Struttura, funzione e \"profiling\" di endocannabinoidi e ammidi bioattive di acidi grassi implicati nelle patologie umane (PM.P01.012.001)

Type

• Modulo (Classe)

Label

• Struttura, funzione e \"profiling\" di endocannabinoidi e ammidi bioattive di acidi grassi implicati nelle patologie umane (PM.P01.012.001) (literal)

Prodotto

• New analgesics synthetically derived from the paracetamol metabolite N-(4-hydroxyphenyl)-(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-enamide (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anandamide receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• New N-arachidonoylserotonin analogues with potential 'dual' mechanism of action against pain. (Articolo in rivista) (Prodotto della ricerca)
• Neuronal and glial alterations in the cerebellar cortex of maternally deprived rats: gender differences and modulatory effects of two inhibitors of endocannabinoid inactivation (Articolo in rivista) (Prodotto della ricerca)
• The anandamide membrane transporter inhibitor, VDM-11, modulates sleep and c-Fos expression in the rat brain. (Articolo in rivista) (Prodotto della ricerca)
• Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens (Articolo in rivista) (Prodotto della ricerca)
• The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoids: some like it fat (and sweet too). (Articolo in rivista) (Prodotto della ricerca)
• Synergistic effects of CB1, muscarinic and ´-opioid receptor agonists on intracellular Ca2+ mobilization in SH-SY5Y cells (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Potential use of cannabimimetics in the treatment of cancer (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• 2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents. (Articolo in rivista) (Prodotto della ricerca)
• Cannabinoid CB1 receptor elevation of intracellular calcium in neuroblastoma SH-SY5Y cells: interactions with muscarinic and delta-opioid receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides. (Articolo in rivista) (Prodotto della ricerca)
• Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase ? and ?/?-hydrolase domain 6 (Articolo in rivista) (Prodotto della ricerca)
• 1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor. (Articolo in rivista) (Prodotto della ricerca)
• The First Dual ChE/FAAH Inhibitors: New Perspectives for Alzheimer's Disease? (Articolo in rivista) (Prodotto della ricerca)
• Local administration of palmitoylethanolamide reduces chronic granuloma-associated pain in rats (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Effect of N-arachidonoylserotonin (AA-5-HT), a FAAH inhibitor with antagonistic activity at vanilloid TRPV1 receptor, in an animal model of acute inflammation. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Increased skin levels of the aliamide palmitoylethanolamide and endogenous fatty acid amides in dogs with atopic dermatitis. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Dual effect of the cannabinoid agonist HU-210 on the vanilloid VR1 receptor-induced intracellular calcium in cells expressing both CB1 and VR1 receptors (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• The effects of chronic exposure, withdrawal and voluntary consumption of alcohol on the endocannabinoid transmission in reward-related brain regions: bases for a pharmacological management of this system to reduce alcohol preference. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoid signaling system in a rat model of Multiple Sclerosis: beneficial effects of the endocannabinoid uptake inhibition. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Sex-dependent degenerative changes in the cerebellar cortex of maternally deprived rats. Modulatory effects of two inhibitors of endocannabinoids inactivation. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoids interfere with dendritic cells’life cycle by preventing the generation of mature DC (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• N-Oleoyldopamine: a novel endogenous lipid that activates VR1/CB1 receptors, produces hyperalgesia, and is recognized by the anandamide membrane transporter. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Homo-N-Arachidonoyl Dopamine mimics vanilloid receptor agonists in enhancing paired pulse depression of hippocampal population spikes. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Does acute lung inflammation lead to an increased synthesis of anandamide? A study in the mouse lung. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Entourage effects of N-palmitoyldopamine and N-stearoyldopamine on N-arachidonoyldopamine activity. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Alterations in endocnnabinoid levels accompanying parkinsonism and levodopa-induced dyskinesia in the MPTP-lesioned macaque (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Effects of modulation of vanilloid and cannabinoid signalling on locomotion in normal animals and in animal models of Parkinson’s disease. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Tissue distribution of 2-AG, PEA, ananadamide and Prostamides E2 and F2± in FAAH -/- and FAAH +/+ mice. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Synthesis and pharmacological evaluation of N-acylethanolamines oxygen homologated at the amide bond (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Enzymes for 2-AG biosynthesis and metabolism in cell lines, and their pharmacological inhibition. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• The taming of capsaicin. Synthesis and vanilloid antagonistic activity of isosteric and regioisomeric halononivamides and their products of halogen-carbon exchange (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Studies of the biosynthesis of N-Arachidonoyl Dopamine (NADA). (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Occurrence and biological role of the endocannabinoid system in Ciona Intestinalis (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Beneficial effects of inhibitors of the endocannabinoid transport in a rat model of Multiple Sclerosis: involvement of vanilloid TRPV1 receptors. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Evidence for a regulatory role of endocannabinoid system in the rat pineal gland activity. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Homologues and isomers of noladin ether, a putative novel endocannabinoid: interaction with rat cannabinoid CB(1) receptors. (Articolo in rivista) (Prodotto della ricerca)
• Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington’s disease. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Dual effect of inhibitors of endocannabinoid inactivation on memory retention in experimental models of Alzheimer’s disease (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• A structure-activity relationship study on N-arachidonoyl-amino acids as possible endogenous inhibitors of fatty acid amide hydrolase. (Articolo in rivista) (Prodotto della ricerca)
• Oxy-homologues of anandamide and related endolipids. Synthesis and biological evaluation. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Endocannabinoid and palmitoylethanolamide levels in eyes with diabetic retinopathy or macular degeneration (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. (Articolo in rivista) (Prodotto della ricerca)
• The endocannabinoid system in non-mammalian organisms: differences and commonalities with mammals (Abstract/Poster in convegno) (Prodotto della ricerca)
• Cannabinoid CB1 receptor activation inhibits MPTP-induced expression of S100B in glial cells thereby leading to survival of co-cultured neurons. Mechanism of action and involvement of endocannabinoids (Abstract/Poster in convegno) (Prodotto della ricerca)
• Novel selective inhibitors of anandamide re-uptake with anti-spastic activity in a mouse model of multiple sclerosis. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Peripheral up-regulation of the endocannabinoid system in obesity. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Impaired endocannabinoid levels in selected brain areas of transgenic R6/2 mice, and experimental model of Huntington’s disease. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Attenuation of allergic contact dermatitis through the endocannabinoid system. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways (Abstract/Poster in convegno) (Prodotto della ricerca)
• The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation (Articolo in rivista) (Prodotto della ricerca)
• TRPV1 channels control synaptic plasticity in the developing superior colliculus (Articolo in rivista) (Prodotto della ricerca)
• Protective role of palmitoylethanolamide in contact allergic dermatitis (Articolo in rivista) (Prodotto della ricerca)
• TRPV1 receptors in the central nervous system: potential for previously unforeseen therapeutic applications (Articolo in rivista) (Prodotto della ricerca)
• The endovanilloid/endocannabinoid system: a new potential target for osteoporosis therapy. (Articolo in rivista) (Prodotto della ricerca)
• The taming of capsaicin. Reversal of the vanilloid activity of N-acylvanillamines by aromatic iodination (Articolo in rivista) (Prodotto della ricerca)
• Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Palmitoylethanolamide counteracts reactive astrogliosis induced by beta-amyloid peptide (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Glutamate spillover drives endocannabinoid production and inhibits GABAergic transmission in the Substantia Nigra pars compacta (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid system mediates aerobic exercise-induced antinociception in rats (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Use of palmitoylethanolamide in the entrapment neuropathy of the median in the wrist. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Acute resistance exercise induces antinociception by activation of the endocannabinoid system in rats (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids: an appetite for fat. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effect of narrowband ultraviolet B treatment on endocannabinoid plasma levels in patients with psoriasis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Diacylglycerol lipase is not involved in depolarization-induced suppression of inhibition at unitary inhibitory connections in mouse hippocampus. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Possible Anandamide and Palmitoylethanolamide involvement in human stroke. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid receptors and endocannabinoids: role in neuroinflammatory and neurodegenerative disorders. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis and biological evaluation of new potential inhibitors of N-acylethanolamine hydrolyzing acid amidase. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• N-palmitoyl-ethanolamine: Biochemistry and new therapeutic opportunities. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 20. Maternal dietary fat determines metabolic profile and the magnitude of endocannabinoid inhibition of the stress response in neonatal rat offspring. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid CB1 receptor expression in relation to visceral adipose depots, endocannabinoid levels, microvascular damage, and the presence of the Cnr1 A3813G variant in humans (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: a critical revisitation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Rational design, synthesis, and pharmacological properties of new 1,8-naphthyridin-2(1H)-on-3-carboxamide derivatives as highly selective cannabinoid-2 receptor agonists (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Goldfish CB1 mRNA expression is affected by fasting and anandamide administration (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• CB1 antagonists for obesity--what lessons have we learned from rimonabant? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Rapid combinatorial access to a library of 1,5-disubstituted-3-indole-N-alkylacetamides as CB2 receptor ligands (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The biosynthesis of N-arachidonoyl dopamine (NADA), a putative endocannabinoid and endovanilloid, via conjugation of arachidonic acid with dopamine (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The prostamide analogue Bimatoprost inhibits adipogenic gene expression (Comunicazione a convegno) (Prodotto della ricerca)
• From endocannabinoid profiling to 'endocannabinoid therapeutics' (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• RETINOHYPOTHALAMIC PROJECTIONS TO LH ARE INVOLVED IN THE LIGHT-MEDIATED 2-AG ENDOCANNABINOID SYNTHESIS. CRITICAL ROLE OF OREXINERGIC AND ENDOCANNABINOID SYSTEMS IN LIGHT-ENTRAINABLE RHYTHMS (Comunicazione a convegno) (Prodotto della ricerca)
• Evaluation of oxidized linoleic acid metabolites as possible “endovanilloids” as compared to anandamide (Comunicazione a convegno) (Prodotto della ricerca)
• Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• MECHANISMS OF THE ANTI-CANCER EFFECTS OF CANNABIDIOL AND OTHER NON-PSYCHOTROPIC CANNABINOIDS ON HUMAN PROSTATE CARCINOMA (Comunicazione a convegno) (Prodotto della ricerca)
• Why is prostate cancer a legitimate target for cannabinoids? (Comunicazione a convegno) (Prodotto della ricerca)
• Characterization of the endocannabinoid system during zebrafish (Danio rerio) embryogenesis and possible drug screening applications (Comunicazione a convegno) (Prodotto della ricerca)
• ACTIVATION OF SPINAL TRPV1 OR CB1 RECEPTORS IN NEUROPATHIC RATS DEPENDS ON ANANDAMIDE CONCENTRATION (Comunicazione a convegno) (Prodotto della ricerca)
• Brain TRPV1: a depressing TR(i)P down memory lane? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• LIPID PROFILING OF HIGH-FAT-FED MICE AFTER DIETARY KRILL OIL SUPPLEMENTATION (Comunicazione a convegno) (Prodotto della ricerca)
• Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effect of chirality and lipophilicity in the functional activity of evodiamine and its analogues at TRPV1 channels. (Articolo in rivista) (Prodotto della ricerca)
• The CB(1) cannabinoid receptor antagonist AM251 attenuates amphetamine-induced behavioural sensitization while causing monoamine changes in nucleus accumbens and hippocampus (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis, cannabinoid receptor affinity, and molecular modeling studies of substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Novel sterically hindered cannabinoid CB1 receptor ligands. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• FAAH and anandamide: is 2-AG really the odd one out? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: Effect of high fat diets (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Short- and long-term plasticity of the endocannabinoid system in neuropsychiatric and neurological disorders (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF A POTENTINHIBITOR OF THE BIOSYNTHESIS OF THE ENDOCANNABINOID 2-ARACHIDONOYLGLYCEROL (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Gender-dependent cellular and biochemical effects of maternal deprivation on the hippocampus of neonatal rats: A possible role for the endocannabinoid system. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• INSULIN AS A NEGATIVE REGULATOR OF PLASMA ENDOCANNABINOID LEVELS IN OBESE AND NONOBESE SUBJECTS (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• ALTERATIONS OF BASAL AND FASTING/REFEEDING-REGULATED TISSUE LEVELS OF ENDOGENOUS N-ACYL-ETHANOLAMINE LIGANDS OF PPAR-± ™ Ÿ’ESE ZUCKER RATS (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Peripheral endocannabinoid dysregulation in obesity (Comunicazione a convegno) (Prodotto della ricerca)
• Endocannabinoids Are Endogenously Overproduced In Highly Malignant Ovarian Carcinoma: Possible Involvement Of Cox-2 In Their Tonic Control Of Cancer Spreading And Potential Pharmacological Relevancies (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophrenia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The biosynthesis, fate and pharmacological properties of endocannabinoids (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8. (Articolo in rivista) (Prodotto della ricerca)
• Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cell signalling: why fasting worms age slowly (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Occurrence and biological role of the endocannabinoid system in Ciona intestinalis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Anandamide-loaded nanoparticles: preparation and characterization. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid system and the molecular basis of paralytic ileus in mice (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidine. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Role for vanilloid receptor 1 (TRPV1) and endocannabinoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated rats (Articolo in rivista) (Prodotto della ricerca)
• Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors (Articolo in rivista) (Prodotto della ricerca)
• Neuropathic pain and the endocannabinoid system in the rat dorsal raphe: pharmacological treatment and interactions with the serotonergic system (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoids: synthesis and degradation (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoids in the brain and peripheral tissues: regulation of their levels and their implication in the control of food intake (Articolo in rivista) (Prodotto della ricerca)
• Cannabinoid CB1 receptor mediates fear extinction via habituation-like processes (Articolo in rivista) (Prodotto della ricerca)
• Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoid metabolic pathways and enzymes (Articolo in rivista) (Prodotto della ricerca)
• Increasing cannabinoid levels by pharmacological and genetic manipulation delays disease progression in SOD1 mice (Articolo in rivista) (Prodotto della ricerca)
• Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P (Articolo in rivista) (Prodotto della ricerca)
• A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson’s disease (Articolo in rivista) (Prodotto della ricerca)
• The endocannabinoid signaling system: biochemical aspects (Articolo in rivista) (Prodotto della ricerca)
• Finding of endocannabinoids in human eye tissues. Implications for glaucoma (Articolo in rivista) (Prodotto della ricerca)
• The Importance of Electrostatic Potential in The Interaction of Sweet Proteins with the Sweet Taste Receptor (Articolo in rivista) (Prodotto della ricerca)
• Anandamide as an intracellular messenger regulating ion channel activity (Articolo in rivista) (Prodotto della ricerca)
• Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis (Articolo in rivista) (Prodotto della ricerca)
• Involvement of the cannabimimetic compound, N-palmitoylethanolamine, in inflammatory and neuropathic conditions: A review of the available pre-clinical data, and first human studies (Articolo in rivista) (Prodotto della ricerca)
• CB2 receptors in mouse male germ cell differentiation (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• A novel approach to evaluate anandamide membrane transport into intact cells by using nanoparticle-mediated cellular uptake and controller release (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid signalling and the deteriorating brain (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Non-CB1, non-CB2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid and orexin-1 interactions in the hypothalamus: one possibile clue to obesity (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoid-based drugs with multiple sites of action: riding several horses against inflammation and hyper-reactivity (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Oxidative metabolism of lipoamino acids and vanilloids by lipoxygenases and cyclooxygenases (Articolo in rivista) (Prodotto della ricerca)
• Metabolically labile cannabinoid esters: A 'soft drug' approach for the development of cannabinoid-based therapeutic drugs (Articolo in rivista) (Prodotto della ricerca)
• The endovanilloid/endocannabinoid N-Arachidonoyl-Dopamine inhibits HIV-1 Replication in neuronal and non-neuronal cells. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoids control feeding in Carassius Auratus (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB1 receptors and endovanilloids (Articolo in rivista) (Prodotto della ricerca)
• The endocannabinoid system in principal forebrain neurons protects against excitotoxicity. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100ƒ² up-regulation in vitro (Articolo in rivista) (Prodotto della ricerca)
• Design, synthesis, binding and molecular modeling studies of new potent ligands of cannabinoid receptors (Articolo in rivista) (Prodotto della ricerca)
• Protective role of palmitoylethanolamide in keratinocytes and its involvement in contact allergic dermatitis. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Role of endocannabinoids in tumor progression: anandamide inhibits cell migration in human breast cancer cells. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Attenuation of allergic contact dermatitis through the endocannabinoid system (Articolo in rivista) (Prodotto della ricerca)
• Effect of plant cannabinoids on cancer cell proliferation. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• New structure activity relationship studies on CB1 receptor ligands (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Release of intracellular calcium by stimulation of PLC/IP3-pathway leads to anandamide formation in sensory neurons (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoids and the control of energy balance (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoids mediate retrograde signalling at excitatory and inhibitory synapses in the rat ventral tegmental area. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG. (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoids: synthesis and degradation (Articolo in rivista) (Prodotto della ricerca)
• Arvanil inhibits T-lynphocyte activation and ameliorates the course and progression of experimental autoimmune encephalomyelitis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• The chemotherapeutic agent cisplatin increases brain 2-arachidonoyl-glycerol (2-AG) concentrations and concomitantly reduces intestinal 2-AG and anandamide levels in a vomiting species (the least shrew). (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Latest advances in the discovery of fatty acid amide hydrolase inhibitors. (Articolo in rivista) (Prodotto della ricerca)
• Ihibitory effect of N-Arachidonoylserotonin, a FAAH inhibitor, on gastric and intestinal motility in mice. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• FAAH inhibition elevates endocannabinoid levels in the periaqueductal grey of the rat: dual effect on nociception via CB1 and TRPV1 receptors (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Effect of inhibitors of endocannabinoid uptake and FAAH on brain endocannabinoid levels. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Intracellular anandamide mediates store-operated calcium entry by acting at TRPV1 channels in neurons (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoids link feeding state and auditory perception-related gene expression. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Functional activity of cannabinoid receptors in models of adipocytes and ²-pancreatic cells. (Abstract/Poster in convegno) (Prodotto della ricerca)
• CB1, but not CB2, mediates stimulation of bone formation induced by traumatic brain injury. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Repeated treatment with selective inhibitors of the enzyme fatty-acid amide hydrolase alleviates neuropathic pain. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Differential control by GQ/G11 proteins of in vivo endocannabinoid levels and endocannabinoid-mediated regulation of neuronal excitability. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Neonatal stress-induced neurodegeneration: a suitable animal model to evaluate neuroprotective and modulatory properties of cannabinoids. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Enhancement of anandamide levels by thrombin and protein kinases C and A in sensory neurons. Implications for TRPV1 receptor activity. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Developement of a sensitive LC/MS-IT-TOF method for the identification and quantification of prostanoid derivatives of endocannabinoids. (Abstract/Poster in convegno) (Prodotto della ricerca)
• “Vanillipidomics”: an update on endogenous lipid ligands of vanilloid receptors. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Role of endocannabinoids and endovanilloids in Ca2+ signalling (Articolo in rivista) (Prodotto della ricerca)
• Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Solution Structure Of A Chemosensory Protein FromThe Desert Locust Schistocerca Gregaria (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• In vitro and in vivo pharmacology of synthetic olivetol-derived cannabinoid receptor ligands (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Divergent effects on skeletal muscle differentiation by cannabinoid receptor-1 (CB1) and voltage-gated potassium channel Kv7 stimulation in murine C2C12 cells (Abstract/Comunicazione in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1305)
• RETINAL PROJECTIONS TO THE LATERAL HYPOTHALAMUS ARE INVOLVED IN THE LIGHT-MEDIATED ENDOCANNABINOID SYNTHESIS: OREXIN AND 2-ACYLGLICEROL INTERACTION IN THE LIGHT-ENTRAINABLE RHYTHMS (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• LIVER AND ADIPOSE TISSUE ENDOCANNABINOID TONE IN DIET-INDUCEDOBESITY IS DEPENDENT ON APOLIPOPROTEIN E EXPRESSION ANDASSOCIATED WITH HEPATIC STEATOSIS AND INSULIN RESISTANCE (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• PROTECTIVE EFFECT OF CANNABIDIOL AND CANNABIS EXTRACT IN COLON CARCINOGENESIS (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Control of experimental spasticity by targeting the degradation of endocannabinoids using selective fatty acid amide hydrolase inhibitors. (Articolo in rivista) (Prodotto della ricerca)
• Cannabinomimetic lipid from a marine cyanobacterium (Articolo in rivista) (Prodotto della ricerca)
• Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2. (Articolo in rivista) (Prodotto della ricerca)
• ANANDAMIDE INJECTED INTRATHECALLY INDUCES ANALGESIA MEDIATED BY A TRPV1-DEPENDENT MECHANISM IN NEUROPATHIC RATS (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systems. (Articolo in rivista) (Prodotto della ricerca)
• Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. (Articolo in rivista) (Prodotto della ricerca)
• Semiplenamides A-G, fatty acid amides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena. (Articolo in rivista) (Prodotto della ricerca)
• Novel selective and metabolically stable inhibitors of anandamide cellular uptake. (Articolo in rivista) (Prodotto della ricerca)
• Prostaglandin ethanolamides (prostamides): in vitro pharmacology and metabolism. (Articolo in rivista) (Prodotto della ricerca)
• Endovanilloid degradation: comparative analysis of FAAH, COMT and TRPV1 expression in the mouse brain. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• The endocannabinoid system protects rat glioma cells against HIV-1 Tat protein-induced cytotoxicity - Mechanism and regulation (Articolo in rivista) (Prodotto della ricerca)
• Iodinated N-acylvanillamines. Potential \"multiple-target\" anti-inflammatory agents acting via inhibition of T cell activation and antagonism at vanilloid TRPV1 channels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Nonpsychotropic Plant Cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD), Activate and Desensitize Transient Receptor Potential Vanilloid 1 (TRPV1) Channels in Vitro: Potential for the Treatment of Neuronal Hyperexcitability (Articolo in rivista) (Prodotto della ricerca)
• Preparation and characterization of ?(9)-tetrahydrocannabinol-loaded biodegradable polymeric microparticles and their antitumoral efficacy on cancer cell lines. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Prostamide F2? receptor antagonists with inhibitory activity at FAAH: a way to prevent the confounding effects of pro-inflammatory mediators formed following selective FAAH inhibition? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoidomics: targeted lipidomics methods for the study of endocannabinoid-related molecules in the CNS (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Plant, synthetic and endogenous cannabinoids in medicine (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Lipids as regulators of the activity of transient receptor potential type V1 (TRPV1) channels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Targeted lipidomics profile and NMR metabolomics of injured mouse brain (Comunicazione a convegno) (Prodotto della ricerca)
• Why endocannabinoids are not all alike (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The 1,2,3-triazole ring as a peptido- and olefinomimetic element: discovery of click vanilloids and cannabinoids (Articolo in rivista) (Prodotto della ricerca)
• The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis (Articolo in rivista) (Prodotto della ricerca)
• Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structural Features of the Interaction Between Sdf-1 Analogues and the CXCR4 Receptor (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannnnabinoids and endocannabinoids in metabolic disorders with focus on diabetes. (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Development of a potent inhibitor of 2-arachidonoylglycerol hydrolysis with antinociceptive activity in vivo. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• LEPTIN-CONTROLLED OREXIN/ENDOCANNABINOID INTERACTIONS IN THE MOUSE PERIAQUEDUCTAL GREY: ROLE IN THE REGULATION OF THE DESCENDING ANTINOCICEPTIVE PATHWAY (Comunicazione a convegno) (Prodotto della ricerca)
• Prion Protein Misfolding: Conformational Stability of the a2-Helix (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• The functional plasticity of lipid mediators: the example of the endocannabinoids (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Non-CB1, non-CB2 receptors for endocannabinoids (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Endocannabinoid-based molecules as potential therapeutic drugs (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Lack of Effect of Fatty Acid Amide Hydrolase (FAAH) Inhibitors on Intraocular Pressure in Glaucomatous Monkeys (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Endocannabinoids as regulators of transient receptor potential (TRP) channels: A further opportunity to develop new endocannabinoid-based therapeutic drugs. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Exploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporter. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids and related compounds: walking back and forth between plant natural products and animal physiology (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Oxyhomologs of anandamide and related endolipids. Chemoselective synthesis and biological activity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects (Articolo in rivista) (Prodotto della ricerca)
• Homology modeling in tandem with 3D-QSAR analyses: a computational approach to depict the agonist binding site of the human CB2 receptor (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice (Articolo in rivista) (Prodotto della ricerca)
• Cannabinoids and schizophrenia: Therapeutic prospects (Articolo in rivista) (Prodotto della ricerca)
• Are cannabidiol and ?9 -tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review (Articolo in rivista) (Prodotto della ricerca)
• Temperature-Sensitive Transient Receptor Potential Channels as Ionotropic Cannabinoid Receptors (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• A new mutant of bovine seminal ribonuclease with a reversed swapping propensity. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The role of the CB1 cannabinoid receptor and its endogenous ligands, anandamide and 2-arachidonoylglycerol, in amphetamine-induced behavioural sensitization (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Role of osteopathic manipulative treatment in altering pain biomarkers: a pilot study (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Biochemistry and pharmacology of endovanilloids (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-fos expression in the hypothalamus (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Enantioselective synthesis of 1-(R)-hydroxypolygodial and its 9ƒÑ epimer, 1-(R)-hydroxyisotadeonal (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Periaqueductal grey metabotropic glutamate receptor 7 and 8 mediate opposite effects on amino acid release, RVM ON and OFF cell activities and nociception (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: potential use in companion animals (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Identification of endocannabinoids and related compounds in human fat cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids activate TRPV1 receptors to reduce hyperactivity related to hyperdopaminergia: therapeutic implications (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid overactivity and intestinal inflammation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Stereo- and enantio-specific activity of fatty acid cyclopropanolamides at cannabinoid and vanilloid receptors (Comunicazione a convegno) (Prodotto della ricerca)
• Endocannabinoid signaling and its regulation by nutrients (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Release of N-acylethanolamines by biomaterials of clinical relevance (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Analysis of Endocannabinoid System in a 3D \"cell-on-chip\" model of human tumors (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Novel selective and metabolically stable inhibitors of anandamide cellular uptake (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: an effective scaffold for the design of either CB1 or CB2 receptor ligands. (Articolo in rivista) (Prodotto della ricerca)
• Cannabinomimetic Lipid from a Marine Cyanobacterium. (Articolo in rivista) (Prodotto della ricerca)
• 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: An effective scaffold for the design of either CB(1) or CB(2) receptor ligands. (Articolo in rivista) (Prodotto della ricerca)
• Gut feelings about the endocannabinoid system. (Articolo in rivista) (Prodotto della ricerca)
• Protective role of cannabinoid receptor type 2 in a mouse model of diabetic nephropathy. (Articolo in rivista) (Prodotto della ricerca)
• Bioactive Prenylogous Cannabinoid from Fiber Hemp (Cannabis sativa). (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Alteration of the endocannabinoid system in mouse brain during prion disease. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoids generated by Ca2+ or by metabotropic glutamate receptors appear to arise from different pools of diacylglycerol lipase. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2. (Articolo in rivista) (Prodotto della ricerca)
• A gradient of 2-arachidonoylglycerol regulates mouse epididymal sperm cell start-up. (Articolo in rivista) (Prodotto della ricerca)
• An NMR spectroscopic method to identify and classify thiol-trapping agents: revival of Michael acceptors for drug discovery? (Articolo in rivista) (Prodotto della ricerca)
• An introduction to the endocannabinoid system: from the early to the latest concepts (Articolo in rivista) (Prodotto della ricerca)
• Functional lipidomics. Calcium-independent activation of endocannabinoid/endovanilloid lipid signalling in sensory neurons by protein kinases C and A and thrombin. (Articolo in rivista) (Prodotto della ricerca)
• Anti-inflammatory effect of palmitoylethanolamide on human adipocytes. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• New resorcinol-anandamide \"hybrids\" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Co-localization of TRPV1 and CB1 receptors in the mouse brain: an immunohistochemical study (Contributo in atti di convegno) (Prodotto della ricerca)
• Synthesis and pharmacological activity of a potent inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Regulation and possible role of endocannabinoids and related mediators in hypercholesterolemic mice with atherosclerosis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mechanisms for the coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma beta-cells. (Articolo in rivista) (Prodotto della ricerca)
• Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis (Articolo in rivista) (Prodotto della ricerca)
• The endocannabinoid system is modulated in response to spinal cord injury in rats. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid Research Group. Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Symptom-related changes of endocannabinoid and palmitoylethanolamide levels in brain areas of R6/2 mice, a transgenic model of Huntington's disease (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid system - Back to the scene of cardiometabolic risk factors control? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Care and feeding of the endocannabinoid system: A systematic review of potential clinical interventions that upregulate the endocannabinoid system (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids and neuropathic pain: Focus on neuron-glia and endocannabinoid-neurotrophin interactions (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Iron overload causes osteoporosis in Thalassemia Major patients through interaction with TRPV1 channels. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• (-)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels (Articolo in rivista) (Prodotto della ricerca)
• Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Nanoparticle-mediated cellular uptake-controlled release as a tool to study anandamide membrane transport (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endogenous cannabinoids: structure and metabolism (Articolo in rivista) (Prodotto della ricerca)
• Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret (Articolo in rivista) (Prodotto della ricerca)
• Structural Requirements for Proinflammatory Activity of Porin P2 Loop 7 from Haemophilus influenzae. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anti-cancer effects of cannabidiol in human breast carcinoma: cellular and molecular mechanisms of action and inhibition of metastatic spreading (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Rimonabant in rats with a metabolic syndrome: good news after the depression. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Development of the first potential covalent inhibitors of anandamide cellular uptake (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids, feeding and suckling - from our perspective (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid synthesis and degradation and their regulation in the framework of energy balance (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Regulation, function and dysregulation of endocannabinoids in models of adipose and b-pancreatic cells and in obesity and hyperglycemia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The levels of the endocannabinoid receptor CB2 and its ligand 2-Arachidonoylglycerol are elevated in endometrial carcinoma. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anandamide inhibits cell adhesion and migration of breast cancer cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A brief history of cannabinoid and endocannabinoid pharmacology as inspired by the work of British scientists (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Development of the first potent and specific inhibitors of endocannabinoid biosynthesis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Design, synthesis and binding studies of new potent ligands of cannabinoid receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid system in the brain of Carassius auratus and its possible role in the control of food intake (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cisplatin increases brain 2-arachidonoylglycerol (2-AG) and concomitantly reduces intestinal 2-AG and anandamide levels in the least shrew (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid receptors and their role in neuroprotection (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Fatty acid amide hydrolase controls mouse intestinal motility in vivo (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Development of the first ultra-potent “capsaicinoid” agonist at transient receptor potential type V1 (TRPV1) channels and its therapeutic potential (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The preferred conformation of the tripeptide Ala-Phe-Ala in water is an inverse g-turn: implications for protein folding and drug design (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation. (Articolo in rivista) (Prodotto della ricerca)
• Protective activation of the endocannabinoid system during ischemia in dopamine neurons. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Functional interaction between TRPV1 and micro-opioid receptors in the descending antinociceptive pathway activates glutamate transmission and induces analgesia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid system in obesity and type 2 diabetes (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis of multifunctionalized building blocks via vinylogous addition of Chan’s diene to carbonyl and carbonyl-related electrophiles, mediated by molecular iodine (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effect of the Cannabinoid Receptor-1 antagonist SR141716A on human adipocyte inflammatory profile and differentiation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 Receptor (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables: evidence for TRPA1-independent effects. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• N-arachidonoyldopamine tunes synaptic transmission onto dopaminergic neurones by activating both cannabinoid and vanilloid receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB(1) receptors: a keratinocyte-dependent effect. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Peripheral effects of the endocannabinoid system in energy homeostasis: adipose tissue, liver and skeletal muscle (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Desulfohaplosamate, a new phosphate-containing steroid from Dasychalina sp., is a selective cannabinoid CB2 receptor ligand (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid modulation in the olfactory epithelium. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidine. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Phytocannabinoids beyond the Cannabis plant - do they exist? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid 2-arachidonoyl-glycerol controls odor sensitivity in larvae of Xenopus laevis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anandamide enhances IL-10 production in activated microglia by targeting CB(2) receptors: roles of ERK1/2, JNK, and NF-kappaB. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB(2) receptor inverse agonists. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid receptor 1 blockade ameliorates albuminuria in experimental diabetic nephropathy. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Identificazione di relazioni tra i livelli di endocannabinoidi, endovanilloidi ed altre ammidi bioattive degli acidi grassi in tessuti, biopsie e sangue di animali da laboratorio e pazienti e alcune condizioni patologiche del sistema nervoso centrale e ga (Progetti) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1725)
• Dimostrazione che, nel caso di peptidi contenenti residui idrofili, solo il residuo glucopiranosile su Asn31 in hMOG(30–50) è in grado di riconoscere autoanticorpi nella sclerosi multipla. (Progetti) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1725)
• Endocannabinoid chemical biology: a tool for the development of novel therapies (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid system in metabolic control: a preface. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophrenia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structure-activity relationships of the ultrapotent vanilloid resiniferatoxin (RTX): The side chain benzylic methylene (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structure-activity relationships of the ultrapotent vanilloid resiniferatoxin (RTX): The homovanillyl moiety (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Tetrahydro-beta-carboline derivatives targeting fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channels. . (Articolo in rivista) (Prodotto della ricerca)
• Immunohistological localization of cannabinoid CB1 and vanilloid TRPV1 receptors in the mouse brain (Articolo in rivista) (Prodotto della ricerca)
• Synthesis, conformational analysis and CB(1) binding affinity of hairpin-like anandamide pseudopeptide mimetics (Articolo in rivista) (Prodotto della ricerca)
• Synthesis of a potential photoactivatable anandamide analog (Articolo in rivista) (Prodotto della ricerca)
• New metabolically stable fatty acid amide ligands of cannabinoid receptors: synthesis and receptor affinity studies (Articolo in rivista) (Prodotto della ricerca)
• New potent and selective inhibitors of anandamide re-uptake with anti-spastic activity in a mouse model of multiple sclerosis (Articolo in rivista) (Prodotto della ricerca)
• Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both CB1 and TRPV1 receptors (Articolo in rivista) (Prodotto della ricerca)
• First “hybrid” ligands of vanilloid TRPV1 and cannabinoid CB2 receptors and non-polyunsaturated fatty acid-derived CB2-selective ligands (Articolo in rivista) (Prodotto della ricerca)
• Structural features in EIAV NCp11: a lentivirus nucleocapsid protein with a short linker (Articolo in rivista) (Prodotto della ricerca)
• Activation of the endocannabinoid system as therapeutic approach in a murine model of multiple sclerosis (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoid control of food intake and energy balance (Articolo in rivista) (Prodotto della ricerca)
• Identification and Functional Characterization of Brainstem Cannabinoid CB2 Receptors (Articolo in rivista) (Prodotto della ricerca)
• Structural determinants of unexpected agonist activity in a retro-peptide analogue of the Sdf-1 a N-terminus (Articolo in rivista) (Prodotto della ricerca)
• The alpha to beta conformational transition of Alzheimer’s Ab-(1-42) peptide in aqueous media is reversible: a step by step conformational analysis pinpoints the location of the beta conformation seeding (Articolo in rivista) (Prodotto della ricerca)
• Zofenoprilat-glutathione mixed disulfide as a specific S-thiolating agent (Articolo in rivista) (Prodotto della ricerca)
• The Interaction of Highly Helical Structural Mutants with the NOP Receptor Discloses the Role of the Address Domain of Nociceptin/Orphanin FQ (Articolo in rivista) (Prodotto della ricerca)
• Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids: synthesis and degradation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• CB(1) receptor antagonism: biological basis for metabolic effects. (Articolo in rivista) (Prodotto della ricerca)
• New Potential Therapies from Vanilloid Transient Receptor Cation (TRPV) Channels. (Articolo in rivista) (Prodotto della ricerca)
• Effect of polyunsaturated fatty acids on endocannabinoid and N-acyl-ethanolamine levels in mouse adipocytes (Articolo in rivista) (Prodotto della ricerca)
• Regulation of hypothalamic endocannabinoid levels by neuropeptides and hormones involved in food intake and metabolism: insulin and melanocortins (Articolo in rivista) (Prodotto della ricerca)
• Targeting the endocannabinoid system: to enhance or reduce? (Articolo in rivista) (Prodotto della ricerca)
• Play an ADAGIO with a STRADIVARIUS: the right patient for CB1 receptor antagonists?” (Articolo in rivista) (Prodotto della ricerca)
• Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo (Articolo in rivista) (Prodotto della ricerca)
• Basal and fasting/refeeding-regulated tissue levels of endogenous PPAR-alpha ligands in Zucker rats (Articolo in rivista) (Prodotto della ricerca)
• Immunohistochemical localization of anabolic and catabolic enzymes for anandamide and other putative endovanilloids in the hippocampus and cerebellar cortex of the mouse brain (Articolo in rivista) (Prodotto della ricerca)
• Nuove molecole per la manipolazione farmacologica dei livelli di endocannabinoidi e ammidi bioattive di acidi grassi, con effetti terapeutici in modelli animali di sclerosi multipla, morbo di Parkinson ed Alzheimer e colite ulcerosa (Progetti) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1725)
• Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge eating disorder, but not in bulimia nervosa (Articolo in rivista) (Prodotto della ricerca)
• Scoperta della co-espressione dei recettori degli vanilloidi (TRPV1) e dei cannabinoidi (CB1) nel cervello di topo (Progetti) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1725)
• Enantioselective synthesis and vanilloid activity evaluation of 1-â-(p-methoxycinnamoyl)polygodial, an antinociceptive compound from Drymis winteri barks (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• New 1,8-naphthyridine and quinoline derivatives as CB(2) selective agonists (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structure-based virtual screening: identification of novel CB2 receptor ligands (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-induced atrophy in rats (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Opposing control of cannabinoid receptor stimulation on amyloid-{beta} induced reactive gliosis: in vitro and in vivo evidence (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Role and regulation of acylethanolamides in energy balance: focus on adipocytes and ƒÒ-cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids and the regulation of their levels in health and disease (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Depolarization-induced retrograde synaptic inhibition in the cerebellar cortex is mediated by 2-arachidonoylglycerol (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, associated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats. (Articolo in rivista) (Prodotto della ricerca)
• The prostamide analogue Bimatoprost inhibits adipogenic gene expression (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• INVOLVEMENT OF RETINAL PROJECTIONS TO THE LATERAL HYPOTHALAMUS IN LIGHT-MEDIATED ENDOCANNABINOID SYNTHESIS: CRITICAL ROLE OF OREXINERGIC AND ENDOCANNABINOID SYSTEMS IN LIGHT-ENTRAINABLE RHYTHMS (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Further evidence for the existence of a specific process for the membrane transport of anandamide. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• REGULATION AND POSSIBLE FUNCTION OF THE ENDOCANNABINOID SYSTEM IN MYOGENESIS (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• POTENTIAL OXIDATION OF 2-AG BY COX-2 ENHANCES MALONATE TOXICITY IN THE STRIATUM: RELEVANCE FOR CANNABINOID TREATMENTS IN HUNTINGTON’S DISEASE (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• POSSIBLE “ENTOURAGE” EFFECT OF PALMITOYLETHANOLAMIDE IN DOG AND HUMAN PLASMA (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Altered endocannabinoid signalling after a high-fat diet in Apoe (-/-) mice:relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance (Articolo in rivista) (Prodotto della ricerca)
• An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice. (Articolo in rivista) (Prodotto della ricerca)
• Possible endocannabinoid control of colorectal cancer growth. (Articolo in rivista) (Prodotto della ricerca)
• Selective inhibition of anandamide cellular uptake versus enzymatic hydrolysis--a difficult issue to handle. (Articolo in rivista) (Prodotto della ricerca)
• The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamine analogs with phenyl rings in the polar head group region (Articolo in rivista) (Prodotto della ricerca)
• A new strategy to block tumor growth by inhibiting endocannabinoid inactivation. (Articolo in rivista) (Prodotto della ricerca)
• Some like it pungent and vile. TRPA1 as a molecular target for the malodorous vinyl disulfides from asafoetida. (Articolo in rivista) (Prodotto della ricerca)
• Developement of new tetrazoles that selectively inhibit anandamide cellular uptake. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• On the “toxification” of anandamide by pathogenic fungi: formation of 3-hydroxy-anandamide and its activity on cannabinoid and TRPV1 receptors. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Tonic control of tumoral growth by endocannabinoids. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Mechanisms underlying in vivo neuroprotection by anandamide and the CB1/VR1 ‘hybrid’ agonist arvanil (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Tetrahydrolipstatin analogues: new selective pharmacological tools to investigate 2-AG metabolism (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Direct and indirect modulation of cannabinoid system in a phencyclidine model of schizophrenia (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• The role of 2-Arachidonylglycerol in retrograde signalling. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Protective activation of endogenous cannabinoids during ischemia in dopamine neurons (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Endogenous cannabinoids act at CB1 and CB2 receptors to inhibit emesis in the ferret (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Endocannabinoids levels in normal and glaucomatous human eye tissues (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• The endocannabinoid system is activated in response to spinal cord injury in rats. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Protective role of aliamides and endocannabinoid system during »-carrageenin-induced granuloma formation. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• In vitro and in vivo pharmacology of synthetic olivetol-derived cannabinoid receptor ligands. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Changes in endocannabinoid and palmitoylethanolamide levels in central and peripheral nervous systems in an animal model of neuropathic pain. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Overactivation of the endocannabinoid system in human endometrial carcinoma. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Alterations of endocannabinoid and acylethanolamide levels in peripheral tissues of mice on a high fat diet: implications for gastric emptying and metabolism. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Anandamide produced by Ca2+-insensitive enzymes induces excitation in primary sensory neurons (Articolo in rivista) (Prodotto della ricerca)
• Circulating endocannabinoids in insulin sensitive vs. Insulin resistant obese postmenopausal women. A MONET group study (Articolo in rivista) (Prodotto della ricerca)
• Mooreamide A: A cannabinomimetic lipid from the marine cyanobacterium Moorea bouillonii (Articolo in rivista) (Prodotto della ricerca)
• Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders (Articolo in rivista) (Prodotto della ricerca)
• The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Ligandi selettivi del recettore cannabinoide CB2 e loro possibili impieghi. (Brevetto) (Prodotto della ricerca)
• Method for treating pain – 1855Prov2 (Brevetto) (Prodotto della ricerca)
• Method for treating pain – 1831Prov1 (Brevetto) (Prodotto della ricerca)
• Method for treating pain – 1831Prov2 (Brevetto) (Prodotto della ricerca)
• Inhibitory effect of the anorexic compound oleoylethanolamide on gastric emptying in control and overweight mice (Articolo in rivista) (Prodotto della ricerca)
• Novel bioactive metabolites of dipyrone (metamizol). (Articolo in rivista) (Prodotto della ricerca)
• Levels of endocannabinoids and palmitoylethanolamide and their pharmacological manipulation in chronic granulomatous inflammation in rats. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Nuovi inibitori della degradazione degli endocannabinoidi con attività antagonistica sul recettore TRPV1, con effetti analgesici, antitumorali e anti-spastici (Progetti) (Prodotto della ricerca)
• Nuova metodologia di sintesi di derivati isossazolici attraverso reazioni di cicloaddizione 1,3-dipolare (1,3-DC) a partire da nitrocomposti primari, con utilizzo solo di una base in quantità catalitica (Progetti) (Prodotto della ricerca)
• PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines (Retraction of vol 714, pg 379, 2013) (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anandamide-loaded nanoparticles: preparation and characterization. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)

Codice

• PM.P01.012.001 (literal)

Anno di chiusura previsto

• 2017-01-01T00:00:00+01:00 (literal)

Istituto esecutore

• Institute of biomolecular chemistry (ICB) (Istituto)

Primo anno di attività

• 2005-01-01T00:00:00+01:00 (literal)

Abstract

• Malattie a lunga degenza e patologie inabilitanti hanno rilevanza sociale ed economica in paesi come l'Italia, dove l'età media della popolazione è in continuo aumento. Cercare nuovi e più efficienti farmaci per intervenire sul decorso di malattie che si protraggono nel tempo o anche solo sulla sintomatologia ed effetti inabilitanti significa puntare ad un decorso migliore per il paziente e ad una riduzione dei costi per terapie e strutture di sostegno. L'obiettivo di questo modulo è di creare i presupposti per la produzione di molecole per l'industria farmaceutica attraverso studi sulle interazioni molecolari tra proteine coinvolte in patologie e loro ligandi endogeni di natura lipidica, sfruttando, tra l'altro: 1) metodi di sintesi organica e \"molecular modelling\" per studi delle relazioni tra struttura e attività farmacologica di ligandi già noti; 2) approcci di lipidomica, per l'individuazione di nuovi mediatori lipidici coinvolti in patologie; 3) tecniche di biochimica, per lo screening in vitro delle attività farmacologiche di interesse; e 4) modelli animali delle patologie in esame per studi pre-clinici sui composti più interessanti, attraverso collaborazioni esterne. (literal)

Nome

• Struttura, funzione e \"profiling\" di endocannabinoidi e ammidi bioattive di acidi grassi implicati nelle patologie umane (literal)

Descrizione

• Descrizione collaborazioni del modulo "Struttura, funzione e \"profiling\" di endocannabinoidi e ammidi bioattive di acidi grassi implicati nelle patologie umane (PM.P01.012.001)" (Descrizione collaborazioni)
• Descrizione del modulo "Struttura, funzione e \"profiling\" di endocannabinoidi e ammidi bioattive di acidi grassi implicati nelle patologie umane (PM.P01.012.001)" (Descrizione modulo)
• Descrizione dello stato di avanzamento delle attività del modulo "Struttura, funzione e \"profiling\" di endocannabinoidi e ammidi bioattive di acidi grassi implicati nelle patologie umane (PM.P01.012.001)" (Descrizione stato avanzamento attività)

Modulo di

• Struttura e funzione di endocannabinoidi, endovanilloidi, ammidi bioattive di acidi grassi e lipo/glicopeptidi di interesse biomedico (PM.P01.012) (Commessa)

Gestore

• ALESSIA LIGRESTI (Persona)

Incoming links:

Gestore di

• ALESSIA LIGRESTI (Persona)

Modulo

• Struttura e funzione di endocannabinoidi, endovanilloidi, ammidi bioattive di acidi grassi e lipo/glicopeptidi di interesse biomedico (PM.P01.012) (Commessa)

Istituto esecutore di

• Institute of biomolecular chemistry (ICB) (Istituto)

Descrizione di

• Descrizione collaborazioni del modulo "Struttura, funzione e \"profiling\" di endocannabinoidi e ammidi bioattive di acidi grassi implicati nelle patologie umane (PM.P01.012.001)" (Descrizione collaborazioni)
• Descrizione del modulo "Struttura, funzione e \"profiling\" di endocannabinoidi e ammidi bioattive di acidi grassi implicati nelle patologie umane (PM.P01.012.001)" (Descrizione modulo)
• Descrizione dello stato di avanzamento delle attività del modulo "Struttura, funzione e \"profiling\" di endocannabinoidi e ammidi bioattive di acidi grassi implicati nelle patologie umane (PM.P01.012.001)" (Descrizione stato avanzamento attività)

Prodotto di

• The endocannabinoid system and the molecular basis of paralytic ileus in mice (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids: synthesis and degradation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The Interaction of Highly Helical Structural Mutants with the NOP Receptor Discloses the Role of the Address Domain of Nociceptin/Orphanin FQ (Articolo in rivista) (Prodotto della ricerca)
• Structural determinants of unexpected agonist activity in a retro-peptide analogue of the Sdf-1 a N-terminus (Articolo in rivista) (Prodotto della ricerca)
• The alpha to beta conformational transition of Alzheimer’s Ab-(1-42) peptide in aqueous media is reversible: a step by step conformational analysis pinpoints the location of the beta conformation seeding (Articolo in rivista) (Prodotto della ricerca)
• Zofenoprilat-glutathione mixed disulfide as a specific S-thiolating agent (Articolo in rivista) (Prodotto della ricerca)
• Structural features in EIAV NCp11: a lentivirus nucleocapsid protein with a short linker (Articolo in rivista) (Prodotto della ricerca)
• Activation of the endocannabinoid system as therapeutic approach in a murine model of multiple sclerosis (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoid control of food intake and energy balance (Articolo in rivista) (Prodotto della ricerca)
• Identification and Functional Characterization of Brainstem Cannabinoid CB2 Receptors (Articolo in rivista) (Prodotto della ricerca)
• New metabolically stable fatty acid amide ligands of cannabinoid receptors: synthesis and receptor affinity studies (Articolo in rivista) (Prodotto della ricerca)
• New potent and selective inhibitors of anandamide re-uptake with anti-spastic activity in a mouse model of multiple sclerosis (Articolo in rivista) (Prodotto della ricerca)
• Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both CB1 and TRPV1 receptors (Articolo in rivista) (Prodotto della ricerca)
• First “hybrid” ligands of vanilloid TRPV1 and cannabinoid CB2 receptors and non-polyunsaturated fatty acid-derived CB2-selective ligands (Articolo in rivista) (Prodotto della ricerca)
• Immunohistological localization of cannabinoid CB1 and vanilloid TRPV1 receptors in the mouse brain (Articolo in rivista) (Prodotto della ricerca)
• Synthesis, conformational analysis and CB(1) binding affinity of hairpin-like anandamide pseudopeptide mimetics (Articolo in rivista) (Prodotto della ricerca)
• Synthesis of a potential photoactivatable anandamide analog (Articolo in rivista) (Prodotto della ricerca)
• Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Depolarization-induced retrograde synaptic inhibition in the cerebellar cortex is mediated by 2-arachidonoylglycerol (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids and the regulation of their levels in health and disease (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structure-based virtual screening: identification of novel CB2 receptor ligands (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-induced atrophy in rats (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Opposing control of cannabinoid receptor stimulation on amyloid-{beta} induced reactive gliosis: in vitro and in vivo evidence (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Role and regulation of acylethanolamides in energy balance: focus on adipocytes and ƒÒ-cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Enantioselective synthesis and vanilloid activity evaluation of 1-â-(p-methoxycinnamoyl)polygodial, an antinociceptive compound from Drymis winteri barks (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• New 1,8-naphthyridine and quinoline derivatives as CB(2) selective agonists (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Play an ADAGIO with a STRADIVARIUS: the right patient for CB1 receptor antagonists?” (Articolo in rivista) (Prodotto della ricerca)
• Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo (Articolo in rivista) (Prodotto della ricerca)
• Targeting the endocannabinoid system: to enhance or reduce? (Articolo in rivista) (Prodotto della ricerca)
• New Potential Therapies from Vanilloid Transient Receptor Cation (TRPV) Channels. (Articolo in rivista) (Prodotto della ricerca)
• Effect of polyunsaturated fatty acids on endocannabinoid and N-acyl-ethanolamine levels in mouse adipocytes (Articolo in rivista) (Prodotto della ricerca)
• Regulation of hypothalamic endocannabinoid levels by neuropeptides and hormones involved in food intake and metabolism: insulin and melanocortins (Articolo in rivista) (Prodotto della ricerca)
• CB(1) receptor antagonism: biological basis for metabolic effects. (Articolo in rivista) (Prodotto della ricerca)
• Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophrenia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid chemical biology: a tool for the development of novel therapies (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid system in metabolic control: a preface. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anandamide enhances IL-10 production in activated microglia by targeting CB(2) receptors: roles of ERK1/2, JNK, and NF-kappaB. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB(2) receptor inverse agonists. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid receptor 1 blockade ameliorates albuminuria in experimental diabetic nephropathy. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidine. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Phytocannabinoids beyond the Cannabis plant - do they exist? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid 2-arachidonoyl-glycerol controls odor sensitivity in larvae of Xenopus laevis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid modulation in the olfactory epithelium. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB(1) receptors: a keratinocyte-dependent effect. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Peripheral effects of the endocannabinoid system in energy homeostasis: adipose tissue, liver and skeletal muscle (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Desulfohaplosamate, a new phosphate-containing steroid from Dasychalina sp., is a selective cannabinoid CB2 receptor ligand (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables: evidence for TRPA1-independent effects. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis of multifunctionalized building blocks via vinylogous addition of Chan’s diene to carbonyl and carbonyl-related electrophiles, mediated by molecular iodine (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effect of the Cannabinoid Receptor-1 antagonist SR141716A on human adipocyte inflammatory profile and differentiation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Resorcinol-sn-Glycerol Derivatives: Novel 2-Arachidonoylglycerol Mimetics Endowed with High Affinity and Selectivity for Cannabinoid Type 1 Receptor (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endogenous cannabinoids: structure and metabolism (Articolo in rivista) (Prodotto della ricerca)
• The endocannabinoid system in obesity and type 2 diabetes (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The preferred conformation of the tripeptide Ala-Phe-Ala in water is an inverse g-turn: implications for protein folding and drug design (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Development of the first ultra-potent “capsaicinoid” agonist at transient receptor potential type V1 (TRPV1) channels and its therapeutic potential (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cisplatin increases brain 2-arachidonoylglycerol (2-AG) and concomitantly reduces intestinal 2-AG and anandamide levels in the least shrew (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid receptors and their role in neuroprotection (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Fatty acid amide hydrolase controls mouse intestinal motility in vivo (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Design, synthesis and binding studies of new potent ligands of cannabinoid receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid system in the brain of Carassius auratus and its possible role in the control of food intake (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anandamide inhibits cell adhesion and migration of breast cancer cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A brief history of cannabinoid and endocannabinoid pharmacology as inspired by the work of British scientists (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Development of the first potent and specific inhibitors of endocannabinoid biosynthesis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Development of the first potential covalent inhibitors of anandamide cellular uptake (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids, feeding and suckling - from our perspective (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid synthesis and degradation and their regulation in the framework of energy balance (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Regulation, function and dysregulation of endocannabinoids in models of adipose and b-pancreatic cells and in obesity and hyperglycemia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Rimonabant in rats with a metabolic syndrome: good news after the depression. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids activate TRPV1 receptors to reduce hyperactivity related to hyperdopaminergia: therapeutic implications (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid overactivity and intestinal inflammation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Identification of endocannabinoids and related compounds in human fat cells (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: potential use in companion animals (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Biochemistry and pharmacology of endovanilloids (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-fos expression in the hypothalamus (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Enantioselective synthesis of 1-(R)-hydroxypolygodial and its 9ƒÑ epimer, 1-(R)-hydroxyisotadeonal (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Periaqueductal grey metabotropic glutamate receptor 7 and 8 mediate opposite effects on amino acid release, RVM ON and OFF cell activities and nociception (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Role of osteopathic manipulative treatment in altering pain biomarkers: a pilot study (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The role of the CB1 cannabinoid receptor and its endogenous ligands, anandamide and 2-arachidonoylglycerol, in amphetamine-induced behavioural sensitization (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid Research Group. Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Symptom-related changes of endocannabinoid and palmitoylethanolamide levels in brain areas of R6/2 mice, a transgenic model of Huntington's disease (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid system is modulated in response to spinal cord injury in rats. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• New resorcinol-anandamide \"hybrids\" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis and pharmacological activity of a potent inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Regulation and possible role of endocannabinoids and related mediators in hypercholesterolemic mice with atherosclerosis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anti-inflammatory effect of palmitoylethanolamide on human adipocytes. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2. (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Alteration of the endocannabinoid system in mouse brain during prion disease. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoids generated by Ca2+ or by metabotropic glutamate receptors appear to arise from different pools of diacylglycerol lipase. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Gut feelings about the endocannabinoid system. (Articolo in rivista) (Prodotto della ricerca)
• Protective role of cannabinoid receptor type 2 in a mouse model of diabetic nephropathy. (Articolo in rivista) (Prodotto della ricerca)
• Bioactive Prenylogous Cannabinoid from Fiber Hemp (Cannabis sativa). (Articolo in rivista) (Prodotto della ricerca)
• Cannabinomimetic Lipid from a Marine Cyanobacterium. (Articolo in rivista) (Prodotto della ricerca)
• 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: An effective scaffold for the design of either CB(1) or CB(2) receptor ligands. (Articolo in rivista) (Prodotto della ricerca)
• 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: an effective scaffold for the design of either CB1 or CB2 receptor ligands. (Articolo in rivista) (Prodotto della ricerca)
• The anandamide membrane transporter inhibitor, VDM-11, modulates sleep and c-Fos expression in the rat brain. (Articolo in rivista) (Prodotto della ricerca)
• Neuronal and glial alterations in the cerebellar cortex of maternally deprived rats: gender differences and modulatory effects of two inhibitors of endocannabinoid inactivation (Articolo in rivista) (Prodotto della ricerca)
• The Importance of Electrostatic Potential in The Interaction of Sweet Proteins with the Sweet Taste Receptor (Articolo in rivista) (Prodotto della ricerca)
• Anandamide as an intracellular messenger regulating ion channel activity (Articolo in rivista) (Prodotto della ricerca)
• Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis (Articolo in rivista) (Prodotto della ricerca)
• Involvement of the cannabimimetic compound, N-palmitoylethanolamine, in inflammatory and neuropathic conditions: A review of the available pre-clinical data, and first human studies (Articolo in rivista) (Prodotto della ricerca)
• A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson’s disease (Articolo in rivista) (Prodotto della ricerca)
• The endocannabinoid signaling system: biochemical aspects (Articolo in rivista) (Prodotto della ricerca)
• Finding of endocannabinoids in human eye tissues. Implications for glaucoma (Articolo in rivista) (Prodotto della ricerca)
• Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoid metabolic pathways and enzymes (Articolo in rivista) (Prodotto della ricerca)
• Increasing cannabinoid levels by pharmacological and genetic manipulation delays disease progression in SOD1 mice (Articolo in rivista) (Prodotto della ricerca)
• Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoids: synthesis and degradation (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoids in the brain and peripheral tissues: regulation of their levels and their implication in the control of food intake (Articolo in rivista) (Prodotto della ricerca)
• Cannabinoid CB1 receptor mediates fear extinction via habituation-like processes (Articolo in rivista) (Prodotto della ricerca)
• Role for vanilloid receptor 1 (TRPV1) and endocannabinoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated rats (Articolo in rivista) (Prodotto della ricerca)
• Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors (Articolo in rivista) (Prodotto della ricerca)
• Neuropathic pain and the endocannabinoid system in the rat dorsal raphe: pharmacological treatment and interactions with the serotonergic system (Articolo in rivista) (Prodotto della ricerca)
• In vitro and in vivo pharmacology of synthetic olivetol-derived cannabinoid receptor ligands (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Solution Structure Of A Chemosensory Protein FromThe Desert Locust Schistocerca Gregaria (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids and the control of energy balance (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoids: synthesis and degradation (Articolo in rivista) (Prodotto della ricerca)
• Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB1 receptors and endovanilloids (Articolo in rivista) (Prodotto della ricerca)
• Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100ƒ² up-regulation in vitro (Articolo in rivista) (Prodotto della ricerca)
• Design, synthesis, binding and molecular modeling studies of new potent ligands of cannabinoid receptors (Articolo in rivista) (Prodotto della ricerca)
• Attenuation of allergic contact dermatitis through the endocannabinoid system (Articolo in rivista) (Prodotto della ricerca)
• Oxidative metabolism of lipoamino acids and vanilloids by lipoxygenases and cyclooxygenases (Articolo in rivista) (Prodotto della ricerca)
• Metabolically labile cannabinoid esters: A 'soft drug' approach for the development of cannabinoid-based therapeutic drugs (Articolo in rivista) (Prodotto della ricerca)
• Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophrenia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Gender-dependent cellular and biochemical effects of maternal deprivation on the hippocampus of neonatal rats: A possible role for the endocannabinoid system. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Short- and long-term plasticity of the endocannabinoid system in neuropsychiatric and neurological disorders (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Novel sterically hindered cannabinoid CB1 receptor ligands. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• FAAH and anandamide: is 2-AG really the odd one out? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: Effect of high fat diets (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The CB(1) cannabinoid receptor antagonist AM251 attenuates amphetamine-induced behavioural sensitization while causing monoamine changes in nucleus accumbens and hippocampus (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis, cannabinoid receptor affinity, and molecular modeling studies of substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Brain TRPV1: a depressing TR(i)P down memory lane? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Rapid combinatorial access to a library of 1,5-disubstituted-3-indole-N-alkylacetamides as CB2 receptor ligands (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The biosynthesis of N-arachidonoyl dopamine (NADA), a putative endocannabinoid and endovanilloid, via conjugation of arachidonic acid with dopamine (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• From endocannabinoid profiling to 'endocannabinoid therapeutics' (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Rational design, synthesis, and pharmacological properties of new 1,8-naphthyridin-2(1H)-on-3-carboxamide derivatives as highly selective cannabinoid-2 receptor agonists (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Goldfish CB1 mRNA expression is affected by fasting and anandamide administration (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• CB1 antagonists for obesity--what lessons have we learned from rimonabant? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid CB1 receptor expression in relation to visceral adipose depots, endocannabinoid levels, microvascular damage, and the presence of the Cnr1 A3813G variant in humans (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis and biological evaluation of new potential inhibitors of N-acylethanolamine hydrolyzing acid amidase. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• N-palmitoyl-ethanolamine: Biochemistry and new therapeutic opportunities. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 20. Maternal dietary fat determines metabolic profile and the magnitude of endocannabinoid inhibition of the stress response in neonatal rat offspring. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Diacylglycerol lipase is not involved in depolarization-induced suppression of inhibition at unitary inhibitory connections in mouse hippocampus. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Possible Anandamide and Palmitoylethanolamide involvement in human stroke. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid receptors and endocannabinoids: role in neuroinflammatory and neurodegenerative disorders. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids: an appetite for fat. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Palmitoylethanolamide counteracts reactive astrogliosis induced by beta-amyloid peptide (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Use of palmitoylethanolamide in the entrapment neuropathy of the median in the wrist. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidine. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Impaired endocannabinoid levels in selected brain areas of transgenic R6/2 mice, and experimental model of Huntington’s disease. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Attenuation of allergic contact dermatitis through the endocannabinoid system. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways (Abstract/Poster in convegno) (Prodotto della ricerca)
• The endocannabinoid system in non-mammalian organisms: differences and commonalities with mammals (Abstract/Poster in convegno) (Prodotto della ricerca)
• Cannabinoid CB1 receptor activation inhibits MPTP-induced expression of S100B in glial cells thereby leading to survival of co-cultured neurons. Mechanism of action and involvement of endocannabinoids (Abstract/Poster in convegno) (Prodotto della ricerca)
• Novel selective inhibitors of anandamide re-uptake with anti-spastic activity in a mouse model of multiple sclerosis. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Peripheral up-regulation of the endocannabinoid system in obesity. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington’s disease. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Dual effect of inhibitors of endocannabinoid inactivation on memory retention in experimental models of Alzheimer’s disease (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Oxy-homologues of anandamide and related endolipids. Synthesis and biological evaluation. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Endocannabinoid and palmitoylethanolamide levels in eyes with diabetic retinopathy or macular degeneration (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Studies of the biosynthesis of N-Arachidonoyl Dopamine (NADA). (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Occurrence and biological role of the endocannabinoid system in Ciona Intestinalis (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Beneficial effects of inhibitors of the endocannabinoid transport in a rat model of Multiple Sclerosis: involvement of vanilloid TRPV1 receptors. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Evidence for a regulatory role of endocannabinoid system in the rat pineal gland activity. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Tissue distribution of 2-AG, PEA, ananadamide and Prostamides E2 and F2± in FAAH -/- and FAAH +/+ mice. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Synthesis and pharmacological evaluation of N-acylethanolamines oxygen homologated at the amide bond (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Enzymes for 2-AG biosynthesis and metabolism in cell lines, and their pharmacological inhibition. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• The taming of capsaicin. Synthesis and vanilloid antagonistic activity of isosteric and regioisomeric halononivamides and their products of halogen-carbon exchange (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Entourage effects of N-palmitoyldopamine and N-stearoyldopamine on N-arachidonoyldopamine activity. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Alterations in endocnnabinoid levels accompanying parkinsonism and levodopa-induced dyskinesia in the MPTP-lesioned macaque (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Effects of modulation of vanilloid and cannabinoid signalling on locomotion in normal animals and in animal models of Parkinson’s disease. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoids interfere with dendritic cells’life cycle by preventing the generation of mature DC (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• N-Oleoyldopamine: a novel endogenous lipid that activates VR1/CB1 receptors, produces hyperalgesia, and is recognized by the anandamide membrane transporter. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Homo-N-Arachidonoyl Dopamine mimics vanilloid receptor agonists in enhancing paired pulse depression of hippocampal population spikes. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Does acute lung inflammation lead to an increased synthesis of anandamide? A study in the mouse lung. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Dual effect of the cannabinoid agonist HU-210 on the vanilloid VR1 receptor-induced intracellular calcium in cells expressing both CB1 and VR1 receptors (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• The effects of chronic exposure, withdrawal and voluntary consumption of alcohol on the endocannabinoid transmission in reward-related brain regions: bases for a pharmacological management of this system to reduce alcohol preference. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoid signaling system in a rat model of Multiple Sclerosis: beneficial effects of the endocannabinoid uptake inhibition. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Sex-dependent degenerative changes in the cerebellar cortex of maternally deprived rats. Modulatory effects of two inhibitors of endocannabinoids inactivation. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Local administration of palmitoylethanolamide reduces chronic granuloma-associated pain in rats (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Effect of N-arachidonoylserotonin (AA-5-HT), a FAAH inhibitor with antagonistic activity at vanilloid TRPV1 receptor, in an animal model of acute inflammation. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Increased skin levels of the aliamide palmitoylethanolamide and endogenous fatty acid amides in dogs with atopic dermatitis. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• INSULIN AS A NEGATIVE REGULATOR OF PLASMA ENDOCANNABINOID LEVELS IN OBESE AND NONOBESE SUBJECTS (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• ALTERATIONS OF BASAL AND FASTING/REFEEDING-REGULATED TISSUE LEVELS OF ENDOGENOUS N-ACYL-ETHANOLAMINE LIGANDS OF PPAR-± ™ Ÿ’ESE ZUCKER RATS (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Peripheral endocannabinoid dysregulation in obesity (Comunicazione a convegno) (Prodotto della ricerca)
• Endocannabinoids Are Endogenously Overproduced In Highly Malignant Ovarian Carcinoma: Possible Involvement Of Cox-2 In Their Tonic Control Of Cancer Spreading And Potential Pharmacological Relevancies (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF A POTENTINHIBITOR OF THE BIOSYNTHESIS OF THE ENDOCANNABINOID 2-ARACHIDONOYLGLYCEROL (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• LIPID PROFILING OF HIGH-FAT-FED MICE AFTER DIETARY KRILL OIL SUPPLEMENTATION (Comunicazione a convegno) (Prodotto della ricerca)
• ACTIVATION OF SPINAL TRPV1 OR CB1 RECEPTORS IN NEUROPATHIC RATS DEPENDS ON ANANDAMIDE CONCENTRATION (Comunicazione a convegno) (Prodotto della ricerca)
• MECHANISMS OF THE ANTI-CANCER EFFECTS OF CANNABIDIOL AND OTHER NON-PSYCHOTROPIC CANNABINOIDS ON HUMAN PROSTATE CARCINOMA (Comunicazione a convegno) (Prodotto della ricerca)
• Why is prostate cancer a legitimate target for cannabinoids? (Comunicazione a convegno) (Prodotto della ricerca)
• Characterization of the endocannabinoid system during zebrafish (Danio rerio) embryogenesis and possible drug screening applications (Comunicazione a convegno) (Prodotto della ricerca)
• The prostamide analogue Bimatoprost inhibits adipogenic gene expression (Comunicazione a convegno) (Prodotto della ricerca)
• RETINOHYPOTHALAMIC PROJECTIONS TO LH ARE INVOLVED IN THE LIGHT-MEDIATED 2-AG ENDOCANNABINOID SYNTHESIS. CRITICAL ROLE OF OREXINERGIC AND ENDOCANNABINOID SYSTEMS IN LIGHT-ENTRAINABLE RHYTHMS (Comunicazione a convegno) (Prodotto della ricerca)
• Evaluation of oxidized linoleic acid metabolites as possible “endovanilloids” as compared to anandamide (Comunicazione a convegno) (Prodotto della ricerca)
• Overactivation of the endocannabinoid system in human endometrial carcinoma. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Alterations of endocannabinoid and acylethanolamide levels in peripheral tissues of mice on a high fat diet: implications for gastric emptying and metabolism. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• The endocannabinoid system is activated in response to spinal cord injury in rats. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Protective role of aliamides and endocannabinoid system during »-carrageenin-induced granuloma formation. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• In vitro and in vivo pharmacology of synthetic olivetol-derived cannabinoid receptor ligands. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Changes in endocannabinoid and palmitoylethanolamide levels in central and peripheral nervous systems in an animal model of neuropathic pain. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• The role of 2-Arachidonylglycerol in retrograde signalling. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Protective activation of endogenous cannabinoids during ischemia in dopamine neurons (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Endogenous cannabinoids act at CB1 and CB2 receptors to inhibit emesis in the ferret (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Endocannabinoids levels in normal and glaucomatous human eye tissues (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Tonic control of tumoral growth by endocannabinoids. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Mechanisms underlying in vivo neuroprotection by anandamide and the CB1/VR1 ‘hybrid’ agonist arvanil (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Tetrahydrolipstatin analogues: new selective pharmacological tools to investigate 2-AG metabolism (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Direct and indirect modulation of cannabinoid system in a phencyclidine model of schizophrenia (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Developement of new tetrazoles that selectively inhibit anandamide cellular uptake. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• On the “toxification” of anandamide by pathogenic fungi: formation of 3-hydroxy-anandamide and its activity on cannabinoid and TRPV1 receptors. (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• POSSIBLE “ENTOURAGE” EFFECT OF PALMITOYLETHANOLAMIDE IN DOG AND HUMAN PLASMA (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• REGULATION AND POSSIBLE FUNCTION OF THE ENDOCANNABINOID SYSTEM IN MYOGENESIS (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• POTENTIAL OXIDATION OF 2-AG BY COX-2 ENHANCES MALONATE TOXICITY IN THE STRIATUM: RELEVANCE FOR CANNABINOID TREATMENTS IN HUNTINGTON’S DISEASE (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• The prostamide analogue Bimatoprost inhibits adipogenic gene expression (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• INVOLVEMENT OF RETINAL PROJECTIONS TO THE LATERAL HYPOTHALAMUS IN LIGHT-MEDIATED ENDOCANNABINOID SYNTHESIS: CRITICAL ROLE OF OREXINERGIC AND ENDOCANNABINOID SYSTEMS IN LIGHT-ENTRAINABLE RHYTHMS (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Prion Protein Misfolding: Conformational Stability of the a2-Helix (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• The functional plasticity of lipid mediators: the example of the endocannabinoids (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Non-CB1, non-CB2 receptors for endocannabinoids (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Endocannabinoid-based molecules as potential therapeutic drugs (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Cannnnabinoids and endocannabinoids in metabolic disorders with focus on diabetes. (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Structural Features of the Interaction Between Sdf-1 Analogues and the CXCR4 Receptor (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• Neonatal stress-induced neurodegeneration: a suitable animal model to evaluate neuroprotective and modulatory properties of cannabinoids. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Enhancement of anandamide levels by thrombin and protein kinases C and A in sensory neurons. Implications for TRPV1 receptor activity. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Developement of a sensitive LC/MS-IT-TOF method for the identification and quantification of prostanoid derivatives of endocannabinoids. (Abstract/Poster in convegno) (Prodotto della ricerca)
• “Vanillipidomics”: an update on endogenous lipid ligands of vanilloid receptors. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Functional activity of cannabinoid receptors in models of adipocytes and ²-pancreatic cells. (Abstract/Poster in convegno) (Prodotto della ricerca)
• CB1, but not CB2, mediates stimulation of bone formation induced by traumatic brain injury. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Repeated treatment with selective inhibitors of the enzyme fatty-acid amide hydrolase alleviates neuropathic pain. (Abstract/Poster in convegno) (Prodotto della ricerca)
• Differential control by GQ/G11 proteins of in vivo endocannabinoid levels and endocannabinoid-mediated regulation of neuronal excitability. (Abstract/Poster in convegno) (Prodotto della ricerca)
• FAAH inhibition elevates endocannabinoid levels in the periaqueductal grey of the rat: dual effect on nociception via CB1 and TRPV1 receptors (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Effect of inhibitors of endocannabinoid uptake and FAAH on brain endocannabinoid levels. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Intracellular anandamide mediates store-operated calcium entry by acting at TRPV1 channels in neurons (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoids link feeding state and auditory perception-related gene expression. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoids mediate retrograde signalling at excitatory and inhibitory synapses in the rat ventral tegmental area. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Arvanil inhibits T-lynphocyte activation and ameliorates the course and progression of experimental autoimmune encephalomyelitis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• The chemotherapeutic agent cisplatin increases brain 2-arachidonoyl-glycerol (2-AG) concentrations and concomitantly reduces intestinal 2-AG and anandamide levels in a vomiting species (the least shrew). (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Ihibitory effect of N-Arachidonoylserotonin, a FAAH inhibitor, on gastric and intestinal motility in mice. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Role of endocannabinoids in tumor progression: anandamide inhibits cell migration in human breast cancer cells. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Effect of plant cannabinoids on cancer cell proliferation. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• New structure activity relationship studies on CB1 receptor ligands (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Release of intracellular calcium by stimulation of PLC/IP3-pathway leads to anandamide formation in sensory neurons (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• The endovanilloid/endocannabinoid N-Arachidonoyl-Dopamine inhibits HIV-1 Replication in neuronal and non-neuronal cells. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoids control feeding in Carassius Auratus (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• The endocannabinoid system in principal forebrain neurons protects against excitotoxicity. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Protective role of palmitoylethanolamide in keratinocytes and its involvement in contact allergic dermatitis. (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoid and orexin-1 interactions in the hypothalamus: one possibile clue to obesity (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoid-based drugs with multiple sites of action: riding several horses against inflammation and hyper-reactivity (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• ANANDAMIDE INJECTED INTRATHECALLY INDUCES ANALGESIA MEDIATED BY A TRPV1-DEPENDENT MECHANISM IN NEUROPATHIC RATS (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• LIVER AND ADIPOSE TISSUE ENDOCANNABINOID TONE IN DIET-INDUCEDOBESITY IS DEPENDENT ON APOLIPOPROTEIN E EXPRESSION ANDASSOCIATED WITH HEPATIC STEATOSIS AND INSULIN RESISTANCE (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• PROTECTIVE EFFECT OF CANNABIDIOL AND CANNABIS EXTRACT IN COLON CARCINOGENESIS (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• Divergent effects on skeletal muscle differentiation by cannabinoid receptor-1 (CB1) and voltage-gated potassium channel Kv7 stimulation in murine C2C12 cells (Abstract/Comunicazione in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1305)
• RETINAL PROJECTIONS TO THE LATERAL HYPOTHALAMUS ARE INVOLVED IN THE LIGHT-MEDIATED ENDOCANNABINOID SYNTHESIS: OREXIN AND 2-ACYLGLICEROL INTERACTION IN THE LIGHT-ENTRAINABLE RHYTHMS (Comunicazione a convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1303)
• The biosynthesis, fate and pharmacological properties of endocannabinoids (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Potential use of cannabimimetics in the treatment of cancer (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• Identificazione di relazioni tra i livelli di endocannabinoidi, endovanilloidi ed altre ammidi bioattive degli acidi grassi in tessuti, biopsie e sangue di animali da laboratorio e pazienti e alcune condizioni patologiche del sistema nervoso centrale e ga (Progetti) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1725)
• Dimostrazione che, nel caso di peptidi contenenti residui idrofili, solo il residuo glucopiranosile su Asn31 in hMOG(30–50) è in grado di riconoscere autoanticorpi nella sclerosi multipla. (Progetti) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1725)
• Nuove molecole per la manipolazione farmacologica dei livelli di endocannabinoidi e ammidi bioattive di acidi grassi, con effetti terapeutici in modelli animali di sclerosi multipla, morbo di Parkinson ed Alzheimer e colite ulcerosa (Progetti) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1725)
• Scoperta della co-espressione dei recettori degli vanilloidi (TRPV1) e dei cannabinoidi (CB1) nel cervello di topo (Progetti) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1725)
• Method for treating pain – 1831Prov2 (Brevetto) (Prodotto della ricerca)
• Method for treating pain – 1855Prov2 (Brevetto) (Prodotto della ricerca)
• Method for treating pain – 1831Prov1 (Brevetto) (Prodotto della ricerca)
• Ligandi selettivi del recettore cannabinoide CB2 e loro possibili impieghi. (Brevetto) (Prodotto della ricerca)
• Nuovi inibitori della degradazione degli endocannabinoidi con attività antagonistica sul recettore TRPV1, con effetti analgesici, antitumorali e anti-spastici (Progetti) (Prodotto della ricerca)
• Nuova metodologia di sintesi di derivati isossazolici attraverso reazioni di cicloaddizione 1,3-dipolare (1,3-DC) a partire da nitrocomposti primari, con utilizzo solo di una base in quantità catalitica (Progetti) (Prodotto della ricerca)
• Inhibitory effect of the anorexic compound oleoylethanolamide on gastric emptying in control and overweight mice (Articolo in rivista) (Prodotto della ricerca)
• Why endocannabinoids are not all alike (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Plant, synthetic and endogenous cannabinoids in medicine (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Iodinated N-acylvanillamines. Potential \"multiple-target\" anti-inflammatory agents acting via inhibition of T cell activation and antagonism at vanilloid TRPV1 channels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Homology modeling in tandem with 3D-QSAR analyses: a computational approach to depict the agonist binding site of the human CB2 receptor (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• N-arachidonoyldopamine tunes synaptic transmission onto dopaminergic neurones by activating both cannabinoid and vanilloid receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis (Articolo in rivista) (Prodotto della ricerca)
• Mechanisms for the coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma beta-cells. (Articolo in rivista) (Prodotto della ricerca)
• Functional lipidomics. Calcium-independent activation of endocannabinoid/endovanilloid lipid signalling in sensory neurons by protein kinases C and A and thrombin. (Articolo in rivista) (Prodotto della ricerca)
• The levels of the endocannabinoid receptor CB2 and its ligand 2-Arachidonoylglycerol are elevated in endometrial carcinoma. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anti-cancer effects of cannabidiol in human breast carcinoma: cellular and molecular mechanisms of action and inhibition of metastatic spreading (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Structural Requirements for Proinflammatory Activity of Porin P2 Loop 7 from Haemophilus influenzae. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: a critical revisitation (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cannabinoid CB1 receptor elevation of intracellular calcium in neuroblastoma SH-SY5Y cells: interactions with muscarinic and delta-opioid receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Cell signalling: why fasting worms age slowly (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anandamide-loaded nanoparticles: preparation and characterization. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens (Articolo in rivista) (Prodotto della ricerca)
• The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption (Articolo in rivista) (Prodotto della ricerca)
• Role of endocannabinoids and endovanilloids in Ca2+ signalling (Articolo in rivista) (Prodotto della ricerca)
• Endovanilloid degradation: comparative analysis of FAAH, COMT and TRPV1 expression in the mouse brain. (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, associated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats. (Articolo in rivista) (Prodotto della ricerca)
• Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Further evidence for the existence of a specific process for the membrane transport of anandamide. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• 2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents. (Articolo in rivista) (Prodotto della ricerca)
• Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge eating disorder, but not in bulimia nervosa (Articolo in rivista) (Prodotto della ricerca)
• Immunohistochemical localization of anabolic and catabolic enzymes for anandamide and other putative endovanilloids in the hippocampus and cerebellar cortex of the mouse brain (Articolo in rivista) (Prodotto della ricerca)
• Basal and fasting/refeeding-regulated tissue levels of endogenous PPAR-alpha ligands in Zucker rats (Articolo in rivista) (Prodotto della ricerca)
• Levels of endocannabinoids and palmitoylethanolamide and their pharmacological manipulation in chronic granulomatous inflammation in rats. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids: some like it fat (and sweet too). (Articolo in rivista) (Prodotto della ricerca)
• New N-arachidonoylserotonin analogues with potential 'dual' mechanism of action against pain. (Articolo in rivista) (Prodotto della ricerca)
• Altered endocannabinoid signalling after a high-fat diet in Apoe (-/-) mice:relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance (Articolo in rivista) (Prodotto della ricerca)
• The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A new mutant of bovine seminal ribonuclease with a reversed swapping propensity. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Lack of Effect of Fatty Acid Amide Hydrolase (FAAH) Inhibitors on Intraocular Pressure in Glaucomatous Monkeys (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• LEPTIN-CONTROLLED OREXIN/ENDOCANNABINOID INTERACTIONS IN THE MOUSE PERIAQUEDUCTAL GREY: ROLE IN THE REGULATION OF THE DESCENDING ANTINOCICEPTIVE PATHWAY (Comunicazione a convegno) (Prodotto della ricerca)
• The 1,2,3-triazole ring as a peptido- and olefinomimetic element: discovery of click vanilloids and cannabinoids (Articolo in rivista) (Prodotto della ricerca)
• Nanoparticle-mediated cellular uptake-controlled release as a tool to study anandamide membrane transport (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• (-)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels (Articolo in rivista) (Prodotto della ricerca)
• Co-localization of TRPV1 and CB1 receptors in the mouse brain: an immunohistochemical study (Contributo in atti di convegno) (Prodotto della ricerca)
• Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret (Articolo in rivista) (Prodotto della ricerca)
• Novel selective and metabolically stable inhibitors of anandamide cellular uptake (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Stereo- and enantio-specific activity of fatty acid cyclopropanolamides at cannabinoid and vanilloid receptors (Comunicazione a convegno) (Prodotto della ricerca)
• The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis (Articolo in rivista) (Prodotto della ricerca)
• Novel bioactive metabolites of dipyrone (metamizol). (Articolo in rivista) (Prodotto della ricerca)
• Development of a potent inhibitor of 2-arachidonoylglycerol hydrolysis with antinociceptive activity in vivo. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Lipids as regulators of the activity of transient receptor potential type V1 (TRPV1) channels (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Oxyhomologs of anandamide and related endolipids. Chemoselective synthesis and biological activity (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids and related compounds: walking back and forth between plant natural products and animal physiology (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids as regulators of transient receptor potential (TRP) channels: A further opportunity to develop new endocannabinoid-based therapeutic drugs. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Exploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporter. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Functional interaction between TRPV1 and micro-opioid receptors in the descending antinociceptive pathway activates glutamate transmission and induces analgesia (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Protective activation of the endocannabinoid system during ischemia in dopamine neurons. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structure-activity relationships of the ultrapotent vanilloid resiniferatoxin (RTX): The homovanillyl moiety (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Structure-activity relationships of the ultrapotent vanilloid resiniferatoxin (RTX): The side chain benzylic methylene (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma (Articolo in rivista) (Prodotto della ricerca)
• An introduction to the endocannabinoid system: from the early to the latest concepts (Articolo in rivista) (Prodotto della ricerca)
• A gradient of 2-arachidonoylglycerol regulates mouse epididymal sperm cell start-up. (Articolo in rivista) (Prodotto della ricerca)
• An NMR spectroscopic method to identify and classify thiol-trapping agents: revival of Michael acceptors for drug discovery? (Articolo in rivista) (Prodotto della ricerca)
• Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation. (Articolo in rivista) (Prodotto della ricerca)
• The taming of capsaicin. Reversal of the vanilloid activity of N-acylvanillamines by aromatic iodination (Articolo in rivista) (Prodotto della ricerca)
• TRPV1 receptors in the central nervous system: potential for previously unforeseen therapeutic applications (Articolo in rivista) (Prodotto della ricerca)
• The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation (Articolo in rivista) (Prodotto della ricerca)
• TRPV1 channels control synaptic plasticity in the developing superior colliculus (Articolo in rivista) (Prodotto della ricerca)
• Synergistic effects of CB1, muscarinic and ´-opioid receptor agonists on intracellular Ca2+ mobilization in SH-SY5Y cells (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Endocannabinoidomics: targeted lipidomics methods for the study of endocannabinoid-related molecules in the CNS (Abstract/Poster in atti di convegno) (Prodotto della ricerca)
• A novel approach to evaluate anandamide membrane transport into intact cells by using nanoparticle-mediated cellular uptake and controller release (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• CB2 receptors in mouse male germ cell differentiation (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Non-CB1, non-CB2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endovanilloid/endocannabinoid system: a new potential target for osteoporosis therapy. (Articolo in rivista) (Prodotto della ricerca)
• Protective role of palmitoylethanolamide in contact allergic dermatitis (Articolo in rivista) (Prodotto della ricerca)
• Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8. (Articolo in rivista) (Prodotto della ricerca)
• A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects (Articolo in rivista) (Prodotto della ricerca)
• Tetrahydro-beta-carboline derivatives targeting fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channels. . (Articolo in rivista) (Prodotto della ricerca)
• Occurrence and biological role of the endocannabinoid system in Ciona intestinalis (Abstract/Poster in atti di convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1302)
• Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. (Articolo in rivista) (Prodotto della ricerca)
• Temperature-Sensitive Transient Receptor Potential Channels as Ionotropic Cannabinoid Receptors (Contributo in volume (capitolo o saggio)) (Prodotto della ricerca)
• The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG. (Articolo in rivista) (Prodotto della ricerca)
• Latest advances in the discovery of fatty acid amide hydrolase inhibitors. (Articolo in rivista) (Prodotto della ricerca)
• Effect of chirality and lipophilicity in the functional activity of evodiamine and its analogues at TRPV1 channels. (Articolo in rivista) (Prodotto della ricerca)
• Some like it pungent and vile. TRPA1 as a molecular target for the malodorous vinyl disulfides from asafoetida. (Articolo in rivista) (Prodotto della ricerca)
• Control of experimental spasticity by targeting the degradation of endocannabinoids using selective fatty acid amide hydrolase inhibitors. (Articolo in rivista) (Prodotto della ricerca)
• Preparation and characterization of ?(9)-tetrahydrocannabinol-loaded biodegradable polymeric microparticles and their antitumoral efficacy on cancer cell lines. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Prostamide F2? receptor antagonists with inhibitory activity at FAAH: a way to prevent the confounding effects of pro-inflammatory mediators formed following selective FAAH inhibition? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Are cannabidiol and ?9 -tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review (Articolo in rivista) (Prodotto della ricerca)
• Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice (Articolo in rivista) (Prodotto della ricerca)
• Cannabinoids and schizophrenia: Therapeutic prospects (Articolo in rivista) (Prodotto della ricerca)
• Nonpsychotropic Plant Cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD), Activate and Desensitize Transient Receptor Potential Vanilloid 1 (TRPV1) Channels in Vitro: Potential for the Treatment of Neuronal Hyperexcitability (Articolo in rivista) (Prodotto della ricerca)
• The endocannabinoid system protects rat glioma cells against HIV-1 Tat protein-induced cytotoxicity - Mechanism and regulation (Articolo in rivista) (Prodotto della ricerca)
• Prostaglandin ethanolamides (prostamides): in vitro pharmacology and metabolism. (Articolo in rivista) (Prodotto della ricerca)
• Semiplenamides A-G, fatty acid amides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena. (Articolo in rivista) (Prodotto della ricerca)
• Novel selective and metabolically stable inhibitors of anandamide cellular uptake. (Articolo in rivista) (Prodotto della ricerca)
• Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systems. (Articolo in rivista) (Prodotto della ricerca)
• Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2. (Articolo in rivista) (Prodotto della ricerca)
• Cannabinomimetic lipid from a marine cyanobacterium (Articolo in rivista) (Prodotto della ricerca)
• Targeted lipidomics profile and NMR metabolomics of injured mouse brain (Comunicazione a convegno) (Prodotto della ricerca)
• Mooreamide A: A cannabinomimetic lipid from the marine cyanobacterium Moorea bouillonii (Articolo in rivista) (Prodotto della ricerca)
• Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders (Articolo in rivista) (Prodotto della ricerca)
• Anandamide produced by Ca2+-insensitive enzymes induces excitation in primary sensory neurons (Articolo in rivista) (Prodotto della ricerca)
• Circulating endocannabinoids in insulin sensitive vs. Insulin resistant obese postmenopausal women. A MONET group study (Articolo in rivista) (Prodotto della ricerca)
• The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamine analogs with phenyl rings in the polar head group region (Articolo in rivista) (Prodotto della ricerca)
• A new strategy to block tumor growth by inhibiting endocannabinoid inactivation. (Articolo in rivista) (Prodotto della ricerca)
• Selective inhibition of anandamide cellular uptake versus enzymatic hydrolysis--a difficult issue to handle. (Articolo in rivista) (Prodotto della ricerca)
• An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice. (Articolo in rivista) (Prodotto della ricerca)
• Possible endocannabinoid control of colorectal cancer growth. (Articolo in rivista) (Prodotto della ricerca)
• Anandamide receptors (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• New analgesics synthetically derived from the paracetamol metabolite N-(4-hydroxyphenyl)-(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-enamide (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Anandamide-loaded nanoparticles: preparation and characterization. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines (Retraction of vol 714, pg 379, 2013) (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoid signaling and its regulation by nutrients (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Release of N-acylethanolamines by biomaterials of clinical relevance (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Analysis of Endocannabinoid System in a 3D \"cell-on-chip\" model of human tumors (Abstract/Poster in convegno) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1304)
• Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Iron overload causes osteoporosis in Thalassemia Major patients through interaction with TRPV1 channels. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid system - Back to the scene of cardiometabolic risk factors control? (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Care and feeding of the endocannabinoid system: A systematic review of potential clinical interventions that upregulate the endocannabinoid system (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Endocannabinoids and neuropathic pain: Focus on neuron-glia and endocannabinoid-neurotrophin interactions (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Acute resistance exercise induces antinociception by activation of the endocannabinoid system in rats (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Effect of narrowband ultraviolet B treatment on endocannabinoid plasma levels in patients with psoriasis (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Glutamate spillover drives endocannabinoid production and inhibits GABAergic transmission in the Substantia Nigra pars compacta (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• The endocannabinoid system mediates aerobic exercise-induced antinociception in rats (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake. (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• A structure-activity relationship study on N-arachidonoyl-amino acids as possible endogenous inhibitors of fatty acid amide hydrolase. (Articolo in rivista) (Prodotto della ricerca)
• Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. (Articolo in rivista) (Prodotto della ricerca)
• Homologues and isomers of noladin ether, a putative novel endocannabinoid: interaction with rat cannabinoid CB(1) receptors. (Articolo in rivista) (Prodotto della ricerca)
• The First Dual ChE/FAAH Inhibitors: New Perspectives for Alzheimer's Disease? (Articolo in rivista) (Prodotto della ricerca)
• CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides. (Articolo in rivista) (Prodotto della ricerca)
• Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase ? and ?/?-hydrolase domain 6 (Articolo in rivista) (Prodotto della ricerca)
• 1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor. (Articolo in rivista) (Prodotto della ricerca)
• Endocannabinoid signalling and the deteriorating brain (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands (Articolo in rivista) (http://www.cnr.it/ontology/cnr/individuo/prodotto/TIPO1101)
• http://www.cnr.it/ontology/cnr/individuo/prodotto/ID289464
• http://www.cnr.it/ontology/cnr/individuo/prodotto/ID297107