http://www.cnr.it/ontology/cnr/individuo/modulo/ID2517
Utilizzo della popolazionedell'Ogliastra per lo studio dei tratti fenotipici complessi legati all'invecchiamento (ME.P07.006.001)
- Type
- Label
- Utilizzo della popolazionedell'Ogliastra per lo studio dei tratti fenotipici complessi legati all'invecchiamento (ME.P07.006.001) (literal)
- Prodotto
- New gene functions in megakaryopoiesis and platelet formation. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common variants associated with plasma triglycerides and risk for coronary artery disease. (Articolo in rivista) (Prodotto della ricerca)
- Discovery and refinement of loci associated with lipid levels. (Articolo in rivista) (Prodotto della ricerca)
- Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. (Articolo in rivista) (Prodotto della ricerca)
- Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. (Articolo in rivista) (Prodotto della ricerca)
- Common variants at ten loci influence glycated hemoglobin levels via glycemic and non-glycemic pathways (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Common variants at ten loci modulate the QT interval duration in individuals of European ancestry: the QTSCD consortium (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- GWAS in Sardinians reveals novel loci for levels of inflammatory biomarkers. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Fine mapping of common and rare variants associated with low-densitylipoprotein cholesterol (LDL-C) via sequencing candidate loci following genome-wide scans. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Genome-wide association scan for bilirubin levels in a Sardinian population (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- Whole Genome Sequencing of 500 individuals in an Isolated Population (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Fine mapping of loci associated with low-density lipoprotein cholesterol (LDL-C) via candidate gene sequencing and large scale genotyping. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Harnessing hidden relatedness to incorporate missing heritability into genetic risk prediction (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Seventy-five genetic loci influencing the human red blood cell (Articolo in rivista) (Prodotto della ricerca)
- A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Longevity candidate genes and their association with personality traits in the elderly. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Personality Traits in Sardinia: Testing Founder Population Effects on Trait Means and Variances (Articolo in rivista) (Prodotto della ricerca)
- Genome-wide association scan for HDL cholesterol, LDL cholesterol and triglyceride levels in 9,000 individuals (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course. (Articolo in rivista) (Prodotto della ricerca)
- Genome-wide association scans in cohorts from Sardinia and Finland identify a locus for fasting glucose levels. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. (Articolo in rivista) (Prodotto della ricerca)
- Genotype Imputation (Articolo in rivista) (Prodotto della ricerca)
- A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. (Articolo in rivista) (Prodotto della ricerca)
- Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. (Articolo in rivista) (Prodotto della ricerca)
- Newly identified loci that influence lipid concentrations and risk of coronary artery disease (Articolo in rivista) (Prodotto della ricerca)
- Genome-wide association scan for five major dimensions of personality. (Articolo in rivista) (Prodotto della ricerca)
- The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Reproductive aging-associated common genetic variants and the risk of breast cancer. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- The GLUT9 Gene is Associated with Serum Uric Acid Levels in Sardinia and Chianti Cohorts. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common variants in the GDF5-BFZB region are associated with variation in human height. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- COMMON VARIANTS AT TEN LOCI INFLUENCE GLYCATED HEMOGLOBIN LEVELS VIA GLYCEMIC AND NON-GLYCEMIC PATHWAYS (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. (Articolo in rivista) (Prodotto della ricerca)
- An integrated map of genetic variation from 1,092 human genomes. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- hole Genome Sequencing of 1000 Individuals in an Isolated Population. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- Likelihood Based Deletion Analysis in a Sample of Sequenced Sardinian Individuals. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- A likelihood-based framework for variant calling and de novo mutation detection in families. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- An Empirical Approach for Inferring Polygenic Contributions in Genome-wide Case-Control studies. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Genetic Associations with the Variation in Aging from the SardiNIA/Progenia Project. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Heritability of cardiovascular and personality traits in 6,148 Sardinians. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- A genome wide association scan on the levels of inflammatory markers in Sardinia reveals associations with genes related with malaria resistance. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Heritability and genetic mapping of hundreds of immune-related quantitative traits measured in a large Sardinian cohort. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Common variants at ten loci modulate the QT interval duration in the QTSCD Study (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Large-scale transcriptome study in the Sardinian founder population. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Efficient computing of genotype calling for GWAS. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Scalable data management and computable framework for large scale longitudinal studies. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- A meta-analysis of thyroid-related traits reveals novel loci in the regulation of thyroid stimulating hormone and thyroxin circulating levels. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- A genome-wide analysis of Sardinian population structure (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Common variants near MC4R are associated with fat mass, weight and risk of obesity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- DNA polymorphisms at the BCL11A, HBS1L-MYB, and {beta}-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Using new tools to define the genetic underpinnings of risky traits associated with coronary artery disease: the SardiNIA study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Facets of personality linked to underweight and overweight. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association study identifies eight loci associated with blood pressure (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Variants of the Serotonin Transporter Gene and NEO-PI-R Neuroticism: No Association in the BLSA and SardiNIA Samples (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Six new loci associated with body mass index highlight a neuronal influence on body weight regulation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common variants at 30 loci contribute to polygenic dyslipidemia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta- Analysis of Three Genome-Wide Association Studies (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genomewide association study of PR interval (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Amelioration of Sardinian beta-0 thalassemia by genetic modifiers (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Associations of large artery structure and function with adiposity: Effects of age, gender, and hypertension. The SardiNIA Study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association analysis identifies multiple loci related to resting heart rate. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Neuroticism, depressive symptoms, and serum BDNF. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Sex-Specific Correlates of Walking Speed in a Wide Age-Ranged Population. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Cholesterol, triglycerides, and the five-factor model of personality. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genetic loci influencing kidney function and chronic kidney disease (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- 22. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association analysis identifies multiple loci related with resting heart rate (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Biological, clinical and population relevance of 95 loci for blood lipids (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- No Evidence for Genome-Wide Interactions on Plasma Fibrinogen by Smoking, Alcohol Consumption and Body Mass Index: Results from Meta-Analyses of 80,607 Subjects (Articolo in rivista) (Prodotto della ricerca)
- Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Age- and gender-specific awareness, treatment, and control of cardiovascular risk factors and subclinical vascular lesions in a founder population: the SardiNIA Study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- High neuroticism and low conscientiousness are associated with interleukin-6. (Articolo in rivista) (Prodotto della ricerca)
- Meta-analysis and imputation refines the association of 15q25 with smoking quantity. (Articolo in rivista) (Prodotto della ricerca)
- Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common variants at ten genomic loci influence hemoglobin A1C levels via glycemic and non-glycemic pathways. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-Wide Association Scan of Trait Depression (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association scan for height in 6,671 individuals from Finland and Sardinia. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Genetic variants regulating immune cell levels in health and disease. (Articolo in rivista) (Prodotto della ricerca)
- Progenia: primi risultati di un genome-wide scan con i gene-chip arrays Affymetrix 10K e 500K nella popolazione sarda (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci that Influence Uric Acid Concentrations (Abstract/Poster in convegno) (Prodotto della ricerca)
- Genome-wide Association Analysis Of 25,330 Individuals Identifies Multiple Loci Associated With Resting Heart Rate. (Comunicazione a convegno) (Prodotto della ricerca)
- Finemapping, Interaction Analyis and Rare Variant Patient Resequencing Results in novel QT interval loci identified by the QTSCD consortium (Comunicazione a convegno) (Prodotto della ricerca)
- GENOME-WIDE ASSOCIATION STUDY OF GLYCATED HEMOGLOBIN IDENTIFIES TEN COMMON VARIANTS IN GLYCEMIC AND NON-GLYCEMIC PATHWAYS (Abstract/Poster in convegno) (Prodotto della ricerca)
- A large genome-wide association study of glycated hemoglobin identifies ten common variants not mediated through BMI (Comunicazione a convegno) (Prodotto della ricerca)
- Fine mapping of common and rare variants associated with low-density lipoprotein cholesterol (LDL-C) via sequencing candidate loci following genome-wide scans (Comunicazione a convegno) (Prodotto della ricerca)
- Genome-wide association using jointly 10k and 500k Affymetrix chip in a Sardinia cohort (Comunicazione a convegno) (Prodotto della ricerca)
- BCL11A is associated with persistent HbF and ameliorates the ²-thalassemia phenotype. (Comunicazione a convegno) (Prodotto della ricerca)
- Genome-wide association scan for bilirubin levels in a Sardinian population (Comunicazione a convegno) (Prodotto della ricerca)
- Genome-wide association scan for serum TSH levels in 2375 Sardinian. (Comunicazione a convegno) (Prodotto della ricerca)
- COL4A1 Polymorphism Is Associated With Pulse Wave Velocity By Genome Wide Association Scan. (Abstract in rivista) (Prodotto della ricerca)
- Hundreds of variants clustered in genomic loci and biological pathways affect human height. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genetic variants influencing circulating lipid levels and risk of coronary artery disease. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Meta-analysis of genome-wide association studies for personality. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Draft sequencing of 1,000 genomes to study the genetics of quantitative traits: data production. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- BDNF Val66Met is Associated with Introversion and Interacts with 5-HTTLPR to Influence Neuroticism. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Software for Generating Linkage-disequilibrium Aware Genotype Calls From Next Generation Sequence Data (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- The central arterial burden of the metabolic syndrome is similar in men and women: the SardiNIA Study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- LocusZoom: Regional visualization of genome-wide association scan results. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- PROFILO GENETICO DELLA POPOLAZIONE SARDA ATTRAVERSO LO STUDIO DI 15 LOCI STR (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- COL4A1 Is Associated With Arterial Stiffness by Genome-Wide Association scan (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Variants in MTNR1B influence fasting glucose levels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genetics of serum BDNF: Meta-analysis of the Val66Met and genome-wide association study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Independent and additive effects of cytokine patterns and the metabolic syndrome on arterial aging in the SardiNIA Study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Personality traits prospectively predict verbal fluency in a lifespan sample. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Personality and metabolic syndrome. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Trait antagonism and the progression of arterial thickening: women with antagonistic traits have similar carotid arterial thickness as men. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common Genetic Variation in the 3-BCL11B Gene Desert Is Associated with Carotid-Femoral Pulse Wave Velocity and Excess Cardiovascular Disease Risk: The AortaGen Consortium. (Articolo in rivista) (Prodotto della ricerca)
- Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Fine mapping of five Loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Impulsivity-related traits are associated with higher white blood cell counts. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-Wide Association Scan Shows Genetic Variants in the FTO Gene Are Associated with Obesity-Related Traits (Articolo in rivista) (Prodotto della ricerca)
- Identification of ten loci associated with height highlights new biological pathways in human growth (Articolo in rivista) (Prodotto della ricerca)
- SHAVE - Shrinkage Estimator Measured for Multiple Visits Increases Power in GWAS of Quantitative Traits. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
- Post GWAS analysis of the BCL11A intronic region to define its role in regulating HbF levels. (Abstract/Poster in convegno) (Prodotto della ricerca)
- Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Managing Computing Resources in Large Sequencing Studies: Strategies and Lessons from Sequencing 2,120 Sardinian Genomes. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Heritability of the Variation in Aging in Two Longitudinal Family Cohort Studies: SardiNIA/Progenia Study and Framingham Heart Study. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- On the Sardinian ancestry of the Tyrolean Iceman. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- The contribution of sequencing based GWAS in explaining the missing heritability of quantitative traits. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Genome-wide association analyses identify 18 new loci associated with serum urate concentrations (Articolo in rivista) (Prodotto della ricerca)
- Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis (Articolo in rivista) (Prodotto della ricerca)
- FTO genotype is associated with phenotypic variability of body mass index. (Articolo in rivista) (Prodotto della ricerca)
- Sequencing-based GWAS on peripheral blood monocyte counts in the SardiNIA cohort (Abstract/Poster in convegno) (Prodotto della ricerca)
- Genetic landscape of the red blood cell. (Comunicazione a convegno) (Prodotto della ricerca)
- The association of thyroid peroxidase antibody risk loci with susceptibility to and phenotype of Graves' disease. (Articolo in rivista) (Prodotto della ricerca)
- Genotype calling and haplotyping in parent-offspring trios. (Articolo in rivista) (Prodotto della ricerca)
- Whole Genome Sequencing of 2100 Individuals in the founder Sardinian Population. (Comunicazione a convegno) (Prodotto della ricerca)
- Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Gene-age interactions in blood pressure regulation: A large-scale investigation with the CHARGE, global BPgen, and ICBP consortia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Population genomic analysis of ancient and modern genomes yields new insights into the genetic ancestry of the Tyrolean Iceman and the genetic structure of Europe. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Whole genome sequencing of 3,514 individuals from the isolated population of Sardinia (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
- Defining the role of common variation in the genomic and biological architecture of adult human height (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- First results of a genome-wide association using jointly 10k and 500k Affymetrix chips in a Sardinian cohort (Abstract/Poster in convegno) (Prodotto della ricerca)
- Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association scan for the five major dimensions of personality. (Abstract in rivista) (Prodotto della ricerca)
- Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association scan for serum bilirubin levels in a Sardinian cohort. (Abstract in rivista) (Prodotto della ricerca)
- The population structure and demographic history of Sardinia in relationship to neighboring populations. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Enhancing Sequencing Lab Workflows in the SardiNIA Project. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- The genetics of gene expression, splicing and transcriptional efficiency through Poly-A selection and ribosomal depletion RNA sequencing in humans. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Using low-pass whole genome sequencing to create a reference population for genome imputation in an isolated population: Examples from the SardiNIA study (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- Rational design of new candidate compounds for multiple sclerosis treatment based on analysis of biological targets identified through genome wide association studies in Sardinia. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
- Gli studi di associazione dell'intero genoma (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Codice
- Anno di chiusura previsto
- 2018-01-01T00:00:00+01:00 (literal)
- Istituto esecutore
- Primo anno di attività
- 2005-01-01T00:00:00+01:00 (literal)
- Abstract
- L'attività di ricerca inerente al suddetto modulo riguarda lo studio epidemiologico e l'identificazione dei fattori genetici di tratti associati all'invecchiamento, e di più generale interesse biomedico, nella popolazione Sarda, all'interno del Progetto ProgeNIA. Al fine di ridurre al minimo la variabilità genetica lo studio si focalizza sulla popolazione di quattro paesi dell'Ogliastra dove circa 7000 volontari prendono parte al progetto ProgeNIA. Ciascun volontario è stato caratterizzato per oltre 400 tratti quantitativi e genotipizzato con chip arrays contenti SNPs distribuiti a bassa, media ed alta densità sull'intero genoma.
Gli studi finora condotti hanno identificato numerose varianti geniche implicate nella regolazione della maggioranza dei tratti esaminati. Questi studi permetteranno di chiarire i meccanismi fisio-patologici alla base dei tratti analizzati e delle diverse condizioni/malattie, comuni nella popolazione, ad essi correlate. Lo studio della variazione di numerosi tratti appartenenti all'immunità cellulare (adattativa ed innata) e umorale in funzione dell'età permette di definire punti di intervento cruciali per le patologie immuno-mediate. (literal)
- Nome
- Utilizzo della popolazionedell'Ogliastra per lo studio dei tratti fenotipici complessi legati all'invecchiamento (literal)
- Descrizione
- Modulo di
- Gestore
Incoming links:
- Istituto esecutore di
- Modulo
- Descrizione di
- Gestore di
- Prodotto di
- Genome-Wide Association Scan Shows Genetic Variants in the FTO Gene Are Associated with Obesity-Related Traits (Articolo in rivista) (Prodotto della ricerca)
- Identification of ten loci associated with height highlights new biological pathways in human growth (Articolo in rivista) (Prodotto della ricerca)
- Sex-Specific Correlates of Walking Speed in a Wide Age-Ranged Population. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Cholesterol, triglycerides, and the five-factor model of personality. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genetic loci influencing kidney function and chronic kidney disease (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association analysis identifies multiple loci related with resting heart rate (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common variants at ten genomic loci influence hemoglobin A1C levels via glycemic and non-glycemic pathways. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-Wide Association Scan of Trait Depression (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Age- and gender-specific awareness, treatment, and control of cardiovascular risk factors and subclinical vascular lesions in a founder population: the SardiNIA Study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- High neuroticism and low conscientiousness are associated with interleukin-6. (Articolo in rivista) (Prodotto della ricerca)
- Meta-analysis and imputation refines the association of 15q25 with smoking quantity. (Articolo in rivista) (Prodotto della ricerca)
- Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Heritability of cardiovascular and personality traits in 6,148 Sardinians. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- The GLUT9 Gene is Associated with Serum Uric Acid Levels in Sardinia and Chianti Cohorts. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common variants in the GDF5-BFZB region are associated with variation in human height. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common variants near MC4R are associated with fat mass, weight and risk of obesity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- DNA polymorphisms at the BCL11A, HBS1L-MYB, and {beta}-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common variants at ten loci modulate the QT interval duration in the QTSCD Study (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta- Analysis of Three Genome-Wide Association Studies (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genomewide association study of PR interval (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Amelioration of Sardinian beta-0 thalassemia by genetic modifiers (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association study identifies eight loci associated with blood pressure (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Variants of the Serotonin Transporter Gene and NEO-PI-R Neuroticism: No Association in the BLSA and SardiNIA Samples (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Six new loci associated with body mass index highlight a neuronal influence on body weight regulation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common variants at 30 loci contribute to polygenic dyslipidemia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Using new tools to define the genetic underpinnings of risky traits associated with coronary artery disease: the SardiNIA study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Facets of personality linked to underweight and overweight. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Biological, clinical and population relevance of 95 loci for blood lipids (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association analysis identifies multiple loci related to resting heart rate. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Neuroticism, depressive symptoms, and serum BDNF. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- 22. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Associations of large artery structure and function with adiposity: Effects of age, gender, and hypertension. The SardiNIA Study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Longevity candidate genes and their association with personality traits in the elderly. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Personality Traits in Sardinia: Testing Founder Population Effects on Trait Means and Variances (Articolo in rivista) (Prodotto della ricerca)
- Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. (Articolo in rivista) (Prodotto della ricerca)
- Newly identified loci that influence lipid concentrations and risk of coronary artery disease (Articolo in rivista) (Prodotto della ricerca)
- Genome-wide association scan for five major dimensions of personality. (Articolo in rivista) (Prodotto della ricerca)
- Genotype Imputation (Articolo in rivista) (Prodotto della ricerca)
- Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- COL4A1 Is Associated With Arterial Stiffness by Genome-Wide Association scan (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Variants in MTNR1B influence fasting glucose levels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- BDNF Val66Met is Associated with Introversion and Interacts with 5-HTTLPR to Influence Neuroticism. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- The central arterial burden of the metabolic syndrome is similar in men and women: the SardiNIA Study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Hundreds of variants clustered in genomic loci and biological pathways affect human height. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genetic variants influencing circulating lipid levels and risk of coronary artery disease. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Meta-analysis of genome-wide association studies for personality. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Fine mapping of five Loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Common Genetic Variation in the 3-BCL11B Gene Desert Is Associated with Carotid-Femoral Pulse Wave Velocity and Excess Cardiovascular Disease Risk: The AortaGen Consortium. (Articolo in rivista) (Prodotto della ricerca)
- Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Personality and metabolic syndrome. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Trait antagonism and the progression of arterial thickening: women with antagonistic traits have similar carotid arterial thickness as men. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genetics of serum BDNF: Meta-analysis of the Val66Met and genome-wide association study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Independent and additive effects of cytokine patterns and the metabolic syndrome on arterial aging in the SardiNIA Study. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Personality traits prospectively predict verbal fluency in a lifespan sample. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Impulsivity-related traits are associated with higher white blood cell counts. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Gli studi di associazione dell'intero genoma (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- First results of a genome-wide association using jointly 10k and 500k Affymetrix chips in a Sardinian cohort (Abstract/Poster in convegno) (Prodotto della ricerca)
- Genome-wide association scan for serum bilirubin levels in a Sardinian cohort. (Abstract in rivista) (Prodotto della ricerca)
- Genome-wide association scan for the five major dimensions of personality. (Abstract in rivista) (Prodotto della ricerca)
- Genome-wide association scan for bilirubin levels in a Sardinian population (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- Common variants at ten loci influence glycated hemoglobin levels via glycemic and non-glycemic pathways (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Common variants at ten loci modulate the QT interval duration in individuals of European ancestry: the QTSCD consortium (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- GWAS in Sardinians reveals novel loci for levels of inflammatory biomarkers. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Fine mapping of common and rare variants associated with low-densitylipoprotein cholesterol (LDL-C) via sequencing candidate loci following genome-wide scans. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Fine mapping of loci associated with low-density lipoprotein cholesterol (LDL-C) via candidate gene sequencing and large scale genotyping. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Harnessing hidden relatedness to incorporate missing heritability into genetic risk prediction (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Whole Genome Sequencing of 500 individuals in an Isolated Population (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Genome-wide association scans in cohorts from Sardinia and Finland identify a locus for fasting glucose levels. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Genome-wide association scan for HDL cholesterol, LDL cholesterol and triglyceride levels in 9,000 individuals (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- COL4A1 Polymorphism Is Associated With Pulse Wave Velocity By Genome Wide Association Scan. (Abstract in rivista) (Prodotto della ricerca)
- BCL11A is associated with persistent HbF and ameliorates the ²-thalassemia phenotype. (Comunicazione a convegno) (Prodotto della ricerca)
- Genome-wide association using jointly 10k and 500k Affymetrix chip in a Sardinia cohort (Comunicazione a convegno) (Prodotto della ricerca)
- Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci that Influence Uric Acid Concentrations (Abstract/Poster in convegno) (Prodotto della ricerca)
- Genome-wide Association Analysis Of 25,330 Individuals Identifies Multiple Loci Associated With Resting Heart Rate. (Comunicazione a convegno) (Prodotto della ricerca)
- PROFILO GENETICO DELLA POPOLAZIONE SARDA ATTRAVERSO LO STUDIO DI 15 LOCI STR (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Software for Generating Linkage-disequilibrium Aware Genotype Calls From Next Generation Sequence Data (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- LocusZoom: Regional visualization of genome-wide association scan results. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Draft sequencing of 1,000 genomes to study the genetics of quantitative traits: data production. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Genome-wide association scan for height in 6,671 individuals from Finland and Sardinia. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Progenia: primi risultati di un genome-wide scan con i gene-chip arrays Affymetrix 10K e 500K nella popolazione sarda (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Genome-wide association scan for serum TSH levels in 2375 Sardinian. (Comunicazione a convegno) (Prodotto della ricerca)
- Genome-wide association scan for bilirubin levels in a Sardinian population (Comunicazione a convegno) (Prodotto della ricerca)
- Finemapping, Interaction Analyis and Rare Variant Patient Resequencing Results in novel QT interval loci identified by the QTSCD consortium (Comunicazione a convegno) (Prodotto della ricerca)
- GENOME-WIDE ASSOCIATION STUDY OF GLYCATED HEMOGLOBIN IDENTIFIES TEN COMMON VARIANTS IN GLYCEMIC AND NON-GLYCEMIC PATHWAYS (Abstract/Poster in convegno) (Prodotto della ricerca)
- A large genome-wide association study of glycated hemoglobin identifies ten common variants not mediated through BMI (Comunicazione a convegno) (Prodotto della ricerca)
- Fine mapping of common and rare variants associated with low-density lipoprotein cholesterol (LDL-C) via sequencing candidate loci following genome-wide scans (Comunicazione a convegno) (Prodotto della ricerca)
- COMMON VARIANTS AT TEN LOCI INFLUENCE GLYCATED HEMOGLOBIN LEVELS VIA GLYCEMIC AND NON-GLYCEMIC PATHWAYS (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- A meta-analysis of thyroid-related traits reveals novel loci in the regulation of thyroid stimulating hormone and thyroxin circulating levels. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- A genome-wide analysis of Sardinian population structure (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Large-scale transcriptome study in the Sardinian founder population. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Efficient computing of genotype calling for GWAS. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Scalable data management and computable framework for large scale longitudinal studies. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- An Empirical Approach for Inferring Polygenic Contributions in Genome-wide Case-Control studies. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Genetic Associations with the Variation in Aging from the SardiNIA/Progenia Project. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- A genome wide association scan on the levels of inflammatory markers in Sardinia reveals associations with genes related with malaria resistance. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- Heritability and genetic mapping of hundreds of immune-related quantitative traits measured in a large Sardinian cohort. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
- hole Genome Sequencing of 1000 Individuals in an Isolated Population. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- Likelihood Based Deletion Analysis in a Sample of Sequenced Sardinian Individuals. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- New gene functions in megakaryopoiesis and platelet formation. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Using low-pass whole genome sequencing to create a reference population for genome imputation in an isolated population: Examples from the SardiNIA study (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- Enhancing Sequencing Lab Workflows in the SardiNIA Project. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- The genetics of gene expression, splicing and transcriptional efficiency through Poly-A selection and ribosomal depletion RNA sequencing in humans. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Seventy-five genetic loci influencing the human red blood cell (Articolo in rivista) (Prodotto della ricerca)
- SHAVE - Shrinkage Estimator Measured for Multiple Visits Increases Power in GWAS of Quantitative Traits. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
- Post GWAS analysis of the BCL11A intronic region to define its role in regulating HbF levels. (Abstract/Poster in convegno) (Prodotto della ricerca)
- Managing Computing Resources in Large Sequencing Studies: Strategies and Lessons from Sequencing 2,120 Sardinian Genomes. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Heritability of the Variation in Aging in Two Longitudinal Family Cohort Studies: SardiNIA/Progenia Study and Framingham Heart Study. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- On the Sardinian ancestry of the Tyrolean Iceman. (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
- The contribution of sequencing based GWAS in explaining the missing heritability of quantitative traits. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. (Articolo in rivista) (Prodotto della ricerca)
- FTO genotype is associated with phenotypic variability of body mass index. (Articolo in rivista) (Prodotto della ricerca)
- Genotype calling and haplotyping in parent-offspring trios. (Articolo in rivista) (Prodotto della ricerca)
- Genome-wide association analyses identify 18 new loci associated with serum urate concentrations (Articolo in rivista) (Prodotto della ricerca)
- Genetic landscape of the red blood cell. (Comunicazione a convegno) (Prodotto della ricerca)
- Whole Genome Sequencing of 2100 Individuals in the founder Sardinian Population. (Comunicazione a convegno) (Prodotto della ricerca)
- A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Reproductive aging-associated common genetic variants and the risk of breast cancer. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- A likelihood-based framework for variant calling and de novo mutation detection in families. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- An integrated map of genetic variation from 1,092 human genomes. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genetic variants regulating immune cell levels in health and disease. (Articolo in rivista) (Prodotto della ricerca)
- Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. (Articolo in rivista) (Prodotto della ricerca)
- Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. (Articolo in rivista) (Prodotto della ricerca)
- Common variants associated with plasma triglycerides and risk for coronary artery disease. (Articolo in rivista) (Prodotto della ricerca)
- Discovery and refinement of loci associated with lipid levels. (Articolo in rivista) (Prodotto della ricerca)
- A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. (Articolo in rivista) (Prodotto della ricerca)
- Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course. (Articolo in rivista) (Prodotto della ricerca)
- Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. (Articolo in rivista) (Prodotto della ricerca)
- Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis (Articolo in rivista) (Prodotto della ricerca)
- The association of thyroid peroxidase antibody risk loci with susceptibility to and phenotype of Graves' disease. (Articolo in rivista) (Prodotto della ricerca)
- Sequencing-based GWAS on peripheral blood monocyte counts in the SardiNIA cohort (Abstract/Poster in convegno) (Prodotto della ricerca)
- The population structure and demographic history of Sardinia in relationship to neighboring populations. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
- Rational design of new candidate compounds for multiple sclerosis treatment based on analysis of biological targets identified through genome wide association studies in Sardinia. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
- Defining the role of common variation in the genomic and biological architecture of adult human height (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Gene-age interactions in blood pressure regulation: A large-scale investigation with the CHARGE, global BPgen, and ICBP consortia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- Population genomic analysis of ancient and modern genomes yields new insights into the genetic ancestry of the Tyrolean Iceman and the genetic structure of Europe. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
- No Evidence for Genome-Wide Interactions on Plasma Fibrinogen by Smoking, Alcohol Consumption and Body Mass Index: Results from Meta-Analyses of 80,607 Subjects (Articolo in rivista) (Prodotto della ricerca)
- Whole genome sequencing of 3,514 individuals from the isolated population of Sardinia (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
- Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)