cerevisiae (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Beta1 integrins modulate cell adhesion by regulating insulin-like growth factor-II levels in the microenvironment. (Articolo in rivista) (Prodotto della ricerca)
• Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression. (Articolo in rivista) (Prodotto della ricerca)
• L-Lactate transport into rat heart mitochondria and reconstruction of the L-lactate/pyruvate shuttle (Articolo in rivista) (Prodotto della ricerca)
• Acid stress adaptation protects Saccharomyces cerevisiae from acetic acid-induced programmed cell death. (Articolo in rivista) (Prodotto della ricerca)
• Transcriptional regulation of beta(1) integrin expression in the physio/pathological states of human endometrial tissues (Articolo in rivista) (Prodotto della ricerca)
• An increase in the ATP levels occurs in cerebellar granule cells en route to apoptosis in which ATP derives from both oxidative phosphorylation and ... (Articolo in rivista) (Prodotto della ricerca)
• Differential proteome-metabolome profiling of YCA1-knock-out and wild type cells reveals novel metabolic pathways and cellular processes dependent on the yeast metacaspase. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondria as agents of disease and as drug targets (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• The antibiotics roseoflavin and 8-demethyl-8-amino-riboflavin from streptomyces davawensis are metabolized by human flavokinase and human fad synthetase. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Energy matters: mitochondrial proteomics for biomedicine. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Aromatase deficiency inhibits the permeability transition in mouse liver mitochondria (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial localization of human FAD synthetase isoform 1 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondria and L-lactate metabolism (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Validation of microarray data in human lymphoblasts shows a role of the ubiquitin-proteasome system and NF-kB in the pathogenesis of Down syndrome (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Riboflavin uptake and FAD synthesis in Saccharomyces cerevisiae mitochondria: involvement of the Flx1p carrier in FAD export. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by beta1 integrins. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The molecular basis of phenylketonuria in Latvia. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Molecular basis of cystic fibrosis in Lithuania. Incomplete CFTR mutation detection by PCR-based screening protocols (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Regulation of beta1C and beta1A integrin expression in prostate carcinoma cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Coordinated and reversible reduction of enzymes involved in terminal oxidative metabolism in skeletal muscle mitochondria from a riboflavin-responsive, multiple acyl-CoA dehydrogenase deficiency patient. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Loss of BRCA2 promotes prostate cancer cell invasion through up-regulation of matrix metalloproteinase-9. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pleiotropic effects of the yeast Sal1 and Aac2 carriers on mitochondrial function via an activity distinct from adenine nucleotide transport (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Constitutive activation of MAPK/ERK inhibits prostate cancer cell proliferation through upregulation of BRCA2. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Proteasome function is required for activation of programmed cell death in heat shocked tobacco Bright-Yellow 2 cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondria from the left heart ventricles of both normotensive and spontaneously hypertensive rats oxidize externally added NADH mostly via a novel malate/oxaloacetate shuttle as reconstructed in vitro. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's Disease. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The Role of Mitochondria in the Glucose Metabolism (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Genotypic hetereogeneity of the molecular basis of cystic fibrosis: the paradigm of lithuanian population genetic testing (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Molecular mechanisms of programmed cell death induced by acetic acid in Saccharomyces cerevisiae (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Mitochondrial impairment induces excitotoxic death in cerebellar granule cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Alternatively Spliced Variants of Beta1 Integrin Are Involved in the Modulation of Human Endometrial Transformation in Different Physiological/Pathological Conditions (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Mitochondrial respiratory chain Complexes I and IV are impaired by Beta-amyloid via direct interaction and through Complex I-dependent ROS production, respectively. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Regulation of mRNA and protein levels of beta 1 integrin variants in human prostate carcinoma (Articolo in rivista) (Prodotto della ricerca)

Codice

• SV.P15.003.001 (literal)

Anno di chiusura previsto

• 2017-01-01T00:00:00+01:00 (literal)

Istituto esecutore

• Istituto di biomembrane e bioenergetica (IBBE) (Istituto)

Primo anno di attività

• 2005-01-01T00:00:00+01:00 (literal)

Abstract

• Oggetto di studio della macrolinea sono i processi con cui macromolecole e componenti cellulari interagiscono all'interno della cellula e scambiano segnali fra le diverse cellule. Gli studi riguardano: 1) Aspetti fisiopatologici dell'omeostasi cellulare di interesse bioenergetico: a) Permeabilità mitocondriale e metabolismo energetico; b) Omeostasi dei cofattori flavinici; c) La comunicazione mitocondri-nucleo nella risposta cellulare allo stress. 2) Basi molecolari della morte cellulare: a) Bioenergetica mitocondriale nella morte cellulare; b) I determinanti cellulari nei processi culminanti con la morte cellulare. 3) Regolazione della proliferazione cellulare: a) Regolazione dell'espressione dei fattori di crescita e di adesione; b) Studio delle molecole coinvolte nella comunicazione intra- e inter-cellulare (literal)

Nome

• Interrelazione nucleo/citoplasma/mitocondri nell'omeostasi cellulare. (literal)

Descrizione

• Descrizione collaborazioni del modulo "Interrelazione nucleo/citoplasma/mitocondri nell'omeostasi cellulare. (SV.P15.003.001)" (Descrizione collaborazioni)
• Descrizione dello stato di avanzamento delle attività del modulo "Interrelazione nucleo/citoplasma/mitocondri nell'omeostasi cellulare. (SV.P15.003.001)" (Descrizione stato avanzamento attività)
• Descrizione del modulo "Interrelazione nucleo/citoplasma/mitocondri nell'omeostasi cellulare. (SV.P15.003.001)" (Descrizione modulo)

Modulo di

• Interrelazione nucleo/citoplasma/mitocondri nell'omeostasi cellulare. (SV.P15.003) (Commessa)

Gestore

• ANTONELLA BOBBA (Persona)

Incoming links:

Istituto esecutore di

• Istituto di biomembrane e bioenergetica (IBBE) (Istituto)

Gestore di

• ANTONELLA BOBBA (Persona)

Modulo

• Interrelazione nucleo/citoplasma/mitocondri nell'omeostasi cellulare. (SV.P15.003) (Commessa)

Descrizione di

• Descrizione collaborazioni del modulo "Interrelazione nucleo/citoplasma/mitocondri nell'omeostasi cellulare. (SV.P15.003.001)" (Descrizione collaborazioni)
• Descrizione del modulo "Interrelazione nucleo/citoplasma/mitocondri nell'omeostasi cellulare. (SV.P15.003.001)" (Descrizione modulo)
• Descrizione dello stato di avanzamento delle attività del modulo "Interrelazione nucleo/citoplasma/mitocondri nell'omeostasi cellulare. (SV.P15.003.001)" (Descrizione stato avanzamento attività)

Prodotto di

• Inhibition of phosphate transport in rat heart mitochondria by 3'-azido-3'-deoxythymidine due to stimulation of superoxide anion mitochondrial production (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Hepatocyte 'priming' and increase in transforming growth factor-beta1 mRNA expression are delayed in hypothyroid versus euthyroid rats during liver regeneration. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Jerusalem artichoke mitochondria can export reducing equivalents in the form of malate as a result of D-lactate uptake and metabolism. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Transport and metabolism of D-lactate in Jerusalem artichoke mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Molecular and functional characteristics of erbB2 in normal and cancer breast cells. (Articolo in rivista) (Prodotto della ricerca)
• Apoptosis and cytochrome c release in cerebellar granule cells. (Articolo in rivista) (Prodotto della ricerca)
• Two separate pathways for d-lactate oxidation by Saccharomyces cerevisiae mitochondria which differ in energy production and carrier involvement. (Articolo in rivista) (Prodotto della ricerca)
• In the early phase of programmed cell death in Tobacco Bright Yellow 2 cells the mitochondrial adenine nucleotide translocator, adenylate kinase and nucleoside diphosphate kinase are impaired in a reactive oxygen species-dependent manner. (Articolo in rivista) (Prodotto della ricerca)
• YCA1 participates in the acetic acid induced yeast programmed cell death also in a manner unrelated to its caspase-like activity. (Articolo in rivista) (Prodotto della ricerca)
• Catalase T and Cu,Zn-superoxide dismutase in the acetic acid-induced programmed cell death in Saccharomyces cerevisiae. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial DNA depletion reduces PARP-1 levels and promotes progression of the neoplastic phenotype in prostate carcinoma (Articolo in rivista) (Prodotto della ricerca)
• Cytochrome c is released from coupled mitochondria of yeast en route to acetic acid-induced programmed cell death and can work as an electron donor and a ROS scavenger. (Articolo in rivista) (Prodotto della ricerca)
• Beta1 integrin cytoplasmic variants differentially regulate expression of the antiangiogenic extracellular matrix protein thrombospondin 1. (Articolo in rivista) (Prodotto della ricerca)
• Pyruvate kinase in pig liver mitochondria (Articolo in rivista) (Prodotto della ricerca)
• Knock-out of metacaspase and/or cytochrome c results in the activation of a ROS-independent acetic acid-induced programmed cell death pathway in yeast (Articolo in rivista) (Prodotto della ricerca)
• The rate of ATP export in the extramitochondrial phase via the adenine nucleotide translocator changes in aging in mitochondria isolated from heart left ventricle of either normotensive or spontaneously hypertensive rats (Articolo in rivista) (Prodotto della ricerca)
• Interaction between NH2-tau fragment and A_beta in AD mitochondria contributes to the synaptic deterioration (Articolo in rivista) (Prodotto della ricerca)
• Skp2 overexpression is associated with loss of BRCA2 protein in human prostate cancer (Articolo in rivista) (Prodotto della ricerca)
• Down-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation. (Articolo in rivista) (Prodotto della ricerca)
• Ultrastructural zonal heterogeneity of hepatocytes and mitochondria within the hepatic acinus during liver regeneration after partial hepatectomy. (Articolo in rivista) (Prodotto della ricerca)
• Cytochrome c Is Released in a Reactive Oxygen Species-Dependent Manner and Is Degraded via Caspase-Like Proteases in Tobacco Bright-Yellow 2 Cells en Route to Heat Shock-Induced Cell Death. (Articolo in rivista) (Prodotto della ricerca)
• Plant uncoupling protein in mitochondria from aged-dehydrated slices of Jerusalem artichoke tubers becomes sensitive to superoxide and to hydrogen peroxide without increase in protein level. (Articolo in rivista) (Prodotto della ricerca)
• Over-expression in Escherichia coli and characterization of two recombinant isoforms of human FAD synthetase. (Articolo in rivista) (Prodotto della ricerca)
• Production of reactive oxygen species, alteration of cytosolic ascorbate peroxidase, and impairment of mitochondrial metabolism are early events in heat shock-induced programmed cell death in tobacco Bright-Yellow 2 cells. (Articolo in rivista) (Prodotto della ricerca)
• Thyroid hormone treatment of hypothyroid rats restores the regenerative capacity and the mitochondrial membrane permeability properties of the liver after partial hepatectomy. (Articolo in rivista) (Prodotto della ricerca)
• Partial reconstruction of in vitro gluconeogenesis arising from mitochondrial l-lactate uptake/metabolism and oxaloacetate export via novel L-lactate translocators. (Articolo in rivista) (Prodotto della ricerca)
• Over-expression in Escherichia coli, functional characterization and refolding of rat dimethylglycine dehydrogenase. (Articolo in rivista) (Prodotto della ricerca)
• Photomodulation of cellular and subcellular activities by He-Ne laser (Articolo in rivista) (Prodotto della ricerca)
• Upregulation of Skp2 after prostate cancer cell adhesion to basement membranes results in BRCA2 degradation and cell proliferation (Articolo in rivista) (Prodotto della ricerca)
• The IGF-I axis in thyroid carcinoma (Articolo in rivista) (Prodotto della ricerca)
• Teaching the role of mitochondrial transport in energy metabolism (Articolo in rivista) (Prodotto della ricerca)
• Transport and metabolism of L-lactate occur in mitochondria from cerebellar granule cells and are modified in cells undergoing low potassium dependent apoptosis (Articolo in rivista) (Prodotto della ricerca)
• Phosphoenolpyruvate metabolism in Jerusalem artichoke mitochondria (Articolo in rivista) (Prodotto della ricerca)
• Hydrogen peroxide and superoxide anion production during acetic acid-induced yeast programmed cell death. (Articolo in rivista) (Prodotto della ricerca)
• A transient proteasome activation is needed for acetic acid-induced programmed cell death to occur in Saccharomyces cerevisiae. (Articolo in rivista) (Prodotto della ricerca)
• Over-expression in Escherichia coli, purification and characterization of isoform 2 of human FAD synthetase. (Articolo in rivista) (Prodotto della ricerca)
• Succinate dehydrogenase flavoprotein subunit expression in Saccharomyces cerevisiae- involvement of the mitochondrial FAD transporter, Flx1p. (Articolo in rivista) (Prodotto della ricerca)
• Different sources of reactive oxygen species contribute to low-potassium induced apoptosis in cerebellar granule cells (Articolo in rivista) (Prodotto della ricerca)
• Identification of a caspase-derived n-terminal tau fragment in cellular and animal alzheimer disease models (Articolo in rivista) (Prodotto della ricerca)
• Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme. (Articolo in rivista) (Prodotto della ricerca)
• The purified recombinant precursor of rat mitochondrial dimethylglycine dehydrogenase binds FAD via an autocatalytic reaction. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial DNA depletion in prostate epithelial cells promotes anoikisis resistance and invasion through activation of PI3K/Akt2 (Articolo in rivista) (Prodotto della ricerca)
• Genistein and daidzein prevent low potassium-dependent apoptosis of cerebellar granule cells (Articolo in rivista) (Prodotto della ricerca)
• The occurrence of riboflavin kinase and FAD synthetase ensures FAD synthesis in tobacco mitochondria and maintenance of cellular redox status (Articolo in rivista) (Prodotto della ricerca)
• Yeast acetic acid-induced programmed cell death can occur without cytochrome c release which requires metacaspase YCA1 (Articolo in rivista) (Prodotto della ricerca)
• L-lactate generates hydrogen peroxide in purified rat liver mitochondria due to the putative L-lactate oxidase localized in the intermembrane space. (Articolo in rivista) (Prodotto della ricerca)
• L-lactate metabolism can occur in normal and cancer prostate cells via the novel mitochondrial L-lactate dehydrogenase (Articolo in rivista) (Prodotto della ricerca)
• Cytochrome c Trp65Ser substitution results in inhibition of acetic acid-induced programmed cell death in Saccharomyces cerevisiae (Articolo in rivista) (Prodotto della ricerca)
• Achievements and perspectives in yeast acetic acid-induced programmed cell death pathways (Articolo in rivista) (Prodotto della ricerca)
• Deficit of complex I activity in human skin fibroblasts with chromosome 21 trisomy and overproduction of reactive oxygen species by mitochondria: involvement of the cAMP/PKA signalling pathway (Articolo in rivista) (Prodotto della ricerca)
• Human fad synthase (isoform 2): a component of the machinery that delivers fad to apo-flavoproteins. (Articolo in rivista) (Prodotto della ricerca)
• L-Lactate transport into rat heart mitochondria and reconstruction of the L-lactate/pyruvate shuttle (Articolo in rivista) (Prodotto della ricerca)
• Acid stress adaptation protects Saccharomyces cerevisiae from acetic acid-induced programmed cell death. (Articolo in rivista) (Prodotto della ricerca)
• Transcriptional regulation of beta(1) integrin expression in the physio/pathological states of human endometrial tissues (Articolo in rivista) (Prodotto della ricerca)
• Beta1 integrins modulate cell adhesion by regulating insulin-like growth factor-II levels in the microenvironment. (Articolo in rivista) (Prodotto della ricerca)
• Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression. (Articolo in rivista) (Prodotto della ricerca)
• Coordinated and reversible reduction of enzymes involved in terminal oxidative metabolism in skeletal muscle mitochondria from a riboflavin-responsive, multiple acyl-CoA dehydrogenase deficiency patient. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Regulation of beta1C and beta1A integrin expression in prostate carcinoma cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Riboflavin uptake and FAD synthesis in Saccharomyces cerevisiae mitochondria: involvement of the Flx1p carrier in FAD export. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by beta1 integrins. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The molecular basis of phenylketonuria in Latvia. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Molecular basis of cystic fibrosis in Lithuania. Incomplete CFTR mutation detection by PCR-based screening protocols (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondria from the left heart ventricles of both normotensive and spontaneously hypertensive rats oxidize externally added NADH mostly via a novel malate/oxaloacetate shuttle as reconstructed in vitro. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Constitutive activation of MAPK/ERK inhibits prostate cancer cell proliferation through upregulation of BRCA2. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Proteasome function is required for activation of programmed cell death in heat shocked tobacco Bright-Yellow 2 cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Loss of BRCA2 promotes prostate cancer cell invasion through up-regulation of matrix metalloproteinase-9. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pleiotropic effects of the yeast Sal1 and Aac2 carriers on mitochondrial function via an activity distinct from adenine nucleotide transport (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondria and L-lactate metabolism (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Aromatase deficiency inhibits the permeability transition in mouse liver mitochondria (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial localization of human FAD synthetase isoform 1 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The antibiotics roseoflavin and 8-demethyl-8-amino-riboflavin from streptomyces davawensis are metabolized by human flavokinase and human fad synthetase. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Energy matters: mitochondrial proteomics for biomedicine. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Alzheimer's proteins, oxidative stress, and mitochondrial dysfunction interplay in a neuronal model of Alzheimer's disease (Articolo in rivista) (Prodotto della ricerca)
• The caspase dependent alteration of the ADP/ATP translocator triggers the mitochondrial permeability transition in apoptosis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Nitric oxide production, NOS activity and nNOS protein expression in the early phase of cerebellar granule cells apoptosis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• ADP/ATP carrier/PTP component metamorphosis in cerebellar granule cells undergoing apoptosis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• The yeast Saccharomyces cerevisiae is a model to elucidate the mechanism of programmed cell death in eukaryotes. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• How Saccharomyces cerevisiae cells die as a function of time in response to acetic acid: the role of superoxide dismutase, catalane, released cytochrome c, proteasome and metacaspase. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Lack of cytochrome c release en route to acetic acid-induced programmed cell death in caspase-like gene knockout yeast cells. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Programmed cell death in Saccharomyces cerevisiae. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• How Saccharomyces cerevisiae cells die as a function of time in response to acetic acid: relations among ROS, cytochrome c and caspase-like activity. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Clusterin Expression in Endometrial Cancer (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Upregulation of Skp2 after Prostate Cancer Cell Adhesion to Extracellular Matrix Proteins (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• A DOUBLE ALTERATION OF THE ADP/ATP TRANSLOCATOR, WHICH DEPENDS ON BOTH ROS PRODUCTION AND CASPASES, TRIGGERS THE MITOCHONDRIAL PERMEABILITY TRANSITION, DISPENSABLE DURING CEREBELLAR GRANULE CELL APOPTOSIS (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Changes in mitochondrial function and ultrastructure during rat liver regeneration (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• The mitochondria in cerebellar granule cells (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• ATP at a Crossroads: Cell Life or Death? (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Yeast programmed cell death triggered by aceti acid: ROS involvement and cytochrome c release. (Comunicazione a convegno) (Prodotto della ricerca)
• NITRIC OXIDE SYNTHASE UPREGULATION IN THE EARLY PHASE OF CEREBELLAR GRANULE CELLS APOPTOSIS (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• The molecular evolution of B6 enzymes: ribonuclease A as a model pyridoxal-5’-phosphate-dependent protoenzyme. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Il lievito Saccharomyces cerevisiae: un modello di eucariote unicellulare idoneo per studi di diversità genotipica e fenotipica. (Comunicazione a convegno) (Prodotto della ricerca)
• Genotypic hetereogeneity of the molecular basis of cystic fibrosis: the paradigm of lithuanian population genetic testing (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Molecular mechanisms of programmed cell death induced by acetic acid in Saccharomyces cerevisiae (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• The Role of Mitochondria in the Glucose Metabolism (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Mitochondria as agents of disease and as drug targets (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Impairment of F1F0-ATPase, adenine nucleotide translocator and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with chromosome 21 trisomy (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Proteasome inhibitors prevent cytochrome c release during apoptosis but not in excitotoxic death of cerebellar granule neurons (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Nitric oxide has dual opposite roles during early and late phases of apoptosis in cerebellar granule neurons (Articolo in rivista) (Prodotto della ricerca)
• A peptide containing residues 26-44 of tau protein impairs mithocondrial oxidative phosphorylation acting ... (Articolo in rivista) (Prodotto della ricerca)
• Alternatively Spliced Variants of Beta1 Integrin Are Involved in the Modulation of Human Endometrial Transformation in Different Physiological/Pathological Conditions (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Stress-related mitochondrial components and mitochondrial genome as targets of anticancer therapy (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Yeast as a tool to study signalling pathways in mitochondrial stress response and cytoprotection (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Yeast programmed cell death pathway: a new experimental platform for biomedical and agri-food sciences (Abstract/Poster in convegno) (Prodotto della ricerca)
• Pro-death and pro-life cellular strategies in yeast: the role of mitochondria (Comunicazione a convegno) (Prodotto della ricerca)
• Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Glutamate neurotoxicity, oxidative stress and mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Characterization of the CYP21 gene 5' flanking region in patients affected by 21-OH deficiency. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 21-hydroxylase deficiency in Italy: a distinct pattern of CYP21 mutations in a sample from southern Italy (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Myelin basic protein interaction with zinc and phosphate: fluorescence studies on the water-soluble form of the protein. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A new detergent to purify CNS myelin basic protein isoforms in lipid-bound form. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• On the Spontaneous Adherence of Myelin Basic Protein to Normal Lymphocytes. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Interaction of Cations with Lipid Free Myelin Basic Protein: A Spectroscopic Study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cytochrome c, released from cerebellar granule cells undergoing apoptosis or excytotoxic death, can generate protonmotive force and drive ATP synthesis in isolated mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The apoptosis/necrosis transition in cerebellar granule cells depends on the mutual relationship of the antioxidant and the proteolytic systems which regulate ROS production and cytochrome c release en route to death. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• An increase in the ATP levels occurs in cerebellar granule cells en route to apoptosis in which ATP derives from both oxidative phosphorylation and ... (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial impairment induces excitotoxic death in cerebellar granule cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Is there a pyruvate kinase in pig liver mitochondria? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The role of mitochondria in yeast programmed cell death (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The N-acetylcysteine-insensitive acetic acid-induced yeast programmed cell death occurs without macroautophagy (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial retrograde signaling involvement in acetic acid-induced programmed cell death in yeast Saccharomyces cerevisiae (Comunicazione a convegno) (Prodotto della ricerca)
• Yeast programmed cell death: integration of cell adaptation and death pathways through mitochondrial stress response pathways (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• ROLE OF MITOCHONDRIAL DYSFUNCTIONS IN DOWN SYNDROME PATHOGENESIS: NEW MOLECULAR TARGETS AND THERAPEUTIC STRATEGIES (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Molecular targets and role of mitochondria dysfunction in Down syndrome pathogenesis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Cytochrome c is released from mitochondria in a reactive oxygen species (ROS)-dependent fashion and can operate as a ROS scavenger and as a respiratory substrate in cerebellar neurons undergoing excitotoxic death. (Articolo in rivista) (Prodotto della ricerca)
• Characterization of CAH alleles with non-radioactive DNA single strand conformation polymorphism analysis of the CYP21 gene. (Articolo in rivista) (Prodotto della ricerca)
• Detection of microsatellites by ethidium bromide staining. The analysis of the STR system in the human phenylalanine hydroxylase gene. (Articolo in rivista) (Prodotto della ricerca)
• Characterization of mitochondrial DNA in primary cardiomyopathies. (Articolo in rivista) (Prodotto della ricerca)
• Specificity of zinc binding to myelin basic protein. (Articolo in rivista) (Prodotto della ricerca)
• An efficient method for PCR analysis of mitochondrial DNA from paraffin-embedded archival heart tissue. (Articolo in rivista) (Prodotto della ricerca)
• Spontaneous Adhesiveness of Lipid Free Myelin Basic Protein to Immune Cells as Detected by a Double Labelling Technique. (Articolo in rivista) (Prodotto della ricerca)
• Estimation of Protein Secondary Structure from Circular Dichroism Spectra: a Critical Examination of the Contin Program. (Articolo in rivista) (Prodotto della ricerca)
• T Lymphocytes Possess Receptors for Brain Myelin Small Protein. (Articolo in rivista) (Prodotto della ricerca)
• In vitro Binding of Myelin Basic Protein to Human Peripheral Blood T Lymphocytes from Healthy Donors. A Comparison between Lipid Bound and Lipid Free Protein. (Articolo in rivista) (Prodotto della ricerca)
• The Structural and functional features of the mitochondrial DNA. (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Caspase-dependent alteration of the ADP/ATP translocator triggers the mitochondrial permeability transition which is not required for the low-potassium-dependent apoptosis of cerebellar granule cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The role of mitochondrial transport in energy metabolism. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• IMPAIRMENT OF OXIDATIVE PHOSPHORYLATION APPARATUS AND OVERPRODUCTION OF RADICAL SPECIES BY MITOCHONDRIA IN DOWN SYNDROME (Abstract/Comunicazione in atti di convegno) (Prodotto della ricerca)
• Early release and subsequent caspase-mediated degradation of cytochrome c in apoptotic cerebellar granule cells. (Articolo in rivista) (Prodotto della ricerca)
• Inhibition of E Rosette Formation and Bacterial Adherence to Human Peripheral Blood Lymphocytes by the Phosphatidylserine Binding Protein of Brain Myelin. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A New Protein of the Brain Myelin: Isolation and Chemical Characterization. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Biogenesi dei mitocondri e patologie mitocondriali. (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Perspectives of protein engineering in the study of molecular basis of human inherited diseases. (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• Native Myelin Proteins and Myelin Assembly in the Central Nervous System. (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• CNS Myelin Proteins in Lipid Bound Native Form as Tools for Study, Detection and Treatment of Multiple Sclerosis. (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• The STR252-IVS10nt546-VNTR7 phenylalanine hydroxylase minihaplotype in five Mediterranean samples. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Phenylketonuria mutations and linked haplotypes in the Lithuanian population: origin of the most common R408W mutation. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Use of protease sensitivity to probe the conformations of newly synthesised mutant forms of mitochondrial aspartate aminotransferase. (Articolo in rivista) (Prodotto della ricerca)
• Molecular screening of genetic defects with RNA-SSCP analysis: the PKU and cystinuria model (Articolo in rivista) (Prodotto della ricerca)
• Shift in pH-rate profile and enhanced discrimination between dicarboxylic and aromatic substrates in mitochondrial aspartate aminotransferase Y70H. (Articolo in rivista) (Prodotto della ricerca)
• Validation of microarray data in human lymphoblasts shows a role of the ubiquitin-proteasome system and NF-kB in the pathogenesis of Down syndrome (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A sensitive method to assay the xanthine oxidase activity in primary cultures of cerebellar granule cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• AZT side effect on mitochondria does not depend on either inhibition of electron flow or mitochondrial uncoupling (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Fumarate permeation in normal and acidotic rat kidney mitochondria: fumarate/malate and fumarate/aspartate translocators. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Yeast growth in raffinose results in resistance to acetic-acid induced programmed cell death mostly due to the activation of the mitochondrial retrograde pathway. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Substrate-HeNe laser interaction: a contribution to the knowledge of the stimulation mechanism. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Glutamate stimulates 2-deoxyglucose uptake in rat cerebellar granule cells. (Articolo in rivista) (Prodotto della ricerca)
• Rapid uncoupling of oxidative phosphorylation accompanies glutamate toxicity in rat cerebellar granule cells (Articolo in rivista) (Prodotto della ricerca)
• Carrier-mediated transport controls hydroxyproline catabolism in heart mitochondria from spontaneously hypertensive rat (Articolo in rivista) (Prodotto della ricerca)
• The mechanism of proline/glutamate antiport in rat kidney mitochondria. Energy dependence and glutamate-carrier involvement (Articolo in rivista) (Prodotto della ricerca)
• IL MITOCONDRIO - Permeabilità e metabolismo (Curatela) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1501)
• Glutamine transport in normal and acidotic rat kidney mitochondria (Articolo in rivista) (Prodotto della ricerca)
• SPECTROSCOPIC STUDY OF HYDROXYPROLINE TRANSPORT IN RAT-KIDNEY MITOCHONDRIA (Articolo in rivista) (Prodotto della ricerca)
• Effects of rhodamine 123 in the dark and after irradiation on mitochondrial energy metabolism. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carrier thiols are targets of Photofrin II photosensitization of isolated rat liver mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• UPTAKE OF ASPARTATE-AMINOTRANSFERASE INTO MITOCHONDRIA INVITRO CAUSES EFFLUX OF MALATE-DEHYDROGENASE AND VICE VERSA (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Haematoporphyrin derivative (Photofrin II) photosensitization of isolated mitochondria: inhibition of ADP/ATP translocator. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Metabolite transport in rat kidney mitochondria: ornithine/phosphate translocator. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Increase in the ADP/ATP exchange in rat liver mitochondria irradiated in vitro by helium-neon laser. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Photosensitivity of DNA replication and respiration to haematoporphyrin derivative (photofrin II) in mammalian CV-1 cells. (Articolo in rivista) (Prodotto della ricerca)
• The role of metal ions in the uptake of aspartate aminotransferase and malate dehydrogenase into isolated rat liver mitochondria in vitro (Articolo in rivista) (Prodotto della ricerca)
• Carrier mediated GABA translocation into rat brain mitochondria. (Articolo in rivista) (Prodotto della ricerca)
• Oxaloacetate uptake into rat brain mitochondria and reconstruction of the malate/oxaloacetate shuttle. (Articolo in rivista) (Prodotto della ricerca)
• The mitochondrial genome encodes abundant small noncoding RNAs. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• On the role of mitochondria in cell life and death decisions in a yeast model (Comunicazione a convegno) (Prodotto della ricerca)
• FAD Synthesis and Degradation in the Nucleus Create a Local Flavin Cofactor Pool (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Yeast Stress, Aging, and Death (Articolo in rivista) (Prodotto della ricerca)
• Molecular mechanisms of Saccharomyces cerevisiae stress adaptation and programmed cell death in response to acetic acid. (Articolo in rivista) (Prodotto della ricerca)
• Active-site Arg --> Lys substitutions alter reaction and substrate specificity of aspartate aminotransferase. (Articolo in rivista) (Prodotto della ricerca)
• Cumulative effects of mutations in newly synthesised mitochondrial aspartate aminotransferase on uptake into mitochondria. (Articolo in rivista) (Prodotto della ricerca)
• Novel missense mutation in the phenylalanine hydroxylase gene leading to complete loss of enzymatic activity. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Genetic history of phenylketonuria mutations in Italy. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The N-terminal region of mature mitochondrial aspartate aminotransferase can direct cytosolic dihydrofolate reductase into mitochondria in vitro. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Import of mutant forms of mitochondrial aspartate aminotransferase into isolated mitochondria (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Certain N-terminal peptides inhibit uptake of mature aspartate aminotransferase by isolated mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Detection of reactive oxygen species in primary cultures of cerebellar granule cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• ATP synthesis and export in heart left ventricle mitochondria from spontaneously hypertensive rat. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Bioenergetica e ipertensione genetica: quale ruolo per i mitocondri nell'ipertrofia ventricolare sinistra? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Glutamate Neurotoxicity in Rat Cerebellar Granule Cells: a major role for xanthine oxidase in oxygen radical formation (Articolo in rivista) (Prodotto della ricerca)
• Yeast between life and death: a summary of the Ninth International Meeting on Yeast Apoptosis in Rome, Italy, 17-20 September 2012. (Articolo in rivista) (Prodotto della ricerca)
• Proline transport in rat kidney mitochondria (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pyruvate/malate antiporter in rat liver mitochondria (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Photosensitization of isolated mitochondria by hematoporphyrin derivative (Photofrin): effects on bioenergetics. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Hematoporphyrin derivative (Photofrin II) photosensitization of isolated mitochondria: impairment of anion translocation. (Articolo in rivista) (Prodotto della ricerca)
• Oxaloacetate permeation in rat kidney mitochondria: pyruvate/oxaloacetate and malate/oxaloacetate translocators. (Articolo in rivista) (Prodotto della ricerca)
• Inhibition of the uptake of mitochondrial aspartate aminotransferase by cytoplasmically synthesized protein (Articolo in rivista) (Prodotto della ricerca)
• Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cells (Articolo in rivista) (Prodotto della ricerca)
• Estrogen receptor beta activation impairs mitochondrial oxidative metabolism and affects malignant mesothelioma cell growth in vitro and in vivo. (Articolo in rivista) (Prodotto della ricerca)
• The expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2. (Articolo in rivista) (Prodotto della ricerca)
• Preservation of mitochondrial functional integrity in mitochondria isolated from small cryopreserved mouse brain areas (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Biosynthesis of flavin cofactors in man: implications in health and disease. (Articolo in rivista) (Prodotto della ricerca)
• Kinetic properties and thermal stabilities of mutant forms of mitochondrial aspartate aminotransferase. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Phenylalanine and tyrosine metabolism in PKU heterozygotes: influence of different PAH mutations. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Phenylketonuria in Italy: distinct distribution pattern of three mutations of the phenylalanine hydroxylase gene. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Characterization of phenylketonuria alleles in the Italian population. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The in vitro-synthesized precursor and mature mitochondrial aspartate aminotransferase share the same import pathway in isolated mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Expression of cDNAs encoding the precursor and the mature form of chicken mitochondrial aspartate aminotransferase in Escherichia coli. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Fumarate permeation in rat liver mitochondria: fumarate/malate and fumarate/phosphate translocators. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial respiratory chain Complexes I and IV are impaired by Beta-amyloid via direct interaction and through Complex I-dependent ROS production, respectively. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Glutamate neurotoxicity in rat cerebellar granule cells involves cytochrome c release from mitochondria and mitochondrial shuttle impairment. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Abnormal transport of inorganic phosphate in left ventricular mitochondria from spontaneously hypertensive rats. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Neuronal apoptosis in rats is accompanied by rapid impairment of cellular respiration and is prevented by scavengers of reactive oxygen species. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial energy metabolism in the left ventricular tissue of spontaneously hypertensive rats: abnormalities in both adeninenucleotide and phosphate translocators and enzyme adenylate-kinase and creatine-phosphokinase activities (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A novel property of adenine nucleotides: sensitivity to helium-neon laser in mitochondrial reactions (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Changes in enzyme levels in hypertensive heart tissue. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Light-biological system interaction: mitochondria and isolated enzymes as light targets (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Ornithine/phosphate antiport in rat kidney mitochondria. Some characteristics of the process. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anion transport in rat brain mitochondria: fumarate uptake via the dicarboxylate carrier. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial stress response and cell adaptation in Saccharomyces cerevisiae (Contributo in volume (capitolo o saggio)) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1201)
• A Regulatory Role of NAD Redox Status on Flavin Cofactor Homeostasis in S. cerevisiae Mitochondria. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Molecular mechanisms of Saccharomyces cerevisiae stress adaptation and programmed cell death in response to acetic acid (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Differential proteome-metabolome profiling of YCA1-knock-out and wild type cells reveals novel metabolic pathways and cellular processes dependent on the yeast metacaspase. (Articolo in rivista) (Prodotto della ricerca)
• NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's Disease. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Tissue-specific mtDNA abundance from exome data and its correlation with mitochondrial transcription, mass and respiratory activity. (Articolo in rivista) (Prodotto della ricerca)
• Mitochondrial retrograde signaling contributes to acetic acid-induced programmed cell death resistance in yeast (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Silencing of BRCA2 decreases anoikis and its heterologous expression sensitizes yeast cells to acetic acid-induced programmed cell death. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Morphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink-parkin pathway (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Extracellular ADP prevents neuronal apoptosis via activation of cell antioxidant enzymes and protection of mitochondrial ANT-1 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Thioredoxin/thioredoxin reductase system involvement in cerebellar granule cell apoptosis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Glycolytic enzyme upregulation and numbness of mitochondrial activity characterize the early phase of apoptosis in cerebellar granule cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Glucose-6-phosphate tips the balance in modulating apoptosis in cerebellar granule cells. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Yeast as a tool to study mitochondrial retrograde pathway en route to cell stress response. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A transient proteasome activation is needed for acetic acid-induce programmed cell death to occur in Saccharomyces cerevisiae (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Corrigendum to AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons, [Neurobioly of Disease (2014) 62, 489-507] DOI: 10.1016/j.nbd.2013.10.018 (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Dissecting the molecular mechanism by which NH2htau and Abeta1-42 peptides impair mitochondrial ANT-1 in Alzheimer disease (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial dysfunction in cancer chemoresistance (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Antioxidant role of hydroxytyrosol on oxidative stress in cadmium-intoxicated rats: Different effect in spleen and testes (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mitochondrial dysfunction as a central actor in intellectual disability-related diseases: An overview of Down syndrome, autism, Fragile X and Rett syndrome (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Regulation of mRNA and protein levels of beta 1 integrin variants in human prostate carcinoma (Articolo in rivista) (Prodotto della ricerca)
• http://www.cnr.it/ontology/cnr/individuo/prodotto/ID203245
• http://www.cnr.it/ontology/cnr/individuo/prodotto/ID203259